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Protein

DNA mismatch repair protein MutS

Gene

mutS

Organism
Thermodesulfovibrio yellowstonii (strain ATCC 51303 / DSM 11347 / YP87)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi615 – 622ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processDNA damage, DNA repair
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciTYEL289376:G1GCQ-705-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
DNA mismatch repair protein MutSUniRule annotation
Gene namesi
Name:mutSUniRule annotation
Ordered Locus Names:THEYE_A0706
OrganismiThermodesulfovibrio yellowstonii (strain ATCC 51303 / DSM 11347 / YP87)
Taxonomic identifieri289376 [NCBI]
Taxonomic lineageiBacteriaNitrospiraeNitrospiralesNitrospiraceaeThermodesulfovibrio
Proteomesi
  • UP000000718 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000936521 – 852DNA mismatch repair protein MutSAdd BLAST852

Proteomic databases

PRIDEiB5YJY3

Interactioni

Protein-protein interaction databases

STRINGi289376.THEYE_A0706

Structurei

3D structure databases

SMRiB5YJY3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the DNA mismatch repair MutS family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D86 Bacteria
COG0249 LUCA
HOGENOMiHOG000221406
InParanoidiB5YJY3
KOiK03555
OMAiTPMMAQY
OrthoDBiPOG091H0293

Family and domain databases

Gene3Di3.30.420.110, 1 hit
3.40.1170.10, 1 hit
HAMAPiMF_00096 MutS, 1 hit
InterProiView protein in InterPro
IPR005748 DNA_mismatch_repair_MutS
IPR007695 DNA_mismatch_repair_MutS-lik_N
IPR017261 DNA_mismatch_repair_MutS/MSH
IPR000432 DNA_mismatch_repair_MutS_C
IPR007861 DNA_mismatch_repair_MutS_clamp
IPR007696 DNA_mismatch_repair_MutS_core
IPR016151 DNA_mismatch_repair_MutS_N
IPR036187 DNA_mismatch_repair_MutS_sf
IPR007860 DNA_mmatch_repair_MutS_con_dom
IPR036678 MutS_con_dom_sf
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF01624 MutS_I, 1 hit
PF05188 MutS_II, 1 hit
PF05192 MutS_III, 1 hit
PF05190 MutS_IV, 1 hit
PF00488 MutS_V, 1 hit
PIRSFiPIRSF037677 DNA_mis_repair_Msh6, 1 hit
SMARTiView protein in SMART
SM00534 MUTSac, 1 hit
SM00533 MUTSd, 1 hit
SUPFAMiSSF48334 SSF48334, 1 hit
SSF52540 SSF52540, 1 hit
SSF53150 SSF53150, 1 hit
SSF55271 SSF55271, 1 hit
TIGRFAMsiTIGR01070 mutS1, 1 hit
PROSITEiView protein in PROSITE
PS00486 DNA_MISMATCH_REPAIR_2, 1 hit

Sequencei

Sequence statusi: Complete.

B5YJY3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEVSQEELTP LMRQYLRVKE QYKDAIVFFR LGDFYEMFGE DAVIASKILG
60 70 80 90 100
ITLTSRDKSK EKAIPMCGIP YFSADSYIEK LLREGYKVAI CEQIGDPKTS
110 120 130 140 150
KGIVEREVIK VLTPGTYLPE GVRENIYIMS IYPSKGKIGI ALADITTGQF
160 170 180 190 200
FLYETDKNIT DEIERFEPKE ILIPASFEDS LKFEISSYNK TFIEDWKFDY
210 220 230 240 250
LLAYKTLLEH FKVASLKSYG AEEFSNAISA GGALLKYLEE NKQQTEFKGI
260 270 280 290 300
KILNLSEFML LDASTKKNLE IFVSLDGSRE GSLIWVLDET LTPMGARFLK
310 320 330 340 350
NTLSCPLLNI SEIEKRFDGI EAFCGDYLLR EKLEKILKDF PDIERIALKI
360 370 380 390 400
KGKSINPKEL NSLKNALKRI PELREVLRNK TEILNSLYNS LYELNELVTK
410 420 430 440 450
IENALTENPP PVITEGGIFR DGYNSTIDEL RALRTESKKY ILNMEAEERK
460 470 480 490 500
KTGINSLKIG YNRVFGYYIE VTKPNLHLVP SHYIRKQTLA NAERFITEEL
510 520 530 540 550
KELELKIMSA EEKLKILEQE LFIELVNSIL PFTDKILNNG ETIGFIDFLL
560 570 580 590 600
SLAKVASKYN YVRPEINEED IIEIKDGRHP VIERLIQLGK LYEGRFIPND
610 620 630 640 650
LLIGPADQRI IILTGPNMAG KSTYMRQNAL IVLMAQIGSF VPAKYAKIGI
660 670 680 690 700
VDRIFTRIGA SDYLAKGQST FMVEMIETAN ILNNATPKSF IILDEVGRGT
710 720 730 740 750
STFDGISIAW SVVEYIAEKI KARTLFATHY HELTDLAFNL DCIKNFTVVV
760 770 780 790 800
KEWGDEIIFL RKIQEGGADK SYGIQVARLA GLPLEILNRA REILHRLEKK
810 820 830 840 850
EFQVFPIRAR QLDLFFQGDP IKAELSKIDI DSLNPQKALK KLKELKEMLK

ND
Length:852
Mass (Da):97,306
Last modified:November 25, 2008 - v1
Checksum:iD3368DA92FB2B990
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001147 Genomic DNA Translation: ACI20467.1
RefSeqiWP_012545203.1, NC_011296.1
YP_002248548.1, NC_011296.1

Genome annotation databases

EnsemblBacteriaiACI20467; ACI20467; THEYE_A0706
GeneIDi6942606
KEGGitye:THEYE_A0706
PATRICifig|289376.4.peg.698

Similar proteinsi

Entry informationi

Entry nameiMUTS_THEYD
AccessioniPrimary (citable) accession number: B5YJY3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: November 25, 2008
Last modified: May 23, 2018
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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