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Protein

Transcription termination factor Rho

Gene

rho

Organism
Helicobacter pylori (strain G27)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.UniRule annotation

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei231ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi188 – 193ATPUniRule annotation6
Nucleotide bindingi200 – 205ATPUniRule annotation6

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHelicaseUniRule annotation, Hydrolase, RNA-bindingUniRule annotation
Biological processTranscription, Transcription regulation, Transcription terminationUniRule annotation
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription termination factor RhoUniRule annotation (EC:3.6.4.-UniRule annotation)
Alternative name(s):
ATP-dependent helicase RhoUniRule annotation
Gene namesi
Name:rhoUniRule annotation
Ordered Locus Names:HPG27_510Imported
OrganismiHelicobacter pylori (strain G27)Imported
Taxonomic identifieri563041 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
Proteomesi
  • UP000001735 Componenti: Chromosome

Interactioni

Subunit structurei

Homohexamer. The homohexamer assembles into an open ring structure.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB5Z6S3
SMRiB5Z6S3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini27 – 69Rho_NInterPro annotationAdd BLAST43
Domaini74 – 140CSPInterPro annotationAdd BLAST67
Domaini189 – 380AAAInterPro annotationAdd BLAST192

Sequence similaritiesi

Belongs to the Rho family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000076952
KOiK03628
OMAiDYNYLPG
OrthoDBiPOG091H05EO

Family and domain databases

CDDicd04459 Rho_CSD, 1 hit
HAMAPiMF_01884 Rho, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR000194 ATPase_F1/V1/A1_a/bsu_nucl-bd
IPR011129 CSD
IPR012340 NA-bd_OB-fold
IPR027417 P-loop_NTPase
IPR011112 Rho_N
IPR036269 Rho_N_sf
IPR011113 Rho_RNA-bd
IPR004665 Term_rho
PANTHERiPTHR15184:SF34 PTHR15184:SF34, 1 hit
PfamiView protein in Pfam
PF00006 ATP-synt_ab, 1 hit
PF07498 Rho_N, 1 hit
PF07497 Rho_RNA_bind, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SM00357 CSP, 1 hit
SM00959 Rho_N, 1 hit
SUPFAMiSSF50249 SSF50249, 1 hit
SSF52540 SSF52540, 1 hit
SSF68912 SSF68912, 1 hit
TIGRFAMsiTIGR00767 rho, 1 hit

Sequencei

Sequence statusi: Complete.

B5Z6S3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNENAPTHKS SHKVKTHTPV SGYHIEDLRT YPTEKLLEIA NKLKVENPQE
60 70 80 90 100
FKRQDLMFEI LKTQVTQGGY ILFTGILEIM PDGYGFLRGF DGSFSDGHND
110 120 130 140 150
TYVSPSQIRR FALRNGDIVT GQVRSPKDQE KYYALLKIEA INYLPSDEIK
160 170 180 190 200
NRPLFDNLTP LFPDEQIKLE YEPTKVTGRM LDLFSPVGKG QRALIVAPPR
210 220 230 240 250
TGKTELMKEL AQGITSNHPE VELIILLVDE RPEEVTDMQR SVKGQVFSST
260 270 280 290 300
FDLPANNHIR IAELVLERAK RRVEMGKDVV VLLDSITRLA RAYNAVTPSS
310 320 330 340 350
GKVLSGGVDA NALHRPKRFF GAARNIEEGG SLTIIATALI ETGSRMDEVI
360 370 380 390 400
FEEFKGTGNS EIVLARNIAD RRIYPAFDIL KSGTRKDNIL LGKDRLTKVW
410 420 430
VLRNVMQQMD DIEALSFVYS KMQQTKDNEE FLNLMNEK
Length:438
Mass (Da):49,545
Last modified:November 25, 2008 - v1
Checksum:iA383ADB7E65C8C98
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001173 Genomic DNA Translation: ACI27272.1
RefSeqiWP_001004709.1, NC_011333.1

Genome annotation databases

EnsemblBacteriaiACI27272; ACI27272; HPG27_510
KEGGihpg:HPG27_510

Similar proteinsi

Entry informationi

Entry nameiB5Z6S3_HELPG
AccessioniPrimary (citable) accession number: B5Z6S3
Entry historyiIntegrated into UniProtKB/TrEMBL: November 25, 2008
Last sequence update: November 25, 2008
Last modified: October 25, 2017
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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