Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Methionyl-tRNA formyltransferase

Gene

fmt

Organism
Ureaplasma urealyticum serovar 10 (strain ATCC 33699 / Western)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.UniRule annotation

Catalytic activityi

10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = tetrahydrofolate + N-formylmethionyl-tRNA(fMet).UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionTransferase
Biological processProtein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Methionyl-tRNA formyltransferaseUniRule annotation (EC:2.1.2.9UniRule annotation)
Gene namesi
Name:fmtUniRule annotation
Ordered Locus Names:UUR10_0508
OrganismiUreaplasma urealyticum serovar 10 (strain ATCC 33699 / Western)
Taxonomic identifieri565575 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeUreaplasma
Proteomesi
  • UP000002018 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000984581 – 305Methionyl-tRNA formyltransferaseAdd BLAST305

Interactioni

Protein-protein interaction databases

STRINGi565575.UUR10_0508

Structurei

3D structure databases

ProteinModelPortaliB5ZBV9
SMRiB5ZBV9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni110 – 113Tetrahydrofolate (THF) bindingUniRule annotation4

Sequence similaritiesi

Belongs to the Fmt family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CAE Bacteria
COG0223 LUCA
HOGENOMiHOG000261177
KOiK00604
OMAiLRIVFMG

Family and domain databases

Gene3Di3.10.25.10, 1 hit
HAMAPiMF_00182 Formyl_trans, 1 hit
InterProiView protein in InterPro
IPR005794 Fmt
IPR005793 Formyl_trans_C
IPR037022 Formyl_trans_C_sf
IPR002376 Formyl_transf_N
IPR036477 Formyl_transf_N_sf
IPR011034 Formyl_transferase-like_C_sf
PfamiView protein in Pfam
PF02911 Formyl_trans_C, 1 hit
PF00551 Formyl_trans_N, 1 hit
SUPFAMiSSF50486 SSF50486, 1 hit
SSF53328 SSF53328, 1 hit
TIGRFAMsiTIGR00460 fmt, 1 hit

Sequencei

Sequence statusi: Complete.

B5ZBV9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKYNVMFFGT PEIAKIVLET LFNMPEVNLI GVVSQPDSHF DRKKNVVYSP
60 70 80 90 100
VKQFCLDHDI KLFQPQKIKE IEEEIRSLAP DIIITCAFGQ FINQGIIDIP
110 120 130 140 150
KYKIVNVHAS LLPKLRGGAP IHYAILNGDL QTGITLMHTI KKMDAGNILF
160 170 180 190 200
QRSLAINEQT TTKILTLELA NLGALMIKEH FLELVKSDLV GIQQDENDVS
210 220 230 240 250
FAYNIQKNQN IIDFNKPAFF VNRFVNAMYD KPIAIMEYND VLIKVHQIKI
260 270 280 290 300
TNQKSTQKPG TIAISKHQIF VSTQDFNVEL LLIQLPNKKP LAPKALLNGK

NPFSN
Length:305
Mass (Da):34,555
Last modified:November 25, 2008 - v1
Checksum:i267789686F7ADD6D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001184 Genomic DNA Translation: ACI59933.1
RefSeqiWP_004025631.1, NC_011374.1

Genome annotation databases

EnsemblBacteriaiACI59933; ACI59933; UUR10_0508
KEGGiuue:UUR10_0508

Similar proteinsi

Entry informationi

Entry nameiFMT_UREU1
AccessioniPrimary (citable) accession number: B5ZBV9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: November 25, 2008
Last modified: March 28, 2018
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health