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B5ZRF0

- GLSA_RHILW

UniProt

B5ZRF0 - GLSA_RHILW

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Protein
Glutaminase
Gene
glsA, Rleg2_1946
Organism
Rhizobium leguminosarum bv. trifolii (strain WSM2304)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei64 – 641Substrate By similarity
Binding sitei114 – 1141Substrate By similarity
Binding sitei160 – 1601Substrate By similarity
Binding sitei167 – 1671Substrate By similarity
Binding sitei191 – 1911Substrate By similarity
Binding sitei243 – 2431Substrate By similarity
Binding sitei261 – 2611Substrate; via amide nitrogen By similarity

GO - Molecular functioni

  1. glutaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciRLEG395492:GJB3-1977-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutaminase (EC:3.5.1.2)
Gene namesi
Name:glsA
Ordered Locus Names:Rleg2_1946
OrganismiRhizobium leguminosarum bv. trifolii (strain WSM2304)
Taxonomic identifieri395492 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium
ProteomesiUP000008330: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 309309GlutaminaseUniRule annotation
PRO_1000115702Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi395492.Rleg2_1946.

Structurei

3D structure databases

ProteinModelPortaliB5ZRF0.

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OMAiQRARRIN.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

B5ZRF0-1 [UniParc]FASTAAdd to Basket

« Hide

MADLQAILDS IHTDILPRIG EGKVADYIPE LAKVDPRQFG MAIVTVDGKV    50
YRVGDADIAF SIQSISKVFM LTLALGKVGE SLWKRVGREP SGSAFNSIVQ 100
LEHEGGIPRN PFINAGAIAV SDVVMAGHAP REAIGELLRF VRYLADDESI 150
TIDDKVARSE TQTGYRNVAL ANFMRAYRNL DHPVDHVLGV YFHQCALSMS 200
CEQLARAGLF LAARGSNPMT GHSVVSPKRA RRINALMLTC GHYDGSGDFA 250
YHVGLPGKSG VGGGIFAVAP GIASIAVWSP GLNKVGNSQL GAVALEMLAA 300
RTGWSVFGD 309
Length:309
Mass (Da):32,977
Last modified:November 25, 2008 - v1
Checksum:i43F3D00A335F9516
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001191 Genomic DNA. Translation: ACI55231.1.
RefSeqiWP_003586217.1. NC_011369.1.
YP_002281457.1. NC_011369.1.

Genome annotation databases

EnsemblBacteriaiACI55231; ACI55231; Rleg2_1946.
GeneIDi6980685.
KEGGirlt:Rleg2_1946.
PATRICi23127942. VBIRhiLeg95088_3793.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001191 Genomic DNA. Translation: ACI55231.1 .
RefSeqi WP_003586217.1. NC_011369.1.
YP_002281457.1. NC_011369.1.

3D structure databases

ProteinModelPortali B5ZRF0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 395492.Rleg2_1946.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACI55231 ; ACI55231 ; Rleg2_1946 .
GeneIDi 6980685.
KEGGi rlt:Rleg2_1946.
PATRICi 23127942. VBIRhiLeg95088_3793.

Phylogenomic databases

eggNOGi COG2066.
HOGENOMi HOG000216890.
KOi K01425.
OMAi QRARRIN.
OrthoDBi EOG6N94BK.

Enzyme and pathway databases

BioCyci RLEG395492:GJB3-1977-MONOMER.

Family and domain databases

Gene3Di 3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome of Rhizobium leguminosarum bv. trifolii WSM2304."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Yates R.
    , Ardley J., Tiwari R.P., O'Hara G., Howieson J., Brau L., Reeve W.
    Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: WSM2304.

Entry informationi

Entry nameiGLSA_RHILW
AccessioniPrimary (citable) accession number: B5ZRF0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: November 25, 2008
Last modified: September 3, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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