Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

DNA mismatch repair protein MutS

Gene

mutS

Organism
Thermodesulfovibrio yellowstonii (strain ATCC 51303 / DSM 11347 / YP87)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi615 – 6228ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. damaged DNA binding Source: UniProtKB-HAMAP
  3. mismatched DNA binding Source: InterPro

GO - Biological processi

  1. mismatch repair Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Biological processi

DNA damage, DNA repair

Keywords - Ligandi

ATP-binding, DNA-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciTYEL289376:GH9L-704-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA mismatch repair protein MutSUniRule annotation
Gene namesi
Name:mutSUniRule annotation
Ordered Locus Names:THEYE_A0706
OrganismiThermodesulfovibrio yellowstonii (strain ATCC 51303 / DSM 11347 / YP87)
Taxonomic identifieri289376 [NCBI]
Taxonomic lineageiBacteriaNitrospiraeNitrospiralesNitrospiraceaeThermodesulfovibrio
ProteomesiUP000000718 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 852852DNA mismatch repair protein MutSPRO_1000093652Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi289376.THEYE_A0706.

Family & Domainsi

Sequence similaritiesi

Belongs to the DNA mismatch repair MutS family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0249.
HOGENOMiHOG000221406.
InParanoidiB5YJY3.
KOiK03555.
OMAiKITSAFT.
OrthoDBiEOG6Q5NPV.

Family and domain databases

Gene3Di3.30.420.110. 1 hit.
3.40.1170.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00096. MutS.
InterProiIPR005748. DNA_mismatch_repair_MutS-1.
IPR007695. DNA_mismatch_repair_MutS-lik_N.
IPR000432. DNA_mismatch_repair_MutS_C.
IPR007861. DNA_mismatch_repair_MutS_clamp.
IPR007696. DNA_mismatch_repair_MutS_core.
IPR016151. DNA_mismatch_repair_MutS_N.
IPR007860. DNA_mmatch_repair_MutS_con_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF01624. MutS_I. 1 hit.
PF05188. MutS_II. 1 hit.
PF05192. MutS_III. 1 hit.
PF05190. MutS_IV. 1 hit.
PF00488. MutS_V. 1 hit.
[Graphical view]
SMARTiSM00534. MUTSac. 1 hit.
SM00533. MUTSd. 1 hit.
[Graphical view]
SUPFAMiSSF48334. SSF48334. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF53150. SSF53150. 1 hit.
SSF55271. SSF55271. 1 hit.
TIGRFAMsiTIGR01070. mutS1. 1 hit.
PROSITEiPS00486. DNA_MISMATCH_REPAIR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B5YJY3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEVSQEELTP LMRQYLRVKE QYKDAIVFFR LGDFYEMFGE DAVIASKILG
60 70 80 90 100
ITLTSRDKSK EKAIPMCGIP YFSADSYIEK LLREGYKVAI CEQIGDPKTS
110 120 130 140 150
KGIVEREVIK VLTPGTYLPE GVRENIYIMS IYPSKGKIGI ALADITTGQF
160 170 180 190 200
FLYETDKNIT DEIERFEPKE ILIPASFEDS LKFEISSYNK TFIEDWKFDY
210 220 230 240 250
LLAYKTLLEH FKVASLKSYG AEEFSNAISA GGALLKYLEE NKQQTEFKGI
260 270 280 290 300
KILNLSEFML LDASTKKNLE IFVSLDGSRE GSLIWVLDET LTPMGARFLK
310 320 330 340 350
NTLSCPLLNI SEIEKRFDGI EAFCGDYLLR EKLEKILKDF PDIERIALKI
360 370 380 390 400
KGKSINPKEL NSLKNALKRI PELREVLRNK TEILNSLYNS LYELNELVTK
410 420 430 440 450
IENALTENPP PVITEGGIFR DGYNSTIDEL RALRTESKKY ILNMEAEERK
460 470 480 490 500
KTGINSLKIG YNRVFGYYIE VTKPNLHLVP SHYIRKQTLA NAERFITEEL
510 520 530 540 550
KELELKIMSA EEKLKILEQE LFIELVNSIL PFTDKILNNG ETIGFIDFLL
560 570 580 590 600
SLAKVASKYN YVRPEINEED IIEIKDGRHP VIERLIQLGK LYEGRFIPND
610 620 630 640 650
LLIGPADQRI IILTGPNMAG KSTYMRQNAL IVLMAQIGSF VPAKYAKIGI
660 670 680 690 700
VDRIFTRIGA SDYLAKGQST FMVEMIETAN ILNNATPKSF IILDEVGRGT
710 720 730 740 750
STFDGISIAW SVVEYIAEKI KARTLFATHY HELTDLAFNL DCIKNFTVVV
760 770 780 790 800
KEWGDEIIFL RKIQEGGADK SYGIQVARLA GLPLEILNRA REILHRLEKK
810 820 830 840 850
EFQVFPIRAR QLDLFFQGDP IKAELSKIDI DSLNPQKALK KLKELKEMLK

