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B5YFH5 (B5YFH5_DICT6) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Dihydroorotase RuleBase RU003441
EC=3.5.2.3 RuleBase RU003441
Gene names
Ordered Locus Names:DICTH_1464
OrganismDictyoglomus thermophilum (strain ATCC 35947 / DSM 3960 / H-6-12) [Complete proteome] [HAMAP]
Taxonomic identifier309799 [NCBI]
Taxonomic lineageBacteria › Dictyoglomi › Dictyoglomales › Dictyoglomaceae › Dictyoglomus

Protein attributes

Sequence length432 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(S)-dihydroorotate + H2O = N-carbamoyl-L-aspartate. RuleBase RU003441 SAAS SAAS002195

Cofactor

Binds 2 zinc ions per subunit By similarity. RuleBase RU003441 SAAS SAAS002195

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 3/3. RuleBase RU003441 SAAS SAAS002195

Subunit structure

Homodimer By similarity. SAAS SAAS002195

Sequence similarities

Belongs to the DHOase family. Type 2 subfamily. RuleBase RU003441

Sequences

Sequence LengthMass (Da)Tools
B5YFH5 [UniParc].

Last modified November 25, 2008. Version 1.
Checksum: 8BD9564FBDCDFF0D

FASTA43248,769
        10         20         30         40         50         60 
MKILFKNVTL IYPEKDMEET GDLYVENGVI KKIGKNLDIN GDVEIIEGQN KVLAPTLVDM 

        70         80         90        100        110        120 
HVHLREPGYE WKEDIESGCK AAVAGGFTAV CCMPNTNPPI DNKEIVRFIY EKSDIIGLSR 

       130        140        150        160        170        180 
VYPIGTITKG REGKEISEMG DMYMAGAKAF SDDGNCVMNS EVLRYALEYS KIFDVPIIEH 

       190        200        210        220        230        240 
AEDINLTLDG NVNFGKISTL LGFKGMPWVA EASIVARDVF LSALTGGKLH VAHISCWQSL 

       250        260        270        280        290        300 
DMIRWGKEHG VNVTCEVTPH HLVLTEDAVK ELDYDPNTKM NPPLRTKEDQ EALWEGIKND 

       310        320        330        340        350        360 
LIDVIATDHA PHHLDDKMVE YGLAEYGISG LETAIPLILT YGYYERKIPL HKIFKKMSYN 

       370        380        390        400        410        420 
PCKILNLPYI PLEENVPANF TVIDLSLEKE VDKEKFFSKG KNTPFHGWKL KGWPIMTFVE 

       430 
GRLVYREGKI LW

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References

[1]"The complete genome sequence of Dictyoglomus thermophilum strain ATCC 35947 / DSM 3960 / H-6-12."
Dodson R.J., Durkin A.S., Wu M., Eisen J., Sutton G.
Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001146 Genomic DNA. Translation: ACI19622.1.
RefSeqYP_002251283.1. NC_011297.1.

3D structure databases

ProteinModelPortalB5YFH5.
ModBaseSearch...

Protein-protein interaction databases

STRINGB5YFH5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6944902.
GenomeReviewsGene locus DICTH_1464 in contig CP001146_GR.
KEGGdth:DICTH_1464.
PATRIC21807552. VBIDicThe33784_1407.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG724623.
OMACDVHPVG.
ProtClustDBCLSK2409859.

Family and domain databases

HAMAPMF_00220_B. PyrC_type2_B.
[Tree]
InterProIPR006680. Amidohydro_1.
IPR004722. DHOase.
IPR002195. Dihydroorotase_CS.
IPR011059. Metal-dep_hydrolase_composite.
[Graphical view]
KOK01465.
PfamPF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMSSF51338. Metalo_hydrolase. 1 hit.
TIGRFAMsTIGR00857. PyrC_multi. 1 hit.
PROSITEPS00482. DIHYDROOROTASE_1. 1 hit.
PS00483. DIHYDROOROTASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB5YFH5_DICT6
AccessionPrimary (citable) accession number: B5YFH5
Entry history
Integrated into UniProtKB/TrEMBL: November 25, 2008
Last sequence update: November 25, 2008
Last modified: December 14, 2011
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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