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Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Rhizobium leguminosarum bv. trifolii (strain WSM2304)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate.UniRule annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Phosphoglycerate kinase (pgk)
  3. 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (gpmA)
  4. Enolase (eno)
  5. Pyruvate kinase (Rleg2_3289)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei38SubstrateUniRule annotation1
Binding sitei120SubstrateUniRule annotation1
Binding sitei153SubstrateUniRule annotation1
Binding sitei203ATPUniRule annotation1
Binding sitei325ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi355 – 358ATPUniRule annotation4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
Biological processGlycolysis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00109; UER00185

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
Gene namesi
Name:pgkUniRule annotation
Ordered Locus Names:Rleg2_3241
OrganismiRhizobium leguminosarum bv. trifolii (strain WSM2304)
Taxonomic identifieri395492 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium
Proteomesi
  • UP000008330 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002033471 – 400Phosphoglycerate kinaseAdd BLAST400

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi395492.Rleg2_3241

Structurei

3D structure databases

ProteinModelPortaliB5ZPA0
SMRiB5ZPA0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni23 – 25Substrate bindingUniRule annotation3
Regioni61 – 64Substrate bindingUniRule annotation4

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105BZA Bacteria
COG0126 LUCA
HOGENOMiHOG000227107
KOiK00927
OMAiDMIFDIG

Family and domain databases

Gene3Di3.40.50.1260, 3 hits
HAMAPiMF_00145 Phosphoglyc_kinase, 1 hit
InterProiView protein in InterPro
IPR001576 Phosphoglycerate_kinase
IPR015911 Phosphoglycerate_kinase_CS
IPR015824 Phosphoglycerate_kinase_N
IPR036043 Phosphoglycerate_kinase_sf
PANTHERiPTHR11406 PTHR11406, 1 hit
PfamiView protein in Pfam
PF00162 PGK, 1 hit
PIRSFiPIRSF000724 Pgk, 1 hit
PRINTSiPR00477 PHGLYCKINASE
SUPFAMiSSF53748 SSF53748, 1 hit
PROSITEiView protein in PROSITE
PS00111 PGLYCERATE_KINASE, 1 hit

Sequencei

Sequence statusi: Complete.

B5ZPA0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPSFKTLDDL SDIRGKRVLV RVDLNVPVKD GKVTDTTRIE RVAPTILELS
60 70 80 90 100
EKGAKVILLA HFGRPKDGPS PELSLSLIAP SVEEVLDHAV STASDCIGEA
110 120 130 140 150
AASAVAAMND GDILLLENTR FHKGEEKNDP DFTKALAANG DIYVNDAFSA
160 170 180 190 200
AHRAHASTEG LAHHLPAYAG RTMQAELEAL EKGLGDPARP VVAIVGGAKV
210 220 230 240 250
STKIDLLMNL VKKVDALVIG GGMANTFIAA RGTNVGKSLC EHDLAETARQ
260 270 280 290 300
IMIEAATSGC AIILPEDGVI AREFKAGAAN ETVDIDAIPA DAMVLDVGPK
310 320 330 340 350
SVQAISAWIE RASTLVWNGP LGAFEIEPFD AATVGAAKYA AERTTAGKLT
360 370 380 390 400
SVAGGGDTVS ALNHAGVADD FTYVSTAGGA FLEWMEGKEL PGVAVLNAAR
Length:400
Mass (Da):41,651
Last modified:November 25, 2008 - v1
Checksum:i5C4EB077D6431AB0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001191 Genomic DNA Translation: ACI56508.1
RefSeqiWP_012558867.1, NC_011369.1

Genome annotation databases

EnsemblBacteriaiACI56508; ACI56508; Rleg2_3241
GeneIDi34194238
KEGGirlt:Rleg2_3241

Similar proteinsi

Entry informationi

Entry nameiPGK_RHILW
AccessioniPrimary (citable) accession number: B5ZPA0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: November 25, 2008
Last modified: May 23, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health