Reviewed, UniProtKB/Swiss-Prot B5Y7V5 (SYGA_COPPD)

Names and origin

Protein names

Recommended name:
    Glycyl-tRNA synthetase alpha subunit
    EC=6.1.1.14
Alternative name(s):
    Glycine--tRNA ligase alpha subunit
      Short name=GlyRS

Gene names

Name:	glyQ
Ordered Locus Names:	COPRO5265_0493

Organism

Coprothermobacter proteolyticus (strain ATCC 35245 / DSM 5265 / BT) [Complete proteome] [HAMAP]

Taxonomic identifier

309798 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Thermoanaerobacterales › Thermodesulfobiaceae › Coprothermobacter

Protein attributes

Sequence length	291 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP MF_00254
Subunit structure	Tetramer of two alpha and two beta subunits By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP glycine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 291	291	Glycyl-tRNA synthetase alpha subunit HAMAP MF_00254		PRO_1000101177

Sequences

	Sequence		Length	Mass (Da)
	B5Y7V5-1 [UniParc]. Last modified November 25, 2008. Version 1. Checksum: 61B07FCD71051AA5	FASTA	291	34,068
	10 20 30 40 50 60 MTFQELITNL TDFWIKQGCI LAQPYDVEVG AGTMNPNTFF RVLGPEPWRV VYVEPSRRPA 70 80 90 100 110 120 DGRYGENPNR LYMHHQMQVI LKPAPFNVQD LYLQSLEAIG ISLSEHDVRF VEDNWESPTL 130 140 150 160 170 180 GAWGIGWEVW LDGMEITQFT YFQQAGGYDL SVVPAELTYG LERIAMYLQR VENVFDLKWS 190 200 210 220 230 240 EDITYGEMRK TEEYQHCVYA FEESDVNKLR SWFDSYEDEA MRLIDKGLTL PAYDYVLKCS 250 260 270 280 290 HTFNLLDARG GFSAAERSSY VLRIRKLSSR IAKQWLKERE EKEFPLMGRW N

References

[1]	"The complete genome sequence of Coprothermobacter proteolyticus strain ATCC 5245 / DSM 5265 / BT." Dodson R.J., Durkin A.S., Wu M., Eisen J., Sutton G. Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP001145 Genomic DNA. Translation: ACI17775.1.
RefSeq	YP_002246852.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6944607.
GenomeReviews	Gene locus COPRO5265_0493 in contig CP001145_GR.
KEGG	cpo:COPRO5265_0493.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	CRRPTDG.
Family and domain databases
HAMAP	MF_00254. [Tree]
InterPro	IPR006194. Gly-tRNA-synth_II_heterodimer. IPR002310. Gly-tRNA_synth_IIc_asu. [Graphical view]
Pfam	PF02091. tRNA-synt_2e. 1 hit. [Graphical view]
PRINTS	PR01044. TRNASYNTHGA.
TIGRFAMs	TIGR00388. glyQ. 1 hit.
PROSITE	PS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYGA_COPPD

Accession

Primary (citable) accession number: B5Y7V5

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	November 25, 2008
Last modified:	November 3, 2009
This is version 9 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)