B5YDC7 (B5YDC7_DICT6) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
UDP-3-0-acyl N-acetylglucosamine deacetylase EMBL ACI20066.1
EC=3.5.1.- EMBL ACI20066.1

Gene names

Name:	lpxC EMBL ACI20066.1
Ordered Locus Names:	DICTH_0662

Organism

Dictyoglomus thermophilum (strain ATCC 35947 / DSM 3960 / H-6-12) [Complete proteome] [HAMAP]

Taxonomic identifier

309799 [NCBI]

Taxonomic lineage

Bacteria › Dictyoglomi › Dictyoglomales › Dictyoglomaceae › Dictyoglomus

Protein attributes

Sequence length	279 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS015870
Catalytic activity	UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine + H2O = UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine + acetate. SAAS SAAS015870
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6. SAAS SAAS015870

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS015870 Lipid synthesis
Molecular function	Hydrolase SAAS SAAS015870 EMBL ACI20066.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B5YDC7 [UniParc]. Last modified November 25, 2008. Version 1. Checksum: 58DBA01CBC82801E	FASTA	279	31,356
	10 20 30 40 50 60 MGKQATISNS FTAEGKGLHI GGFSKLTFEP APIDTGIVFI KEGIKVPALY NYVFDTKRRV 70 80 90 100 110 120 VLGNKDKLIS TVEHLLSAIY ALGISNLFIY VEGDEIPILD GSSVKWCELL YNAGIKIQDA 130 140 150 160 170 180 ERRSFSLMDS VLIRDGNGLL LLFPSERLEI LCAISFPKSF IKWQRFYLDS LDKYFNEIAP 190 200 210 220 230 240 ARTFGFYYEV EDLIKRGLIS GADLENALLV GEEGYVNLPR FFDEPVRHKI LDIIGDFSLL 250 260 270 GMDLKMRVIS IGSGHSLHIK ALEIISNKFI EGGREFERS

References

[1]	"The complete genome sequence of Dictyoglomus thermophilum strain ATCC 35947 / DSM 3960 / H-6-12." Dodson R.J., Durkin A.S., Wu M., Eisen J., Sutton G. Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001146 Genomic DNA. Translation: ACI20066.1.
RefSeq	YP_002250535.1. NC_011297.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B5YDC7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6946490.
GenomeReviews	Gene locus DICTH_0662 in contig CP001146_GR.
KEGG	dth:DICTH_0662.
PATRIC	21805968. VBIDicThe33784_0658.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG482342.
OMA	KAYKSGH.
ProtClustDB	CLSK2410107.
Family and domain databases
InterPro	IPR020568. Ribosomal_S5_D2-typ_fold. IPR004463. UDP-acyl_GlcNac_deAcase. IPR011334. UDP-acyl_GlcNac_deAcase_C. IPR015870. UDP-acyl_N-AcGlcN_deAcase_N. [Graphical view]
Gene3D	G3DSA:3.30.1700.10. UDP-acyl_N-AcGlcN_deAcase_C. 1 hit. G3DSA:3.30.230.20. UDP-acyl_N-AcGlcN_deAcase_N. 1 hit.
KO	K02535.
Pfam	PF03331. LpxC. 1 hit. [Graphical view]
SUPFAM	SSF54211. Ribosomal_S5_D2-typ_fold. 2 hits.
TIGRFAMs	TIGR00325. LpxC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B5YDC7_DICT6

Accession

Primary (citable) accession number: B5YDC7

Entry history

Integrated into UniProtKB/TrEMBL:	November 25, 2008
Last sequence update:	November 25, 2008
Last modified:	December 14, 2011
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)