B5ZMN6 (UREF_RHILW) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Urease accessory protein UreF

Gene names

Name:	ureF
Ordered Locus Names:	Rleg2_3047

Organism

Rhizobium leguminosarum bv. trifolii (strain WSM2304) [Complete proteome] [HAMAP]

Taxonomic identifier

395492 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Rhizobium

Protein attributes

Sequence length	223 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter By similarity. HAMAP MF_01385
Subunit structure	UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel By similarity.
Subcellular location	Cytoplasm By similarity HAMAP MF_01385.
Sequence similarities	Belongs to the UreF family.

Ontologies

Keywords
Biological process	Nickel insertion
Cellular component	Cytoplasm
Molecular function	Chaperone
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	nickel cation binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 223	223	Urease accessory protein UreF HAMAP MF_01385		PRO_1000145138

Sequences

	Sequence		Length	Mass (Da)
	B5ZMN6 [UniParc]. Last modified November 25, 2008. Version 1. Checksum: 5F71F927FC4AE378	FASTA	223	23,423
	10 20 30 40 50 60 MTGDRELQAL LRLTAWLSPA FPVGSFAYSG GLERAVADGL VTDAVSLAAW IGTLIGYGSV 70 80 90 100 110 120 WNDAVLLAES HRWQAEPARL FEIAALAEAL AGSRERHQET MLLGDAFLTA ARAWPDGVFE 130 140 150 160 170 180 RLPDKAAYPV AVGAVTGAHG IGPEKALAVF LHAYASQAVS SGIRLGVTGQ RDGVAVLAGL 190 200 210 220 EECITEVARR AAASTLDDLG SATVQADIAG LRHETQATRL FRS

References

[1]

"Complete sequence of chromosome of Rhizobium leguminosarum bv. trifolii WSM2304." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Yates R. , Ardley J., Tiwari R.P., O'Hara G., Howieson J., Brau L., Reeve W. Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: WSM2304.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001191 Genomic DNA. Translation: ACI56314.1.
RefSeq	YP_002282540.1. NC_011369.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B5ZMN6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6981792.
GenomeReviews	Gene locus Rleg2_3047 in contig CP001191_GR.
KEGG	rlt:Rleg2_3047.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG709295.
OMA	WLSPAFP.
ProtClustDB	CLSK2486785.
Family and domain databases
HAMAP	MF_01385. UreF. [Tree]
InterPro	IPR002639. UreF. [Graphical view]
KO	K03188.
Pfam	PF01730. UreF. 1 hit. [Graphical view]
PIRSF	PIRSF009467. Ureas_acces_UreF. 1 hit.
ProtoNet	Search...

Entry information

Entry name

UREF_RHILW

Accession

Primary (citable) accession number: B5ZMN6

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	November 25, 2008
Last modified:	November 16, 2011
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program