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B5ZCB8 (RNPA_UREU1) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribonuclease P protein component

Short name=RNase P protein
Short name=RNaseP protein
EC=3.1.26.5
Alternative name(s):
Protein C5
Gene names
Name:rnpA
Ordered Locus Names:UUR10_0708
OrganismUreaplasma urealyticum serovar 10 (strain ATCC 33699 / Western) [Complete proteome] [HAMAP]
Taxonomic identifier565575 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesMycoplasmataceaeUreaplasma

Protein attributes

Sequence length118 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme By similarity. HAMAP-Rule MF_00227

Catalytic activity

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP-Rule MF_00227

Subunit structure

Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit By similarity.

Sequence similarities

Belongs to the RnpA family.

Ontologies

Keywords
   Biological processtRNA processing
   LigandRNA-binding
   Molecular functionEndonuclease
Hydrolase
Nuclease
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtRNA processing

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionribonuclease P activity

Inferred from electronic annotation. Source: UniProtKB-EC

tRNA binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 118118Ribonuclease P protein component HAMAP-Rule MF_00227
PRO_1000100406

Sequences

Sequence LengthMass (Da)Tools
B5ZCB8 [UniParc].

Last modified November 25, 2008. Version 1.
Checksum: 1D6B3F39344668C7

FASTA11813,792
        10         20         30         40         50         60 
MANFISLKRN EDILNIIKKQ QKIHSNHIVV YFCETNLKKV RLAISISKKK FKLATQRNRI 

        70         80         90        100        110 
RRLIKAWFIA ANVLVESYDI VVLVKPSFID GSFVLNCDNI KKILQTIISK HKQNKINK 

« Hide

References

[1]"Genome sequence of Ureaplasma urealyticum serovar 10 ATCC-33699."
Shrivastava S., Methe B.A., Glass J., White K., Duffy L.B.
Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 33699 / Western.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001184 Genomic DNA. Translation: ACI60017.1.
RefSeqYP_002285058.1. NC_011374.1.

3D structure databases

ProteinModelPortalB5ZCB8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING565575.UUR10_0708.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACI60017; ACI60017; UUR10_0708.
GeneID6983906.
KEGGuue:UUR10_0708.
PATRIC20536272. VBIUreUre98799_0676.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0594.
HOGENOMHOG000052712.
KOK03536.
OMAAWFIAAN.
OrthoDBEOG654P5P.
ProtClustDBCLSK2299007.

Enzyme and pathway databases

BioCycUURE565575:GBZS-694-MONOMER.

Family and domain databases

Gene3D3.30.230.10. 1 hit.
HAMAPMF_00227. RNase_P.
InterProIPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR000100. RNase_P.
IPR020539. RNase_P_CS.
[Graphical view]
PfamPF00825. Ribonuclease_P. 1 hit.
[Graphical view]
ProDomPD003629. Ribonuclease_P. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF54211. SSF54211. 1 hit.
TIGRFAMsTIGR00188. rnpA. 1 hit.
PROSITEPS00648. RIBONUCLEASE_P. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRNPA_UREU1
AccessionPrimary (citable) accession number: B5ZCB8
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: November 25, 2008
Last modified: April 16, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families