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Protein

Urease subunit gamma

Gene

ureA

Organism
Ureaplasma urealyticum serovar 10 (strain ATCC 33699 / Western)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Urea + H2O = CO2 + 2 NH3.UniRule annotation

Pathwayi: urea degradation

This protein is involved in step 1 of the subpathway that synthesizes CO(2) and NH(3) from urea (urease route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Urease subunit beta (ureB), Urease subunit alpha (ureC), Urease subunit gamma (ureA)
This subpathway is part of the pathway urea degradation, which is itself part of Nitrogen metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes CO(2) and NH(3) from urea (urease route), the pathway urea degradation and in Nitrogen metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciUURE565575:GBZS-478-MONOMER.
UniPathwayiUPA00258; UER00370.

Names & Taxonomyi

Protein namesi
Recommended name:
Urease subunit gammaUniRule annotation (EC:3.5.1.5UniRule annotation)
Alternative name(s):
Urea amidohydrolase subunit gammaUniRule annotation
Gene namesi
Name:ureAUniRule annotation
Ordered Locus Names:UUR10_0479
OrganismiUreaplasma urealyticum serovar 10 (strain ATCC 33699 / Western)
Taxonomic identifieri565575 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeUreaplasma
Proteomesi
  • UP000002018 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 101101Urease subunit gammaPRO_1000199888Add
BLAST

Interactioni

Subunit structurei

Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.UniRule annotation

Protein-protein interaction databases

STRINGi565575.UUR10_0479.

Structurei

3D structure databases

ProteinModelPortaliB5ZBT1.
SMRiB5ZBT1. Positions 1-99.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the urease gamma subunit family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108YZ9. Bacteria.
COG0831. LUCA.
HOGENOMiHOG000075053.
KOiK01430.
OMAiELMSYGT.
OrthoDBiEOG69PQ9G.

Family and domain databases

Gene3Di3.30.280.10. 1 hit.
HAMAPiMF_00739. Urease_gamma.
InterProiIPR012010. Urease_gamma.
IPR002026. Urease_gamma/gamma-beta_su.
[Graphical view]
PfamiPF00547. Urease_gamma. 1 hit.
[Graphical view]
PIRSFiPIRSF001223. Urease_gamma. 1 hit.
ProDomiPD002319. Urease_gamma_reg. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF54111. SSF54111. 1 hit.
TIGRFAMsiTIGR00193. urease_gam. 1 hit.

Sequencei

Sequence statusi: Complete.

B5ZBT1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLSLREIQK LLVTVAADVA RRRLARGLKL NYSEAVALIT DHVVEGARDG
60 70 80 90 100
KLVADLMQSA REVLRVDQVM EGVDTMVGII QVEVTFPDGT KLVSVHDPIY

K
Length:101
Mass (Da):11,157
Last modified:November 25, 2008 - v1
Checksum:iE93D1FCD858C9F12
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF085726 Genomic DNA. Translation: AAD28122.1.
CP001184 Genomic DNA. Translation: ACI60150.1.
RefSeqiWP_004026214.1. NC_011374.1.

Genome annotation databases

EnsemblBacteriaiACI60150; ACI60150; UUR10_0479.
KEGGiuue:UUR10_0479.
PATRICi20535808. VBIUreUre98799_0465.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF085726 Genomic DNA. Translation: AAD28122.1.
CP001184 Genomic DNA. Translation: ACI60150.1.
RefSeqiWP_004026214.1. NC_011374.1.

3D structure databases

ProteinModelPortaliB5ZBT1.
SMRiB5ZBT1. Positions 1-99.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi565575.UUR10_0479.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACI60150; ACI60150; UUR10_0479.
KEGGiuue:UUR10_0479.
PATRICi20535808. VBIUreUre98799_0465.

Phylogenomic databases

eggNOGiENOG4108YZ9. Bacteria.
COG0831. LUCA.
HOGENOMiHOG000075053.
KOiK01430.
OMAiELMSYGT.
OrthoDBiEOG69PQ9G.

Enzyme and pathway databases

UniPathwayiUPA00258; UER00370.
BioCyciUURE565575:GBZS-478-MONOMER.

Family and domain databases

Gene3Di3.30.280.10. 1 hit.
HAMAPiMF_00739. Urease_gamma.
InterProiIPR012010. Urease_gamma.
IPR002026. Urease_gamma/gamma-beta_su.
[Graphical view]
PfamiPF00547. Urease_gamma. 1 hit.
[Graphical view]
PIRSFiPIRSF001223. Urease_gamma. 1 hit.
ProDomiPD002319. Urease_gamma_reg. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF54111. SSF54111. 1 hit.
TIGRFAMsiTIGR00193. urease_gam. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Phylogenetic analysis of Ureaplasma urealyticum -- support for the establishment of a new species, Ureaplasma parvum."
    Kong F., James G., Ma Z., Gordon S., Wang B., Gilbert G.L.
    Int. J. Syst. Bacteriol. 49:1879-1889(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Genome sequence of Ureaplasma urealyticum serovar 10 ATCC-33699."
    Shrivastava S., Methe B.A., Glass J., White K., Duffy L.B.
    Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33699 / Western.

Entry informationi

Entry nameiURE3_UREU1
AccessioniPrimary (citable) accession number: B5ZBT1
Secondary accession number(s): P17274, Q9R2R9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: November 25, 2008
Last modified: December 9, 2015
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.