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Protein
Submitted name:

Hypoxanthine phosphoribosyltransferase

Gene

hpt

Organism
Escherichia coli O157:H7 (strain EC4115 / EHEC)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. hypoxanthine phosphoribosyltransferase activity Source: InterPro

GO - Biological processi

  1. purine ribonucleoside salvage Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

GlycosyltransferaseImported, Transferase

Enzyme and pathway databases

BioCyciECOL444450:GHOB-130-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Hypoxanthine phosphoribosyltransferaseImported
Gene namesi
Name:hptImported
Ordered Locus Names:ECH74115_0133Imported
OrganismiEscherichia coli O157:H7 (strain EC4115 / EHEC)Imported
Taxonomic identifieri444450 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000001737: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: InterPro
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi444450.ECH74115_0133.

Structurei

3D structure databases

ProteinModelPortaliB5YZG1.
SMRiB5YZG1. Positions 1-177.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0634.
HOGENOMiHOG000236520.
KOiK00760.
OMAiTMDWMAV.
OrthoDBiEOG693GNP.

Family and domain databases

Gene3Di3.40.50.2020. 1 hit.
InterProiIPR005904. Hxn_phspho_trans.
IPR000836. PRibTrfase_dom.
IPR029057. PRTase-like.
[Graphical view]
PfamiPF00156. Pribosyltran. 1 hit.
[Graphical view]
SUPFAMiSSF53271. SSF53271. 1 hit.
TIGRFAMsiTIGR01203. HGPRTase. 1 hit.

Sequencei

Sequence statusi: Complete.

B5YZG1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKHTVEVMIP EAEIKARIAE LGRQITERYK DSGSDMVLVG LLRGSFMFMA
60 70 80 90 100
DLCREVQVSH EVDFMTASSY GSGMSTTRDV KILKDLDEDI RGKDVLIVED
110 120 130 140 150
IIDSGNTLSK VREILSLREP KSLAICTLLD KPSRREVNVP VEFIGFSIPD
160 170
EFVVGYGIDY AQRYRHLPYI GKVILLDE
Length:178
Mass (Da):20,115
Last modified:November 25, 2008 - v1
Checksum:iE1A75EB68231DC32
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001164 Genomic DNA. Translation: ACI39090.1.
RefSeqiYP_002268733.1. NC_011353.1.

Genome annotation databases

EnsemblBacteriaiACI39090; ACI39090; ECH74115_0133.
GeneIDi6972071.
KEGGiecf:ECH74115_0133.
PATRICi18361110. VBIEscCol74651_0270.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001164 Genomic DNA. Translation: ACI39090.1.
RefSeqiYP_002268733.1. NC_011353.1.

3D structure databases

ProteinModelPortaliB5YZG1.
SMRiB5YZG1. Positions 1-177.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi444450.ECH74115_0133.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACI39090; ACI39090; ECH74115_0133.
GeneIDi6972071.
KEGGiecf:ECH74115_0133.
PATRICi18361110. VBIEscCol74651_0270.

Phylogenomic databases

eggNOGiCOG0634.
HOGENOMiHOG000236520.
KOiK00760.
OMAiTMDWMAV.
OrthoDBiEOG693GNP.

Enzyme and pathway databases

BioCyciECOL444450:GHOB-130-MONOMER.

Family and domain databases

Gene3Di3.40.50.2020. 1 hit.
InterProiIPR005904. Hxn_phspho_trans.
IPR000836. PRibTrfase_dom.
IPR029057. PRTase-like.
[Graphical view]
PfamiPF00156. Pribosyltran. 1 hit.
[Graphical view]
SUPFAMiSSF53271. SSF53271. 1 hit.
TIGRFAMsiTIGR01203. HGPRTase. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: EC4115 / EHECImported.

Entry informationi

Entry nameiB5YZG1_ECO5E
AccessioniPrimary (citable) accession number: B5YZG1
Entry historyi
Integrated into UniProtKB/TrEMBL: November 25, 2008
Last sequence update: November 25, 2008
Last modified: January 7, 2015
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.