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Protein

Glutaminase

Gene

glsA

Organism
Rhizobium leguminosarum bv. trifolii (strain WSM2304)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei64SubstrateUniRule annotation1
Binding sitei114SubstrateUniRule annotation1
Binding sitei160SubstrateUniRule annotation1
Binding sitei167SubstrateUniRule annotation1
Binding sitei191SubstrateUniRule annotation1
Binding sitei243SubstrateUniRule annotation1
Binding sitei261Substrate; via amide nitrogenUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
Gene namesi
Name:glsAUniRule annotation
Ordered Locus Names:Rleg2_1946
OrganismiRhizobium leguminosarum bv. trifolii (strain WSM2304)
Taxonomic identifieri395492 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium
Proteomesi
  • UP000008330 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001157021 – 309GlutaminaseAdd BLAST309

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi395492.Rleg2_1946.

Structurei

3D structure databases

ProteinModelPortaliB5ZRF0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CSV. Bacteria.
COG2066. LUCA.
HOGENOMiHOG000216890.
KOiK01425.
OMAiANYMKSF.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase. 1 hit.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

B5ZRF0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADLQAILDS IHTDILPRIG EGKVADYIPE LAKVDPRQFG MAIVTVDGKV
60 70 80 90 100
YRVGDADIAF SIQSISKVFM LTLALGKVGE SLWKRVGREP SGSAFNSIVQ
110 120 130 140 150
LEHEGGIPRN PFINAGAIAV SDVVMAGHAP REAIGELLRF VRYLADDESI
160 170 180 190 200
TIDDKVARSE TQTGYRNVAL ANFMRAYRNL DHPVDHVLGV YFHQCALSMS
210 220 230 240 250
CEQLARAGLF LAARGSNPMT GHSVVSPKRA RRINALMLTC GHYDGSGDFA
260 270 280 290 300
YHVGLPGKSG VGGGIFAVAP GIASIAVWSP GLNKVGNSQL GAVALEMLAA

RTGWSVFGD
Length:309
Mass (Da):32,977
Last modified:November 25, 2008 - v1
Checksum:i43F3D00A335F9516
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001191 Genomic DNA. Translation: ACI55231.1.
RefSeqiWP_003586217.1. NC_011369.1.

Genome annotation databases

EnsemblBacteriaiACI55231; ACI55231; Rleg2_1946.
KEGGirlt:Rleg2_1946.
PATRICi23127942. VBIRhiLeg95088_3793.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001191 Genomic DNA. Translation: ACI55231.1.
RefSeqiWP_003586217.1. NC_011369.1.

3D structure databases

ProteinModelPortaliB5ZRF0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi395492.Rleg2_1946.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACI55231; ACI55231; Rleg2_1946.
KEGGirlt:Rleg2_1946.
PATRICi23127942. VBIRhiLeg95088_3793.

Phylogenomic databases

eggNOGiENOG4105CSV. Bacteria.
COG2066. LUCA.
HOGENOMiHOG000216890.
KOiK01425.
OMAiANYMKSF.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase. 1 hit.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiGLSA_RHILW
AccessioniPrimary (citable) accession number: B5ZRF0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: November 25, 2008
Last modified: November 2, 2016
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.