B5YKL4 (TRPF_THEYD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase
Short name=PRAI
EC=5.3.1.24

Gene names

Name:	trpF
Ordered Locus Names:	THEYE_A0943

Organism

Thermodesulfovibrio yellowstonii (strain ATCC 51303 / DSM 11347 / YP87) [Reference proteome] [HAMAP]

Taxonomic identifier

289376 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Nitrospirae › Nitrospira › Nitrospirales › Nitrospiraceae › Thermodesulfovibrio › Thermodesulfovibrio yellowstonii

Protein attributes

Sequence length	217 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. HAMAP-Rule MF_00135
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5. HAMAP-Rule MF_00135
Sequence similarities	Belongs to the TrpF family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis
Molecular function	Isomerase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	tryptophan biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	phosphoribosylanthranilate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 217	217	N-(5'-phosphoribosyl)anthranilate isomerase HAMAP-Rule MF_00135		PRO_1000095948

Sequences

	Sequence		Length	Mass (Da)
	B5YKL4 [UniParc]. Last modified November 25, 2008. Version 1. Checksum: BF4BCAEE76A5A0DA	FASTA	217	24,338
	10 20 30 40 50 60 MIRVKICGIT NIDDALWATE CGADALGFIF YKKSQRYIDP QKAKEIIKAL PPFVNLVGVF 70 80 90 100 110 120 VNETVENIKE IMAITGIDTV QLHGDETSEF CLNFRKVIKA FRVDNRGYLP NGKSLKDILP 130 140 150 160 170 180 KYKVSAFLLD SFSENEYGGT GKTFNWDVAL KAKEYGTIIL SGGLNVFNID EAIKKVFPYA 190 200 210 VDVSSGVELY KGKKDPELVK KFIEKAKLKK IKGEHDD

References

[1]

"The complete genome sequence of Thermodesulfovibrio yellowstonii strain ATCC 51303 / DSM 11347 / YP87." Dodson R.J., Durkin A.S., Wu M., Eisen J., Sutton G. Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51303 / DSM 11347 / YP87.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001147 Genomic DNA. Translation: ACI21048.1.
RefSeq	YP_002248779.1. NC_011296.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	289376.THEYE_A0943.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACI21048; ACI21048; THEYE_A0943.
GeneID	6943280.
KEGG	tye:THEYE_A0943.
PATRIC	23908907. VBITheYel104483_0929.
Phylogenomic databases
eggNOG	COG0135.
HOGENOM	HOG000161598.
KO	K01817.
OMA	PVIRAIQ.
Enzyme and pathway databases
UniPathway	UPA00035; UER00042.
Family and domain databases
Gene3D	3.20.20.70. 1 hit.
HAMAP	MF_00135. PRAI.
InterPro	IPR013785. Aldolase_TIM. IPR001240. PRAI. IPR011060. RibuloseP-bd_barrel. [Graphical view]
Pfam	PF00697. PRAI. 1 hit. [Graphical view]
SUPFAM	SSF51366. RibP_bind_barrel. 1 hit.
ProtoNet	Search...

Entry information

Entry name

TRPF_THEYD

Accession

Primary (citable) accession number: B5YKL4

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	November 25, 2008
Last modified:	May 1, 2013
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program