Reviewed, UniProtKB/Swiss-Prot B5YPM2 (ALLA_ECO5E)

Names and origin

Protein names

Recommended name:
    Ureidoglycolate hydrolase
    EC=3.5.3.19

Gene names

Name:	allA
Ordered Locus Names:	ECH74115_0606

Organism

Escherichia coli O157:H7 (strain EC4115 / EHEC) [Complete proteome] [HAMAP]

Taxonomic identifier

444450 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	160 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Involved in the anaerobic utilization of allantoin. Reinforces the induction of genes involved in the degradation of allantoin and glyoxylate by producing glyoxylate By similarity.
Catalytic activity	(S)-ureidoglycolate + H2O = glyoxylate + 2 NH3 + CO2. HAMAP MF_00616
Pathway	Nitrogen metabolism; (S)-allantoin degradation; glyoxylate from (S)-ureidoglycolate: step 1/1. HAMAP MF_00616
Subunit structure	Homodimer By similarity.
Sequence similarities	Belongs to the ureidoglycolate hydrolase family.

Ontologies

Keywords
Biological process	Purine metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	allantoin catabolic process Inferred from electronic annotation. Source: InterPro purine base catabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	ureidoglycolate hydrolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 160	160	Ureidoglycolate hydrolase HAMAP MF_00616		PRO_1000130412

Sequences

	Sequence		Length	Mass (Da)
	B5YPM2-1 [UniParc]. Last modified November 25, 2008. Version 1. Checksum: E39014610FE93FC6	FASTA	160	18,223
	10 20 30 40 50 60 MKLQVLPLSQ EAFSAYGDVI ETQQRDFFHI NNGLVERYHD LALVEILEQD RTLISINRAQ 70 80 90 100 110 120 PANLPLTIHE LERHPLGTQA FIPMKGEVFV VVVALGDDKP DLSTLRAFIT NGEQGVNYHR 130 140 150 160 NVWHHPLFAW QRVTDFLTID RGGSDNCDVE SIPEQELCFA

References

[1]	"Complete genome sequence of Escherichia coli O157:H7 str. EC4115." Eppinger M., Sebastian Y., Ravel J. Submitted (SEP-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP001164 Genomic DNA. Translation: ACI35520.1.
RefSeq	YP_002269160.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6967070.
GenomeReviews	Gene locus ECH74115_0606 in contig CP001164_GR.
KEGG	ecf:ECH74115_0606.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	YRAGTWH.
Family and domain databases
HAMAP	MF_00616. [Tree]
InterPro	IPR007247. Ureidogly_hydro. [Graphical view]
PANTHER	PTHR21221. Ureidogly_hydro. 1 hit.
Pfam	PF04115. Ureidogly_hydro. 1 hit. [Graphical view]
PIRSF	PIRSF017306. Ureidogly_hydro. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ALLA_ECO5E

Accession

Primary (citable) accession number: B5YPM2

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	November 25, 2008
Last modified:	November 3, 2009
This is version 11 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)