B5Y8K7 (DCD_COPPD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	COPRO5265_0757

Organism

Coprothermobacter proteolyticus (strain ATCC 35245 / DSM 5265 / BT) [Complete proteome] [HAMAP]

Taxonomic identifier

309798 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Clostridia › Thermoanaerobacterales › Thermodesulfobiaceae › Coprothermobacter › Coprothermobacter proteolyticus

Protein attributes

Sequence length	186 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP-Rule MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP-Rule MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	dUMP biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 186	186	Deoxycytidine triphosphate deaminase HAMAP-Rule MF_00146		PRO_1000096417

Sequences

	Sequence		Length	Mass (Da)
	B5Y8K7 [UniParc]. Last modified November 25, 2008. Version 1. Checksum: FB6BE771C787D626	FASTA	186	20,704
	10 20 30 40 50 60 MILSDGLIKE LISYRALVIE PLSETQIQPS SVDLTLGSTF LAIDNINVPF LDPKRKETIK 70 80 90 100 110 120 YREIHIEKGG QLILQPGFFL LGTTTERLML PNFLVARVEG RSSLGRMGIL IHATAGYVDP 130 140 150 160 170 180 GFCGQITLEI SNVNNIPVAL YPGMRICQVS FELLFENCVI PYGLKGKYQG QEGPEGTRIF LDFLKE

References

[1]

"The complete genome sequence of Coprothermobacter proteolyticus strain ATCC 5245 / DSM 5265 / BT." Dodson R.J., Durkin A.S., Wu M., Eisen J., Sutton G. Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 35245 / DSM 5265 / BT.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001145 Genomic DNA. Translation: ACI17836.1.
RefSeq	YP_002247104.1. NC_011295.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	309798.COPRO5265_0757.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACI17836; ACI17836; COPRO5265_0757.
GeneID	6944703.
KEGG	cpo:COPRO5265_0757.
PATRIC	21474346. VBICopPro72829_0716.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0717.
HOGENOM	HOG000228601.
KO	K01494.
OMA	GSFAWVD.
Enzyme and pathway databases
BioCyc	CPRO309798:GH7M-1063-MONOMER.
UniPathway	UPA00610; UER00665.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase.
InterPro	IPR011962. dCTP_deam. IPR010550. dCTP_deam_bac. [Graphical view]
Pfam	PF06559. DCD. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_COPPD

Accession

Primary (citable) accession number: B5Y8K7

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	November 25, 2008
Last modified:	May 1, 2013
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program