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B5YDE8 (B5YDE8_DICT6) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glycerol kinase HAMAP MF_00186
EC=2.7.1.30 HAMAP MF_00186
Alternative name(s):
ATP:glycerol 3-phosphotransferase HAMAP MF_00186
Glycerokinase HAMAP MF_00186
Gene names
Name:glpK HAMAP MF_00186 EMBL ACI19444.1
Ordered Locus Names:DICTH_0684
OrganismDictyoglomus thermophilum (strain ATCC 35947 / DSM 3960 / H-6-12) [Complete proteome] [HAMAP]
Taxonomic identifier309799 [NCBI]
Taxonomic lineageBacteria › Dictyoglomi › Dictyoglomales › Dictyoglomaceae › Dictyoglomus

Protein attributes

Sequence length494 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Key enzyme in the regulation of glycerol uptake and metabolism By similarity. HAMAP MF_00186 SAAS SAAS018483

Catalytic activity

ATP + glycerol = ADP + sn-glycerol 3-phosphate. HAMAP MF_00186 SAAS SAAS018483

Pathway

Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1. HAMAP MF_00186 SAAS SAAS018483

Sequence similarities

Belongs to the FGGY kinase family. HAMAP MF_00186 RuleBase RU003733

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding406 – 4105ATP By similarity HAMAP MF_00186

Sites

Binding site101Substrate By similarity HAMAP MF_00186
Binding site141ATP By similarity HAMAP MF_00186
Binding site801Substrate By similarity HAMAP MF_00186
Binding site1321Substrate By similarity HAMAP MF_00186
Binding site2401Substrate By similarity HAMAP MF_00186
Binding site2621ATP By similarity HAMAP MF_00186
Binding site3051ATP; via carbonyl oxygen By similarity HAMAP MF_00186

Sequences

Sequence LengthMass (Da)Tools
B5YDE8 [UniParc].

Last modified November 25, 2008. Version 1.
Checksum: FD39C3872C9F90CA

FASTA49455,715
        10         20         30         40         50         60 
MYILALDQGT TSSRAIIFDS LGNIIGVAQK EFPQIFPKPG WVEHNPWDIW NSQREVMFEA 

        70         80         90        100        110        120 
IEKAKIKPKE ISAIGVTNQR ETTIVWDKDT GQPIHNAIVW QCRRTADYCE RLKKDGLSEL 

       130        140        150        160        170        180 
VKEKTGLVID AYFSSPKIKW ILDNVPEARK KAEQGKLLFG TVDTWLIWNL TGRKVHATDY 

       190        200        210        220        230        240 
TNASRTMLFN IKNLDWDDEL LEIMNIPRNM LPKPLPSSYF YGVCNIFEDA EIPITGIAGD 

       250        260        270        280        290        300 
QQAALFGQCG FEEGILKNTY GTGCFILLNT GKDIKYSSKG LITTVAYGIG DDVHYALEGS 

       310        320        330        340        350        360 
VFIAGAVIQW LRDNLGIIKN SSESEILAKM VEDNGGVYFV PAFVGLGAPY WDMFARGLII 

       370        380        390        400        410        420 
GITRGVKREH IVRAALESIA YQTNDVIELM ESETGIKIKE LRVDGGASAN NFLMQFQSDI 

       430        440        450        460        470        480 
SNLKVVRPYI TETTSLGAAF LAGLKVGIWK DLNEIKRIWR EEKIFTPGMP EEKRRYYLAK 

       490 
WKEAVTKARG WEKE

« Hide

References

[1]"The complete genome sequence of Dictyoglomus thermophilum strain ATCC 35947 / DSM 3960 / H-6-12."
Dodson R.J., Durkin A.S., Wu M., Eisen J., Sutton G.
Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001146 Genomic DNA. Translation: ACI19444.1.
RefSeqYP_002250556.1. NC_011297.1.

3D structure databases

ProteinModelPortalB5YDE8.
ModBaseSearch...

Protein-protein interaction databases

STRINGB5YDE8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6945692.
GenomeReviewsGene locus DICTH_0684 in contig CP001146_GR.
KEGGdth:DICTH_0684.
PATRIC21806012. VBIDicThe33784_0679.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG511469.
OMAALYGQLC.
ProtClustDBCLSK2409744.

Family and domain databases

HAMAPMF_00186. Glycerol_kin.
[Tree]
InterProIPR000577. Carb_kinase_FGGY.
IPR018485. Carb_kinase_FGGY_C.
IPR018483. Carb_kinase_FGGY_CS.
IPR018484. Carb_kinase_FGGY_N.
IPR005999. Glycerol_kin.
[Graphical view]
KOK00864.
PANTHERPTHR10196. FGGY_kin. 1 hit.
PTHR10196:SF9. Glycerol_kin. 1 hit.
PfamPF02782. FGGY_C. 1 hit.
PF00370. FGGY_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR01311. Glycerol_kin. 1 hit.
PROSITEPS00933. FGGY_KINASES_1. 1 hit.
PS00445. FGGY_KINASES_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB5YDE8_DICT6
AccessionPrimary (citable) accession number: B5YDE8
Entry history
Integrated into UniProtKB/TrEMBL: November 25, 2008
Last sequence update: November 25, 2008
Last modified: December 14, 2011
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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