Reviewed, UniProtKB/Swiss-Prot B5YES5 (SYGA_DICT6)

Names and origin

Protein names

Recommended name:
    Glycyl-tRNA synthetase alpha subunit
    EC=6.1.1.14
Alternative name(s):
    Glycine--tRNA ligase alpha subunit
      Short name=GlyRS

Gene names

Name:	glyQ
Ordered Locus Names:	DICTH_1204

Organism

Dictyoglomus thermophilum (strain ATCC 35947 / DSM 3960 / H-6-12) [Complete proteome] [HAMAP]

Taxonomic identifier

309799 [NCBI]

Taxonomic lineage

Bacteria › Dictyoglomi › Dictyoglomales › Dictyoglomaceae › Dictyoglomus

Protein attributes

Sequence length	299 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP MF_00254
Subunit structure	Tetramer of two alpha and two beta subunits By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP glycine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 299	299	Glycyl-tRNA synthetase alpha subunit HAMAP MF_00254		PRO_1000101185

Sequences

	Sequence		Length	Mass (Da)
	B5YES5-1 [UniParc]. Last modified November 25, 2008. Version 1. Checksum: AF124FB3703A665D	FASTA	299	34,964
	10 20 30 40 50 60 MLFQEIIFKL NEFWHKQGCI IQQPYDIEVG AGTMNPATFF RVLGPEPWYV AYVEPSRRPT 70 80 90 100 110 120 DGRYGENPNR LQHYYQYQVI LKPSPANVQE IYIESLEYLG IDIEKHDIRF VEDNWESPTL 130 140 150 160 170 180 GAWGIGWEVW LDGMEITQFT YFQQCGGFDL FPISAEITYG LERIAMYIQG IDDFKDIKWQ 190 200 210 220 230 240 DGITYGDIHL QSEVENCIYN FELADVERLR LLFNEYEKEA ERLLNEGLTF PGYDYVLKCS 250 260 270 280 290 HTFNLLDARG AISVVQRSQY ISRIRRLAAK AAENYLKSRE ALGFPLLNKA WRKEEAQIG

References

[1]	"The complete genome sequence of Dictyoglomus thermophilum strain ATCC 35947 / DSM 3960 / H-6-12." Dodson R.J., Durkin A.S., Wu M., Eisen J., Sutton G. Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP001146 Genomic DNA. Translation: ACI18824.1.
RefSeq	YP_002251033.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6946023.
GenomeReviews	Gene locus DICTH_1204 in contig CP001146_GR.
KEGG	dth:DICTH_1204.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	CRRPTDG.
Family and domain databases
HAMAP	MF_00254. [Tree]
InterPro	IPR006194. Gly-tRNA-synth_II_heterodimer. IPR002310. Gly-tRNA_synth_IIc_asu. [Graphical view]
Pfam	PF02091. tRNA-synt_2e. 1 hit. [Graphical view]
PRINTS	PR01044. TRNASYNTHGA.
TIGRFAMs	TIGR00388. glyQ. 1 hit.
PROSITE	PS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYGA_DICT6

Accession

Primary (citable) accession number: B5YES5

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	November 25, 2008
Last modified:	November 3, 2009
This is version 9 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)