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Protein

dCTP deaminase

Gene

dcd

Organism
Coprothermobacter proteolyticus (strain ATCC 35245 / DSM 5265 / BT)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

dCTP + H2O = dUTP + NH3.UniRule annotation

Pathwayi: dUMP biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes dUMP from dCTP (dUTP route).UniRule annotation
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. dCTP deaminase (dcd)
  2. no protein annotated in this organism
This subpathway is part of the pathway dUMP biosynthesis, which is itself part of Pyrimidine metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes dUMP from dCTP (dUTP route), the pathway dUMP biosynthesis and in Pyrimidine metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Nucleotide metabolism

Enzyme and pathway databases

UniPathwayiUPA00610; UER00665.

Names & Taxonomyi

Protein namesi
Recommended name:
dCTP deaminaseUniRule annotation (EC:3.5.4.13UniRule annotation)
Alternative name(s):
Deoxycytidine triphosphate deaminaseUniRule annotation
Gene namesi
Name:dcdUniRule annotation
Ordered Locus Names:COPRO5265_0757
OrganismiCoprothermobacter proteolyticus (strain ATCC 35245 / DSM 5265 / BT)
Taxonomic identifieri309798 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaThermoanaerobacteralesThermodesulfobiaceaeCoprothermobacter
Proteomesi
  • UP000001732 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000964171 – 186dCTP deaminaseAdd BLAST186

Interactioni

Protein-protein interaction databases

STRINGi309798.COPRO5265_0757.

Structurei

3D structure databases

ProteinModelPortaliB5Y8K7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the dCTP deaminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DHP. Bacteria.
COG0717. LUCA.
HOGENOMiHOG000228601.
KOiK01494.
OMAiGWIDAGF.
OrthoDBiPOG091H021I.

Family and domain databases

CDDicd07557. trimeric_dUTPase. 1 hit.
Gene3Di2.70.40.10. 1 hit.
HAMAPiMF_00146. dCTP_deaminase. 1 hit.
InterProiIPR011962. dCTP_deam.
IPR010550. dCTP_deam_bac.
IPR029054. dUTPase-like.
IPR033704. dUTPase_trimeric.
[Graphical view]
PfamiPF06559. DCD. 1 hit.
[Graphical view]
SUPFAMiSSF51283. SSF51283. 1 hit.
TIGRFAMsiTIGR02274. dCTP_deam. 1 hit.

Sequencei

Sequence statusi: Complete.

B5Y8K7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MILSDGLIKE LISYRALVIE PLSETQIQPS SVDLTLGSTF LAIDNINVPF
60 70 80 90 100
LDPKRKETIK YREIHIEKGG QLILQPGFFL LGTTTERLML PNFLVARVEG
110 120 130 140 150
RSSLGRMGIL IHATAGYVDP GFCGQITLEI SNVNNIPVAL YPGMRICQVS
160 170 180
FELLFENCVI PYGLKGKYQG QEGPEGTRIF LDFLKE
Length:186
Mass (Da):20,704
Last modified:November 25, 2008 - v1
Checksum:iFB6BE771C787D626
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001145 Genomic DNA. Translation: ACI17836.1.
RefSeqiWP_012544487.1. NC_011295.1.

Genome annotation databases

EnsemblBacteriaiACI17836; ACI17836; COPRO5265_0757.
KEGGicpo:COPRO5265_0757.
PATRICi21474346. VBICopPro72829_0716.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001145 Genomic DNA. Translation: ACI17836.1.
RefSeqiWP_012544487.1. NC_011295.1.

3D structure databases

ProteinModelPortaliB5Y8K7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi309798.COPRO5265_0757.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACI17836; ACI17836; COPRO5265_0757.
KEGGicpo:COPRO5265_0757.
PATRICi21474346. VBICopPro72829_0716.

Phylogenomic databases

eggNOGiENOG4105DHP. Bacteria.
COG0717. LUCA.
HOGENOMiHOG000228601.
KOiK01494.
OMAiGWIDAGF.
OrthoDBiPOG091H021I.

Enzyme and pathway databases

UniPathwayiUPA00610; UER00665.

Family and domain databases

CDDicd07557. trimeric_dUTPase. 1 hit.
Gene3Di2.70.40.10. 1 hit.
HAMAPiMF_00146. dCTP_deaminase. 1 hit.
InterProiIPR011962. dCTP_deam.
IPR010550. dCTP_deam_bac.
IPR029054. dUTPase-like.
IPR033704. dUTPase_trimeric.
[Graphical view]
PfamiPF06559. DCD. 1 hit.
[Graphical view]
SUPFAMiSSF51283. SSF51283. 1 hit.
TIGRFAMsiTIGR02274. dCTP_deam. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiDCD_COPPD
AccessioniPrimary (citable) accession number: B5Y8K7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: November 25, 2008
Last modified: November 30, 2016
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.