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B5ZMF2 (SYR_RHILW) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:Rleg2_1482
OrganismRhizobium leguminosarum bv. trifolii (strain WSM2304) [Complete proteome] [HAMAP]
Taxonomic identifier395492 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium

Protein attributes

Sequence length585 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 585585Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000095397

Regions

Motif131 – 14111"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
B5ZMF2 [UniParc].

Last modified November 25, 2008. Version 1.
Checksum: 24C8EA29D6D884D3

FASTA58564,760
        10         20         30         40         50         60 
MNLFTDFEAR IKTALEQIDL VREKRSELDF GRIAVEPPRD ASHGDVATNA AMVLAKPLGT 

        70         80         90        100        110        120 
NPRALADIII AKLREDADVA DVSVAGPGFI NIRLAVGYWQ RLLAAMIGAG TDYGRSTLGE 

       130        140        150        160        170        180 
GRKVNVEYVS ANPTGPMHVG HCRGAVVGDA LANLLAFAGY GVEKEYYIND AGSQIDVLAR 

       190        200        210        220        230        240 
SVFLRYREAL GEKIGEIPSG LYPGDYLVPV GQSLAADYGV RLHNMPEDQW MPIVKDRTID 

       250        260        270        280        290        300 
AMMVMIREDL ASLNVHHDIF FSERTLHANG AAAIRTAIND LTFKGYVYKG TLPPPKGQLP 

       310        320        330        340        350        360 
EDWEDREQTL FRSTEVGDDM DRPLIKSDGS YTYFAADVAY FKNKFDRGFD EMIYVLGADH 

       370        380        390        400        410        420 
GGYVKRLEAV ARGVSDGKAK LTVLLCQLVK LYRNGEPVKM SKRSGDFVTL RDVVEEVGSD 

       430        440        450        460        470        480 
SVRFMMLYRK NSEPLDFDFA KVTEQSKDNP VFYVQYAHAR CMSVFRQARE AFGDLDVSPE 

       490        500        510        520        530        540 
EFAQTVAGIG DPAELQLVAK LAEFPRIVEA AAQSQEPHRL AFYLYDLASS FHAHWNKGKD 

       550        560        570        580 
QPELRFVNDK NRESTIARLG LVYAVASVLK SGLAITGTAA PDEMR 

« Hide

References

[1]"Complete sequence of chromosome of Rhizobium leguminosarum bv. trifolii WSM2304."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Yates R. expand/collapse author list , Ardley J., Tiwari R.P., O'Hara G., Howieson J., Brau L., Reeve W.
Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: WSM2304.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001191 Genomic DNA. Translation: ACI54774.1.
RefSeqYP_002281000.1. NC_011369.1.

3D structure databases

ProteinModelPortalB5ZMF2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING395492.Rleg2_1482.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACI54774; ACI54774; Rleg2_1482.
GeneID6980212.
KEGGrlt:Rleg2_1482.
PATRIC23126932. VBIRhiLeg95088_3297.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMAMEHMGFG.
OrthoDBEOG6JB13C.

Enzyme and pathway databases

BioCycRETL1328306-WGS:GSTH-1867-MONOMER.
RLEG395492:GJB3-1503-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_RHILW
AccessionPrimary (citable) accession number: B5ZMF2
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: November 25, 2008
Last modified: July 9, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries