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B5Z4Q2 (RSMC_ECO5E) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribosomal RNA small subunit methyltransferase C
EC=2.1.1.172
Alternative name(s):
16S rRNA m2G1207 methyltransferase
rRNA (guanine-N(2)-)-methyltransferase RsmC
Gene names
Name:rsmC
Ordered Locus Names:ECH74115_5883
OrganismEscherichia coli O157:H7 (strain EC4115 / EHEC) [Complete proteome] [HAMAP]
Taxonomic identifier444450 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length343 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Specifically methylates the guanosine in position 1207 of 16S rRNA in the 30S particle By similarity. HAMAP MF_01862

Catalytic activity

S-adenosyl-L-methionine + guanosine(1207) in 16S rRNA = S-adenosyl-L-homocysteine + N(2)-methylguanosine(1207) in 16S rRNA. HAMAP MF_01862

Subunit structure

Monomer By similarity. HAMAP MF_01862

Subcellular location

Cytoplasm Potential HAMAP MF_01862.

Sequence similarities

Belongs to the methyltransferase superfamily. RsmC family.

Ontologies

Keywords
   Biological processrRNA processing
   Cellular componentCytoplasm
   LigandS-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionnucleic acid binding

Inferred from electronic annotation. Source: InterPro

rRNA (guanine-N2-)-methyltransferase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 343343Ribosomal RNA small subunit methyltransferase C HAMAP MF_01862
PRO_0000369706

Sequences

Sequence LengthMass (Da)Tools
B5Z4Q2 [UniParc].

Last modified November 25, 2008. Version 1.
Checksum: E145C3F11211D4A0

FASTA34337,602
        10         20         30         40         50         60 
MSAFTPASEV LLRHSDDFEQ SRILFAGDLQ DDLPARLDTA ASRAHTQQFQ HWQVLSRQMG 

        70         80         90        100        110        120 
DNARFSLVAT ADDVADCDTL IYYWPKNKPE AQFQLMNLLS LLPVGTDIFV VGENRSGVRS 

       130        140        150        160        170        180 
AEQMLADYAP LNKVDSARRC GLYFGRLEKQ PVFDADKFWG EYSVDGLTVK TLPGVFSRDG 

       190        200        210        220        230        240 
LDVGSQLLLS TLTPHTKGKV LDVGCGAGVL SVAFARHSPK IRLTLCDVSA PAVEASRATL 

       250        260        270        280        290        300 
AANGVEGEVF ASNVFSEVKG RFDMIISNPP FHDGMQTSLD AAQTLIRGAV RHLNSGGELR 

       310        320        330        340 
IVANAFLPYP DVLDETFGFH EVIAQTGRFK VYRAIMTRQA KKG

« Hide

References

[1]"Complete genome sequence of Escherichia coli O157:H7 str. EC4115."
Eppinger M., Sebastian Y., Ravel J.
Submitted (SEP-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: EC4115 / EHEC.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001164 Genomic DNA. Translation: ACI36990.1.
RefSeqYP_002273891.1. NC_011353.1.

3D structure databases

ProteinModelPortalB5Z4Q2.
SMRB5Z4Q2. Positions 3-336.
ModBaseSearch...

Protein-protein interaction databases

STRINGB5Z4Q2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBESCT00000031021; EBESCP00000029724; EBESCG00000030071.
GeneID6972339.
GenomeReviewsGene locus ECH74115_5883 in contig CP001164_GR.
KEGGecf:ECH74115_5883.
PATRIC18372275. VBIEscCol74651_5714.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000009812.
HOGENOMHBG296757.
OMATGKFKVY.
ProtClustDBPRK09489.

Family and domain databases

HAMAPMF_01862. 16SrRNA_methyltr_C.
[Tree]
InterProIPR002052. DNA_methylase_N6_adenine_CS.
IPR013675. Mtase_sm_N.
IPR023543. rRNA_ssu_MeTfrase_C.
IPR007848. Small_mtfrase.
[Graphical view]
KOK00564.
PfamPF05175. MTS. 1 hit.
PF08468. MTS_N. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRSMC_ECO5E
AccessionPrimary (citable) accession number: B5Z4Q2
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: November 25, 2008
Last modified: January 25, 2012
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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