Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

B5YJY3 (MUTS_THEYD) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
DNA mismatch repair protein MutS
Gene names
Name:mutS
Ordered Locus Names:THEYE_A0706
OrganismThermodesulfovibrio yellowstonii (strain ATCC 51303 / DSM 11347 / YP87) [Reference proteome] [HAMAP]
Taxonomic identifier289376 [NCBI]
Taxonomic lineageBacteriaNitrospiraeNitrospiralesNitrospiraceaeThermodesulfovibrio

Protein attributes

Sequence length852 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity By similarity. HAMAP-Rule MF_00096

Sequence similarities

Belongs to the DNA mismatch repair MutS family.

Ontologies

Keywords
   Biological processDNA damage
DNA repair
   LigandATP-binding
DNA-binding
Nucleotide-binding
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processmismatch repair

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

damaged DNA binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

mismatched DNA binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 852852DNA mismatch repair protein MutS HAMAP-Rule MF_00096
PRO_1000093652

Regions

Nucleotide binding615 – 6228ATP Potential

Sequences

Sequence LengthMass (Da)Tools
B5YJY3 [UniParc].

Last modified November 25, 2008. Version 1.
Checksum: D3368DA92FB2B990

FASTA85297,306
        10         20         30         40         50         60 
MEVSQEELTP LMRQYLRVKE QYKDAIVFFR LGDFYEMFGE DAVIASKILG ITLTSRDKSK 

        70         80         90        100        110        120 
EKAIPMCGIP YFSADSYIEK LLREGYKVAI CEQIGDPKTS KGIVEREVIK VLTPGTYLPE 

       130        140        150        160        170        180 
GVRENIYIMS IYPSKGKIGI ALADITTGQF FLYETDKNIT DEIERFEPKE ILIPASFEDS 

       190        200        210        220        230        240 
LKFEISSYNK TFIEDWKFDY LLAYKTLLEH FKVASLKSYG AEEFSNAISA GGALLKYLEE 

       250        260        270        280        290        300 
NKQQTEFKGI KILNLSEFML LDASTKKNLE IFVSLDGSRE GSLIWVLDET LTPMGARFLK 

       310        320        330        340        350        360 
NTLSCPLLNI SEIEKRFDGI EAFCGDYLLR EKLEKILKDF PDIERIALKI KGKSINPKEL 

       370        380        390        400        410        420 
NSLKNALKRI PELREVLRNK TEILNSLYNS LYELNELVTK IENALTENPP PVITEGGIFR 

       430        440        450        460        470        480 
DGYNSTIDEL RALRTESKKY ILNMEAEERK KTGINSLKIG YNRVFGYYIE VTKPNLHLVP 

       490        500        510        520        530        540 
SHYIRKQTLA NAERFITEEL KELELKIMSA EEKLKILEQE LFIELVNSIL PFTDKILNNG 

       550        560        570        580        590        600 
ETIGFIDFLL SLAKVASKYN YVRPEINEED IIEIKDGRHP VIERLIQLGK LYEGRFIPND 

       610        620        630        640        650        660 
LLIGPADQRI IILTGPNMAG KSTYMRQNAL IVLMAQIGSF VPAKYAKIGI VDRIFTRIGA 

       670        680        690        700        710        720 
SDYLAKGQST FMVEMIETAN ILNNATPKSF IILDEVGRGT STFDGISIAW SVVEYIAEKI 

       730        740        750        760        770        780 
KARTLFATHY HELTDLAFNL DCIKNFTVVV KEWGDEIIFL RKIQEGGADK SYGIQVARLA 

       790        800        810        820        830        840 
GLPLEILNRA REILHRLEKK EFQVFPIRAR QLDLFFQGDP IKAELSKIDI DSLNPQKALK 

       850 
KLKELKEMLK ND 

« Hide

References

[1]"The complete genome sequence of Thermodesulfovibrio yellowstonii strain ATCC 51303 / DSM 11347 / YP87."
Dodson R.J., Durkin A.S., Wu M., Eisen J., Sutton G.
Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 51303 / DSM 11347 / YP87.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001147 Genomic DNA. Translation: ACI20467.1.
RefSeqYP_002248548.1. NC_011296.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING289376.THEYE_A0706.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACI20467; ACI20467; THEYE_A0706.
GeneID6942606.
KEGGtye:THEYE_A0706.
PATRIC23908433. VBITheYel104483_0698.

Phylogenomic databases

eggNOGCOG0249.
HOGENOMHOG000221406.
KOK03555.
OMAMMAQYLE.
OrthoDBEOG6Q5NPV.

Enzyme and pathway databases

BioCycTYEL289376:GH9L-704-MONOMER.

Family and domain databases

Gene3D3.30.420.110. 1 hit.
3.40.1170.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPMF_00096. MutS.
InterProIPR005748. DNA_mismatch_repair_MutS-1.
IPR007695. DNA_mismatch_repair_MutS-lik_N.
IPR000432. DNA_mismatch_repair_MutS_C.
IPR007861. DNA_mismatch_repair_MutS_clamp.
IPR007696. DNA_mismatch_repair_MutS_core.
IPR016151. DNA_mismatch_repair_MutS_N.
IPR007860. DNA_mmatch_repair_MutS_con_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERPTHR11361:SF34. PTHR11361:SF34. 1 hit.
PfamPF01624. MutS_I. 1 hit.
PF05188. MutS_II. 1 hit.
PF05192. MutS_III. 1 hit.
PF05190. MutS_IV. 1 hit.
PF00488. MutS_V. 1 hit.
[Graphical view]
SMARTSM00534. MUTSac. 1 hit.
SM00533. MUTSd. 1 hit.
[Graphical view]
SUPFAMSSF48334. SSF48334. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF53150. SSF53150. 1 hit.
SSF55271. SSF55271. 1 hit.
TIGRFAMsTIGR01070. mutS1. 1 hit.
PROSITEPS00486. DNA_MISMATCH_REPAIR_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMUTS_THEYD
AccessionPrimary (citable) accession number: B5YJY3
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: November 25, 2008
Last modified: April 16, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families