ND
Length:852
Mass (Da):97,306
Last modified:November 25, 2008 - v1
Checksum:iD3368DA92FB2B990
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001147 Genomic DNA. Translation: ACI20467.1.
RefSeqiWP_012545203.1. NC_011296.1.
YP_002248548.1. NC_011296.1.

Genome annotation databases

EnsemblBacteriaiACI20467; ACI20467; THEYE_A0706.
GeneIDi6942606.
KEGGitye:THEYE_A0706.
PATRICi23908433. VBITheYel104483_0698.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001147 Genomic DNA. Translation: ACI20467.1.
RefSeqiWP_012545203.1. NC_011296.1.
YP_002248548.1. NC_011296.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi289376.THEYE_A0706.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACI20467; ACI20467; THEYE_A0706.
GeneIDi6942606.
KEGGitye:THEYE_A0706.
PATRICi23908433. VBITheYel104483_0698.

Phylogenomic databases

eggNOGiCOG0249.
HOGENOMiHOG000221406.
InParanoidiB5YJY3.
KOiK03555.
OMAiKITSAFT.
OrthoDBiEOG6Q5NPV.

Enzyme and pathway databases

BioCyciTYEL289376:GH9L-704-MONOMER.

Family and domain databases

Gene3Di3.30.420.110. 1 hit.
3.40.1170.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00096. MutS.
InterProiIPR005748. DNA_mismatch_repair_MutS-1.
IPR007695. DNA_mismatch_repair_MutS-lik_N.
IPR000432. DNA_mismatch_repair_MutS_C.
IPR007861. DNA_mismatch_repair_MutS_clamp.
IPR007696. DNA_mismatch_repair_MutS_core.
IPR016151. DNA_mismatch_repair_MutS_N.
IPR007860. DNA_mmatch_repair_MutS_con_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF01624. MutS_I. 1 hit.
PF05188. MutS_II. 1 hit.
PF05192. MutS_III. 1 hit.
PF05190. MutS_IV. 1 hit.
PF00488. MutS_V. 1 hit.
[Graphical view]
SMARTiSM00534. MUTSac. 1 hit.
SM00533. MUTSd. 1 hit.
[Graphical view]
SUPFAMiSSF48334. SSF48334. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF53150. SSF53150. 1 hit.
SSF55271. SSF55271. 1 hit.
TIGRFAMsiTIGR01070. mutS1. 1 hit.
PROSITEiPS00486. DNA_MISMATCH_REPAIR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The complete genome sequence of Thermodesulfovibrio yellowstonii strain ATCC 51303 / DSM 11347 / YP87."
    Dodson R.J., Durkin A.S., Wu M., Eisen J., Sutton G.
    Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51303 / DSM 11347 / YP87.

Entry informationi

Entry nameiMUTS_THEYD
AccessioniPrimary (citable) accession number: B5YJY3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: November 25, 2008
Last modified: April 1, 2015
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.