SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

B5ZV40

- SYL_RHILW

UniProt

B5ZV40 - SYL_RHILW

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Leucine--tRNA ligase
Gene
leuS, Rleg2_3924
Organism
Rhizobium leguminosarum bv. trifolii (strain WSM2304)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei635 – 6351ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. aminoacyl-tRNA editing activity Source: InterPro
  3. leucine-tRNA ligase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. leucyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciRLEG395492:GJB3-3980-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Leucine--tRNA ligase (EC:6.1.1.4)
Alternative name(s):
Leucyl-tRNA synthetase
Short name:
LeuRS
Gene namesi
Name:leuS
Ordered Locus Names:Rleg2_3924
OrganismiRhizobium leguminosarum bv. trifolii (strain WSM2304)
Taxonomic identifieri395492 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium
ProteomesiUP000008330: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 876876Leucine--tRNA ligaseUniRule annotation
PRO_1000091351Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi395492.Rleg2_3924.

Structurei

3D structure databases

ProteinModelPortaliB5ZV40.

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi43 – 5311"HIGH" regionUniRule annotation
Add
BLAST
Motifi632 – 6365"KMSKS" regionUniRule annotation

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0495.
HOGENOMiHOG000200747.
KOiK01869.
OMAiHISHELW.
OrthoDBiEOG63Z74X.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.40.50.620. 3 hits.
3.90.740.10. 1 hit.
HAMAPiMF_00049_B. Leu_tRNA_synth_B.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR002300. aa-tRNA-synth_Ia.
IPR002302. Leu-tRNA-ligase.
IPR025709. Leu_tRNA-synth_edit.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view]
PANTHERiPTHR11946:SF7. PTHR11946:SF7. 1 hit.
PfamiPF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 3 hits.
PF13603. tRNA-synt_1_2. 1 hit.
[Graphical view]
PRINTSiPR00985. TRNASYNTHLEU.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
TIGRFAMsiTIGR00396. leuS_bact. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B5ZV40-1 [UniParc]FASTAAdd to Basket

« Hide

MATERYNPRD AEPRWQQKWN EDKVFETDNS DPREKYYVLE MFPYPSGRIH    50
MGHVRNYAMG DVVARYKRAR GYNVLHPMGW DAFGMPAENA AMERGVHPAS 100
WTYQNIGSMK AQLKAMGLSL DWSREFATCD VEYYQHQQHL FLDFLEKGLV 150
YRKQSKVNWD PVDNTVLANE QVIDGRGWRS GALVEQRELT QWFFKITDFS 200
QDLLDALDTL DQWPEKVRLM QKNWIGRSEG LTIRWEIVAE TAPAGETEIT 250
VYTTRPDTLF GASFLAIAAD HPLAKDAAAK NADIEAFCEE CRRAGTSLAA 300
LETAEKKGMD TGIRVRHPLD PSWELPVYVA NFVLMDYGTG AIFGCPSGDQ 350
RDLDFARKYG LPVVAVVMPQ DGDAASFSVG DTAYDGDGVM INSRFLDGKT 400
TEEAFNIVAD RLSAASLGNT PQGERKVNFR LRDWGISRQR YWGCPIPVIH 450
CDDCGVVPVP KKDLPVKLPD DVTFDQPGNP LDRHPTWRHV SCPTCGKDAR 500
RETDTMDTFV DSSWYFTRFT APWEAKPTDP EAANRWLPVD QYIGGIEHAI 550
LHLLYSRFFT RAMRETGHVA ATEPFKGLFT QGMVVHETYS RGAGGSREWV 600
APADIRIEEI DGKRRALLLT TGEEIAIGSI EKMSKSKKNV VDPDDIIASY 650
GADTARFFVL SDSPPERDVI WSEAGVEGAH RFTQRLWRLI SEAADALSAV 700
APAPATEGEA LSISQAAHRT LKAVENDYDK LWFNKAVARI YELVNALAAP 750
MTRVAAGEGD ATYRAAVRNA AEILIQLVAP MTPHLAEECW MALGNEGLLA 800
RTGWPQYGET LVIENDVVLP VQINGKKRAE LTISRDADQN AVTNAVLDLD 850
AVKNALNGQA PKKIIVVPQR IVNIVV 876
Length:876
Mass (Da):97,894
Last modified:November 25, 2008 - v1
Checksum:i936E5BB1414FE104
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001191 Genomic DNA. Translation: ACI57186.1.
RefSeqiYP_002283412.1. NC_011369.1.

Genome annotation databases

EnsemblBacteriaiACI57186; ACI57186; Rleg2_3924.
GeneIDi6982688.
KEGGirlt:Rleg2_3924.
PATRICi23132136. VBIRhiLeg95088_5867.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001191 Genomic DNA. Translation: ACI57186.1 .
RefSeqi YP_002283412.1. NC_011369.1.

3D structure databases

ProteinModelPortali B5ZV40.
ModBasei Search...

Protein-protein interaction databases

STRINGi 395492.Rleg2_3924.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACI57186 ; ACI57186 ; Rleg2_3924 .
GeneIDi 6982688.
KEGGi rlt:Rleg2_3924.
PATRICi 23132136. VBIRhiLeg95088_5867.

Phylogenomic databases

eggNOGi COG0495.
HOGENOMi HOG000200747.
KOi K01869.
OMAi HISHELW.
OrthoDBi EOG63Z74X.

Enzyme and pathway databases

BioCyci RLEG395492:GJB3-3980-MONOMER.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.40.50.620. 3 hits.
3.90.740.10. 1 hit.
HAMAPi MF_00049_B. Leu_tRNA_synth_B.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR002300. aa-tRNA-synth_Ia.
IPR002302. Leu-tRNA-ligase.
IPR025709. Leu_tRNA-synth_edit.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view ]
PANTHERi PTHR11946:SF7. PTHR11946:SF7. 1 hit.
Pfami PF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 3 hits.
PF13603. tRNA-synt_1_2. 1 hit.
[Graphical view ]
PRINTSi PR00985. TRNASYNTHLEU.
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
TIGRFAMsi TIGR00396. leuS_bact. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome of Rhizobium leguminosarum bv. trifolii WSM2304."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Yates R.
    , Ardley J., Tiwari R.P., O'Hara G., Howieson J., Brau L., Reeve W.
    Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: WSM2304.

Entry informationi

Entry nameiSYL_RHILW
AccessioniPrimary (citable) accession number: B5ZV40
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: November 25, 2008
Last modified: May 14, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi