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B5YJY3

- MUTS_THEYD

UniProt

B5YJY3 - MUTS_THEYD

Protein

DNA mismatch repair protein MutS

Gene

mutS

Organism
Thermodesulfovibrio yellowstonii (strain ATCC 51303 / DSM 11347 / YP87)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 41 (01 Oct 2014)
      Sequence version 1 (25 Nov 2008)
      Previous versions | rss
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    Functioni

    This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi615 – 6228ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. damaged DNA binding Source: UniProtKB-HAMAP
    3. mismatched DNA binding Source: InterPro

    GO - Biological processi

    1. mismatch repair Source: UniProtKB-HAMAP

    Keywords - Biological processi

    DNA damage, DNA repair

    Keywords - Ligandi

    ATP-binding, DNA-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciTYEL289376:GH9L-704-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA mismatch repair protein MutSUniRule annotation
    Gene namesi
    Name:mutSUniRule annotation
    Ordered Locus Names:THEYE_A0706
    OrganismiThermodesulfovibrio yellowstonii (strain ATCC 51303 / DSM 11347 / YP87)
    Taxonomic identifieri289376 [NCBI]
    Taxonomic lineageiBacteriaNitrospiraeNitrospiralesNitrospiraceaeThermodesulfovibrio
    ProteomesiUP000000718: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 852852DNA mismatch repair protein MutSPRO_1000093652Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi289376.THEYE_A0706.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the DNA mismatch repair MutS family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0249.
    HOGENOMiHOG000221406.
    KOiK03555.
    OMAiILECARH.
    OrthoDBiEOG6Q5NPV.

    Family and domain databases

    Gene3Di3.30.420.110. 1 hit.
    3.40.1170.10. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPiMF_00096. MutS.
    InterProiIPR005748. DNA_mismatch_repair_MutS-1.
    IPR007695. DNA_mismatch_repair_MutS-lik_N.
    IPR000432. DNA_mismatch_repair_MutS_C.
    IPR007861. DNA_mismatch_repair_MutS_clamp.
    IPR007696. DNA_mismatch_repair_MutS_core.
    IPR016151. DNA_mismatch_repair_MutS_N.
    IPR007860. DNA_mmatch_repair_MutS_con_dom.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PfamiPF01624. MutS_I. 1 hit.
    PF05188. MutS_II. 1 hit.
    PF05192. MutS_III. 1 hit.
    PF05190. MutS_IV. 1 hit.
    PF00488. MutS_V. 1 hit.
    [Graphical view]
    SMARTiSM00534. MUTSac. 1 hit.
    SM00533. MUTSd. 1 hit.
    [Graphical view]
    SUPFAMiSSF48334. SSF48334. 1 hit.
    SSF52540. SSF52540. 1 hit.
    SSF53150. SSF53150. 1 hit.
    SSF55271. SSF55271. 1 hit.
    TIGRFAMsiTIGR01070. mutS1. 1 hit.
    PROSITEiPS00486. DNA_MISMATCH_REPAIR_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B5YJY3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEVSQEELTP LMRQYLRVKE QYKDAIVFFR LGDFYEMFGE DAVIASKILG    50
    ITLTSRDKSK EKAIPMCGIP YFSADSYIEK LLREGYKVAI CEQIGDPKTS 100
    KGIVEREVIK VLTPGTYLPE GVRENIYIMS IYPSKGKIGI ALADITTGQF 150
    FLYETDKNIT DEIERFEPKE ILIPASFEDS LKFEISSYNK TFIEDWKFDY 200
    LLAYKTLLEH FKVASLKSYG AEEFSNAISA GGALLKYLEE NKQQTEFKGI 250
    KILNLSEFML LDASTKKNLE IFVSLDGSRE GSLIWVLDET LTPMGARFLK 300
    NTLSCPLLNI SEIEKRFDGI EAFCGDYLLR EKLEKILKDF PDIERIALKI 350
    KGKSINPKEL NSLKNALKRI PELREVLRNK TEILNSLYNS LYELNELVTK 400
    IENALTENPP PVITEGGIFR DGYNSTIDEL RALRTESKKY ILNMEAEERK 450
    KTGINSLKIG YNRVFGYYIE VTKPNLHLVP SHYIRKQTLA NAERFITEEL 500
    KELELKIMSA EEKLKILEQE LFIELVNSIL PFTDKILNNG ETIGFIDFLL 550
    SLAKVASKYN YVRPEINEED IIEIKDGRHP VIERLIQLGK LYEGRFIPND 600
    LLIGPADQRI IILTGPNMAG KSTYMRQNAL IVLMAQIGSF VPAKYAKIGI 650
    VDRIFTRIGA SDYLAKGQST FMVEMIETAN ILNNATPKSF IILDEVGRGT 700
    STFDGISIAW SVVEYIAEKI KARTLFATHY HELTDLAFNL DCIKNFTVVV 750
    KEWGDEIIFL RKIQEGGADK SYGIQVARLA GLPLEILNRA REILHRLEKK 800
    EFQVFPIRAR QLDLFFQGDP IKAELSKIDI DSLNPQKALK KLKELKEMLK 850
    ND 852
    Length:852
    Mass (Da):97,306
    Last modified:November 25, 2008 - v1
    Checksum:iD3368DA92FB2B990
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001147 Genomic DNA. Translation: ACI20467.1.
    RefSeqiYP_002248548.1. NC_011296.1.

    Genome annotation databases

    EnsemblBacteriaiACI20467; ACI20467; THEYE_A0706.
    GeneIDi6942606.
    KEGGitye:THEYE_A0706.
    PATRICi23908433. VBITheYel104483_0698.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001147 Genomic DNA. Translation: ACI20467.1 .
    RefSeqi YP_002248548.1. NC_011296.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 289376.THEYE_A0706.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACI20467 ; ACI20467 ; THEYE_A0706 .
    GeneIDi 6942606.
    KEGGi tye:THEYE_A0706.
    PATRICi 23908433. VBITheYel104483_0698.

    Phylogenomic databases

    eggNOGi COG0249.
    HOGENOMi HOG000221406.
    KOi K03555.
    OMAi ILECARH.
    OrthoDBi EOG6Q5NPV.

    Enzyme and pathway databases

    BioCyci TYEL289376:GH9L-704-MONOMER.

    Family and domain databases

    Gene3Di 3.30.420.110. 1 hit.
    3.40.1170.10. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPi MF_00096. MutS.
    InterProi IPR005748. DNA_mismatch_repair_MutS-1.
    IPR007695. DNA_mismatch_repair_MutS-lik_N.
    IPR000432. DNA_mismatch_repair_MutS_C.
    IPR007861. DNA_mismatch_repair_MutS_clamp.
    IPR007696. DNA_mismatch_repair_MutS_core.
    IPR016151. DNA_mismatch_repair_MutS_N.
    IPR007860. DNA_mmatch_repair_MutS_con_dom.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    Pfami PF01624. MutS_I. 1 hit.
    PF05188. MutS_II. 1 hit.
    PF05192. MutS_III. 1 hit.
    PF05190. MutS_IV. 1 hit.
    PF00488. MutS_V. 1 hit.
    [Graphical view ]
    SMARTi SM00534. MUTSac. 1 hit.
    SM00533. MUTSd. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48334. SSF48334. 1 hit.
    SSF52540. SSF52540. 1 hit.
    SSF53150. SSF53150. 1 hit.
    SSF55271. SSF55271. 1 hit.
    TIGRFAMsi TIGR01070. mutS1. 1 hit.
    PROSITEi PS00486. DNA_MISMATCH_REPAIR_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The complete genome sequence of Thermodesulfovibrio yellowstonii strain ATCC 51303 / DSM 11347 / YP87."
      Dodson R.J., Durkin A.S., Wu M., Eisen J., Sutton G.
      Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 51303 / DSM 11347 / YP87.

    Entry informationi

    Entry nameiMUTS_THEYD
    AccessioniPrimary (citable) accession number: B5YJY3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 24, 2009
    Last sequence update: November 25, 2008
    Last modified: October 1, 2014
    This is version 41 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3