Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Ribonuclease PH

Gene

rph

Organism
Dictyoglomus thermophilum (strain ATCC 35947 / DSM 3960 / H-6-12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates.

Catalytic activityi

tRNA(n+1) + phosphate = tRNA(n) + a nucleoside diphosphate.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferase, Transferase
Biological processtRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease PH (EC:2.7.7.56)
Short name:
RNase PH
Alternative name(s):
tRNA nucleotidyltransferase
Gene namesi
Name:rph
Ordered Locus Names:DICTH_1223
OrganismiDictyoglomus thermophilum (strain ATCC 35947 / DSM 3960 / H-6-12)
Taxonomic identifieri309799 [NCBI]
Taxonomic lineageiBacteriaDictyoglomiDictyoglomalesDictyoglomaceaeDictyoglomus
Proteomesi
  • UP000001733 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001293371 – 240Ribonuclease PHAdd BLAST240

Interactioni

Protein-protein interaction databases

STRINGi309799.DICTH_1223.

Structurei

3D structure databases

SMRiB5YEU4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RNase PH family.

Phylogenomic databases

eggNOGiENOG4105ED0. Bacteria.
COG0689. LUCA.
HOGENOMiHOG000229516.
KOiK00989.
OMAiKGKGQGW.
OrthoDBiPOG091H03ML.

Family and domain databases

CDDicd11362. RNase_PH_bact. 1 hit.
Gene3Di3.30.230.70. 1 hit.
HAMAPiMF_00564. RNase_PH. 1 hit.
InterProiView protein in InterPro
IPR001247. ExoRNase_PH_dom1.
IPR015847. ExoRNase_PH_dom2.
IPR036345. ExoRNase_PH_dom2_sf.
IPR027408. PNPase/RNase_PH_dom_sf.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR002381. RNase_PH_bac-type.
PfamiView protein in Pfam
PF01138. RNase_PH. 1 hit.
PF03725. RNase_PH_C. 1 hit.
SUPFAMiSSF54211. SSF54211. 1 hit.
SSF55666. SSF55666. 1 hit.
TIGRFAMsiTIGR01966. RNasePH. 1 hit.

Sequencei

Sequence statusi: Complete.

B5YEU4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIRIDKRSNV DLRPVKITRK YLKYPLGSVL IEMGETKVIC TVSMEEKVPP
60 70 80 90 100
FLKGTNQGWL TAEYGMLPGS TPERKVRDVV KGVINGRSQE IQRLIGRSLR
110 120 130 140 150
AVIDFSKLGE RTIWIDTDVI QADGGTRTAA ITGAFVALYD ALEKLKRDGV
160 170 180 190 200
IKEIPIKEFV AAVSVGIVDG EILLDLSANE DMRAEVDMNV VMTESGKFVE
210 220 230 240
IQGTAEKTPF TYEQLQQMLN LAKQGIMKLI EIQKKALGLL
Length:240
Mass (Da):26,683
Last modified:November 25, 2008 - v1
Checksum:i4C8F1B9A866C63B2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001146 Genomic DNA. Translation: ACI19075.1.
RefSeqiWP_012547707.1. NC_011297.1.

Genome annotation databases

EnsemblBacteriaiACI19075; ACI19075; DICTH_1223.
KEGGidth:DICTH_1223.

Similar proteinsi

Entry informationi

Entry nameiRNPH_DICT6
AccessioniPrimary (citable) accession number: B5YEU4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: November 25, 2008
Last modified: November 22, 2017
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families