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B5ZCB8

- RNPA_UREU1

UniProt

B5ZCB8 - RNPA_UREU1

Protein

Ribonuclease P protein component

Gene

rnpA

Organism
Ureaplasma urealyticum serovar 10 (strain ATCC 33699 / Western)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
  1. Functioni

    RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.UniRule annotation

    Catalytic activityi

    Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

    GO - Molecular functioni

    1. ribonuclease P activity Source: UniProtKB-EC
    2. tRNA binding Source: InterPro

    GO - Biological processi

    1. tRNA processing Source: UniProtKB-KW

    Keywords - Molecular functioni

    Endonuclease, Hydrolase, Nuclease

    Keywords - Biological processi

    tRNA processing

    Keywords - Ligandi

    RNA-binding

    Enzyme and pathway databases

    BioCyciUURE565575:GBZS-694-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ribonuclease P protein componentUniRule annotation (EC:3.1.26.5UniRule annotation)
    Short name:
    RNase P proteinUniRule annotation
    Short name:
    RNaseP proteinUniRule annotation
    Alternative name(s):
    Protein C5UniRule annotation
    Gene namesi
    Name:rnpAUniRule annotation
    Ordered Locus Names:UUR10_0708
    OrganismiUreaplasma urealyticum serovar 10 (strain ATCC 33699 / Western)
    Taxonomic identifieri565575 [NCBI]
    Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeUreaplasma
    ProteomesiUP000002018: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 118118Ribonuclease P protein componentPRO_1000100406Add
    BLAST

    Interactioni

    Subunit structurei

    Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.UniRule annotation

    Protein-protein interaction databases

    STRINGi565575.UUR10_0708.

    Structurei

    3D structure databases

    ProteinModelPortaliB5ZCB8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the RnpA family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0594.
    HOGENOMiHOG000052712.
    KOiK03536.
    OMAiQNRAREW.
    OrthoDBiEOG654P5P.

    Family and domain databases

    Gene3Di3.30.230.10. 1 hit.
    HAMAPiMF_00227. RNase_P.
    InterProiIPR020568. Ribosomal_S5_D2-typ_fold.
    IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
    IPR000100. RNase_P.
    IPR020539. RNase_P_CS.
    [Graphical view]
    PfamiPF00825. Ribonuclease_P. 1 hit.
    [Graphical view]
    ProDomiPD003629. Ribonuclease_P. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    SUPFAMiSSF54211. SSF54211. 1 hit.
    TIGRFAMsiTIGR00188. rnpA. 1 hit.
    PROSITEiPS00648. RIBONUCLEASE_P. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B5ZCB8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MANFISLKRN EDILNIIKKQ QKIHSNHIVV YFCETNLKKV RLAISISKKK    50
    FKLATQRNRI RRLIKAWFIA ANVLVESYDI VVLVKPSFID GSFVLNCDNI 100
    KKILQTIISK HKQNKINK 118
    Length:118
    Mass (Da):13,792
    Last modified:November 25, 2008 - v1
    Checksum:i1D6B3F39344668C7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001184 Genomic DNA. Translation: ACI60017.1.
    RefSeqiYP_002285058.1. NC_011374.1.

    Genome annotation databases

    EnsemblBacteriaiACI60017; ACI60017; UUR10_0708.
    GeneIDi6983906.
    KEGGiuue:UUR10_0708.
    PATRICi20536272. VBIUreUre98799_0676.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001184 Genomic DNA. Translation: ACI60017.1 .
    RefSeqi YP_002285058.1. NC_011374.1.

    3D structure databases

    ProteinModelPortali B5ZCB8.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 565575.UUR10_0708.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACI60017 ; ACI60017 ; UUR10_0708 .
    GeneIDi 6983906.
    KEGGi uue:UUR10_0708.
    PATRICi 20536272. VBIUreUre98799_0676.

    Phylogenomic databases

    eggNOGi COG0594.
    HOGENOMi HOG000052712.
    KOi K03536.
    OMAi QNRAREW.
    OrthoDBi EOG654P5P.

    Enzyme and pathway databases

    BioCyci UURE565575:GBZS-694-MONOMER.

    Family and domain databases

    Gene3Di 3.30.230.10. 1 hit.
    HAMAPi MF_00227. RNase_P.
    InterProi IPR020568. Ribosomal_S5_D2-typ_fold.
    IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
    IPR000100. RNase_P.
    IPR020539. RNase_P_CS.
    [Graphical view ]
    Pfami PF00825. Ribonuclease_P. 1 hit.
    [Graphical view ]
    ProDomi PD003629. Ribonuclease_P. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    SUPFAMi SSF54211. SSF54211. 1 hit.
    TIGRFAMsi TIGR00188. rnpA. 1 hit.
    PROSITEi PS00648. RIBONUCLEASE_P. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of Ureaplasma urealyticum serovar 10 ATCC-33699."
      Shrivastava S., Methe B.A., Glass J., White K., Duffy L.B.
      Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 33699 / Western.

    Entry informationi

    Entry nameiRNPA_UREU1
    AccessioniPrimary (citable) accession number: B5ZCB8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 24, 2009
    Last sequence update: November 25, 2008
    Last modified: October 1, 2014
    This is version 44 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3