B5YDY1 (GLMM_DICT6) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	DICTH_0875

Organism

Dictyoglomus thermophilum (strain ATCC 35947 / DSM 3960 / H-6-12) [Complete proteome] [HAMAP]

Taxonomic identifier

309799 [NCBI]

Taxonomic lineage

Bacteria › Dictyoglomi › Dictyoglomales › Dictyoglomaceae › Dictyoglomus

Protein attributes

Sequence length	458 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554_B
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554_B
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554_B
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554_B
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoglucosamine mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 458	458	Phosphoglucosamine mutase HAMAP MF_01554_B		PRO_1000201087
Sites
	Active site	100	1	Phosphoserine intermediate By similarity
	Metal binding	100	1	Magnesium; via phosphate group By similarity
	Metal binding	239	1	Magnesium By similarity
	Metal binding	241	1	Magnesium By similarity
	Metal binding	243	1	Magnesium By similarity
Amino acid modifications
	Modified residue	100	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	B5YDY1 [UniParc]. Last modified November 25, 2008. Version 1. Checksum: 274C644ED156AC68	FASTA	458	51,402
	10 20 30 40 50 60 MRKFFGTDGI RGIVNEILTP ELAYKLSRAI IGYFKDVKKK KVIIGSDTRN SKDMLKSALI 70 80 90 100 110 120 AGFTSGGMDI LDVGVVSTPS LSYLVKKYDD VLLGIMISAS HNPVEYNGIK IFKSDGFKLE 130 140 150 160 170 180 DNVEATIEEY ILREDDYFRA SPREIGVIYN FTQALEDYKN YLKEIIGEDF RGYKIMLDCA 190 200 210 220 230 240 FGSLSEIAPT VFKELGAEVI AYNTNYNGIN INDNCGAVYP EIGRNLFLKS GAHIGFTYDG 250 260 270 280 290 300 DGDRVIAFSE DGEIVDGDVL IGIFAKYLKE RGLLRGNKIV GTVMTNLGLE EYLKRLGIGL 310 320 330 340 350 360 IRAKVGDRYV LEEILKNNLN LGGETSGHII LFDYMPTGDG LLTSLFLLKI LKERGIKLSD 370 380 390 400 410 420 LAKEIRIFPQ VHEKIHIKDI YITEEDEKEF RGIAEEVING KNIRYIVRKS GTEPVIRITV 430 440 450 EGDVPKEDLT NIALEIKNRI IDFLRRSKRQ DLPSKGVS

References

[1]

"The complete genome sequence of Dictyoglomus thermophilum strain ATCC 35947 / DSM 3960 / H-6-12." Dodson R.J., Durkin A.S., Wu M., Eisen J., Sutton G. Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 35947 / DSM 3960 / H-6-12.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001146 Genomic DNA. Translation: ACI18858.1.
RefSeq	YP_002250739.1. NC_011297.1.
3D structure databases
ProteinModelPortal	B5YDY1.
ModBase	Search...
Protein-protein interaction databases
STRING	B5YDY1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6946565.
GenomeReviews	Gene locus DICTH_0875 in contig CP001146_GR.
KEGG	dth:DICTH_0875.
PATRIC	21806388. VBIDicThe33784_0860.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG644964.
OMA	PLEDIQV.
ProtClustDB	CLSK2409410.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_DICT6

Accession

Primary (citable) accession number: B5YDY1

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	November 25, 2008
Last modified:	January 25, 2012
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program