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B5YJY3

- MUTS_THEYD

UniProt

B5YJY3 - MUTS_THEYD

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Protein

DNA mismatch repair protein MutS

Gene
mutS, THEYE_A0706
Organism
Thermodesulfovibrio yellowstonii (strain ATCC 51303 / DSM 11347 / YP87)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity By similarity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi615 – 6228ATP Reviewed prediction

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. damaged DNA binding Source: UniProtKB-HAMAP
  3. mismatched DNA binding Source: InterPro

GO - Biological processi

  1. mismatch repair Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Biological processi

DNA damage, DNA repair

Keywords - Ligandi

ATP-binding, DNA-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciTYEL289376:GH9L-704-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA mismatch repair protein MutS
Gene namesi
Name:mutS
Ordered Locus Names:THEYE_A0706
OrganismiThermodesulfovibrio yellowstonii (strain ATCC 51303 / DSM 11347 / YP87)
Taxonomic identifieri289376 [NCBI]
Taxonomic lineageiBacteriaNitrospiraeNitrospiralesNitrospiraceaeThermodesulfovibrio
ProteomesiUP000000718: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 852852DNA mismatch repair protein MutSUniRule annotationPRO_1000093652Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi289376.THEYE_A0706.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0249.
HOGENOMiHOG000221406.
KOiK03555.
OMAiILECARH.
OrthoDBiEOG6Q5NPV.

Family and domain databases

Gene3Di3.30.420.110. 1 hit.
3.40.1170.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00096. MutS.
InterProiIPR005748. DNA_mismatch_repair_MutS-1.
IPR007695. DNA_mismatch_repair_MutS-lik_N.
IPR000432. DNA_mismatch_repair_MutS_C.
IPR007861. DNA_mismatch_repair_MutS_clamp.
IPR007696. DNA_mismatch_repair_MutS_core.
IPR016151. DNA_mismatch_repair_MutS_N.
IPR007860. DNA_mmatch_repair_MutS_con_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF01624. MutS_I. 1 hit.
PF05188. MutS_II. 1 hit.
PF05192. MutS_III. 1 hit.
PF05190. MutS_IV. 1 hit.
PF00488. MutS_V. 1 hit.
[Graphical view]
SMARTiSM00534. MUTSac. 1 hit.
SM00533. MUTSd. 1 hit.
[Graphical view]
SUPFAMiSSF48334. SSF48334. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF53150. SSF53150. 1 hit.
SSF55271. SSF55271. 1 hit.
TIGRFAMsiTIGR01070. mutS1. 1 hit.
PROSITEiPS00486. DNA_MISMATCH_REPAIR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B5YJY3-1 [UniParc]FASTAAdd to Basket

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MEVSQEELTP LMRQYLRVKE QYKDAIVFFR LGDFYEMFGE DAVIASKILG    50
ITLTSRDKSK EKAIPMCGIP YFSADSYIEK LLREGYKVAI CEQIGDPKTS 100
KGIVEREVIK VLTPGTYLPE GVRENIYIMS IYPSKGKIGI ALADITTGQF 150
FLYETDKNIT DEIERFEPKE ILIPASFEDS LKFEISSYNK TFIEDWKFDY 200
LLAYKTLLEH FKVASLKSYG AEEFSNAISA GGALLKYLEE NKQQTEFKGI 250
KILNLSEFML LDASTKKNLE IFVSLDGSRE GSLIWVLDET LTPMGARFLK 300
NTLSCPLLNI SEIEKRFDGI EAFCGDYLLR EKLEKILKDF PDIERIALKI 350
KGKSINPKEL NSLKNALKRI PELREVLRNK TEILNSLYNS LYELNELVTK 400
IENALTENPP PVITEGGIFR DGYNSTIDEL RALRTESKKY ILNMEAEERK 450
KTGINSLKIG YNRVFGYYIE VTKPNLHLVP SHYIRKQTLA NAERFITEEL 500
KELELKIMSA EEKLKILEQE LFIELVNSIL PFTDKILNNG ETIGFIDFLL 550
SLAKVASKYN YVRPEINEED IIEIKDGRHP VIERLIQLGK LYEGRFIPND 600
LLIGPADQRI IILTGPNMAG KSTYMRQNAL IVLMAQIGSF VPAKYAKIGI 650
VDRIFTRIGA SDYLAKGQST FMVEMIETAN ILNNATPKSF IILDEVGRGT 700
STFDGISIAW SVVEYIAEKI KARTLFATHY HELTDLAFNL DCIKNFTVVV 750
KEWGDEIIFL RKIQEGGADK SYGIQVARLA GLPLEILNRA REILHRLEKK 800
EFQVFPIRAR QLDLFFQGDP IKAELSKIDI DSLNPQKALK KLKELKEMLK 850
ND 852
Length:852
Mass (Da):97,306
Last modified:November 25, 2008 - v1
Checksum:iD3368DA92FB2B990
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001147 Genomic DNA. Translation: ACI20467.1.
RefSeqiYP_002248548.1. NC_011296.1.

Genome annotation databases

EnsemblBacteriaiACI20467; ACI20467; THEYE_A0706.
GeneIDi6942606.
KEGGitye:THEYE_A0706.
PATRICi23908433. VBITheYel104483_0698.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001147 Genomic DNA. Translation: ACI20467.1 .
RefSeqi YP_002248548.1. NC_011296.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 289376.THEYE_A0706.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACI20467 ; ACI20467 ; THEYE_A0706 .
GeneIDi 6942606.
KEGGi tye:THEYE_A0706.
PATRICi 23908433. VBITheYel104483_0698.

Phylogenomic databases

eggNOGi COG0249.
HOGENOMi HOG000221406.
KOi K03555.
OMAi ILECARH.
OrthoDBi EOG6Q5NPV.

Enzyme and pathway databases

BioCyci TYEL289376:GH9L-704-MONOMER.

Family and domain databases

Gene3Di 3.30.420.110. 1 hit.
3.40.1170.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPi MF_00096. MutS.
InterProi IPR005748. DNA_mismatch_repair_MutS-1.
IPR007695. DNA_mismatch_repair_MutS-lik_N.
IPR000432. DNA_mismatch_repair_MutS_C.
IPR007861. DNA_mismatch_repair_MutS_clamp.
IPR007696. DNA_mismatch_repair_MutS_core.
IPR016151. DNA_mismatch_repair_MutS_N.
IPR007860. DNA_mmatch_repair_MutS_con_dom.
IPR027417. P-loop_NTPase.
[Graphical view ]
Pfami PF01624. MutS_I. 1 hit.
PF05188. MutS_II. 1 hit.
PF05192. MutS_III. 1 hit.
PF05190. MutS_IV. 1 hit.
PF00488. MutS_V. 1 hit.
[Graphical view ]
SMARTi SM00534. MUTSac. 1 hit.
SM00533. MUTSd. 1 hit.
[Graphical view ]
SUPFAMi SSF48334. SSF48334. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF53150. SSF53150. 1 hit.
SSF55271. SSF55271. 1 hit.
TIGRFAMsi TIGR01070. mutS1. 1 hit.
PROSITEi PS00486. DNA_MISMATCH_REPAIR_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The complete genome sequence of Thermodesulfovibrio yellowstonii strain ATCC 51303 / DSM 11347 / YP87."
    Dodson R.J., Durkin A.S., Wu M., Eisen J., Sutton G.
    Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51303 / DSM 11347 / YP87.

Entry informationi

Entry nameiMUTS_THEYD
AccessioniPrimary (citable) accession number: B5YJY3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: November 25, 2008
Last modified: June 11, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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