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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Helicobacter pylori (strain G27)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei156GTPUniRule annotation1
Binding sitei160GTPUniRule annotation1
Binding sitei204GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi37 – 41GTPUniRule annotation5
Nucleotide bindingi125 – 127GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotationImported
Ordered Locus Names:HPG27_926Imported
OrganismiHelicobacter pylori (strain G27)Imported
Taxonomic identifieri563041 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
Proteomesi
  • UP000001735 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini29 – 222TubulinInterPro annotationAdd BLAST194
Domaini224 – 343Tubulin_CInterPro annotationAdd BLAST120

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000049094.
KOiK03531.
OMAiMRAVKGI.
OrthoDBiPOG091H02KK.

Family and domain databases

CDDicd02201. FtsZ_type1. 1 hit.
Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
HAMAPiMF_00909. FtsZ. 1 hit.
InterProiView protein in InterPro
IPR000158. Cell_div_FtsZ.
IPR020805. Cell_div_FtsZ_CS.
IPR024757. FtsZ_C.
IPR008280. Tub_FtsZ_C.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR003008. Tubulin_FtsZ_GTPase.
PfamiView protein in Pfam
PF12327. FtsZ_C. 1 hit.
PF00091. Tubulin. 1 hit.
PRINTSiPR00423. CELLDVISFTSZ.
SMARTiView protein in SMART
SM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
TIGRFAMsiTIGR00065. ftsZ. 1 hit.
PROSITEiView protein in PROSITE
PS01134. FTSZ_1. 1 hit.
PS01135. FTSZ_2. 1 hit.

Sequencei

Sequence statusi: Complete.

B5Z7Y1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVHQSEMENY NIGQASIEEV SDPAYKGAKI VVIGVGGGGS NMIKHLVEYG
60 70 80 90 100
VHQDVTPIAT NTDGQHLKNN PAPVKILLGK ESTGGLGAGG VPDIGRKAAE
110 120 130 140 150
ESANEIREAI KDAKLVIVST GLGGGTGTGA TPTIVKIAKE VGALTIAIVT
160 170 180 190 200
KPFKYEGSQK SKKAEEGLKE LEQSSDSILV IPNDKILLTM KKNASTKECY
210 220 230 240 250
KEVDDVLVRA VSGISTIITK PGDINVDFSD LKSALGFKGF ALMGIGEATG
260 270 280 290 300
EESAKLAVEN AIQSPLLDDA SIDGAKSIIV FFEHHPDYPM YAYSQACISI
310 320 330 340 350
QERANQDVDV KFGQHTSESI PIDHVRVTII ATGAERNSGG AGLESIATPS
360 370 380
QPVVKQTRKV GNSDFLRIPT EEELSTPTAI RIQQD
Length:385
Mass (Da):40,747
Last modified:November 25, 2008 - v1
Checksum:i633ABA6A9381EBB6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001173 Genomic DNA. Translation: ACI27680.1.
RefSeqiWP_000233623.1. NC_011333.1.

Genome annotation databases

EnsemblBacteriaiACI27680; ACI27680; HPG27_926.
KEGGihpg:HPG27_926.

Similar proteinsi

Entry informationi

Entry nameiB5Z7Y1_HELPG
AccessioniPrimary (citable) accession number: B5Z7Y1
Entry historyiIntegrated into UniProtKB/TrEMBL: November 25, 2008
Last sequence update: November 25, 2008
Last modified: September 27, 2017
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported