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Protein

Type-2 restriction enzyme

Gene

hsdR

Organism
Coprothermobacter proteolyticus (strain ATCC 35245 / DSM 5265 / BT)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Recognizes the double-stranded unmethylated sequence GATC and cleaves before G-1.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonucleaseUniRule annotation, Hydrolase, Nuclease
Biological processRestriction systemUniRule annotation

Enzyme and pathway databases

BioCyciCPRO309798:G1GCO-1345-MONOMER

Protein family/group databases

REBASEi18906 Cpr5265ORF1447P

Names & Taxonomyi

Protein namesi
Recommended name:
Type-2 restriction enzymeUniRule annotation (EC:3.1.21.4UniRule annotation)
Gene namesi
Name:hsdRImported
Ordered Locus Names:COPRO5265_1446Imported
OrganismiCoprothermobacter proteolyticus (strain ATCC 35245 / DSM 5265 / BT)Imported
Taxonomic identifieri309798 [NCBI]
Taxonomic lineageiBacteriaCoprothermobacterotaCoprothermobacteriaCoprothermobacteralesCoprothermobacteraceaeCoprothermobacter
Proteomesi
  • UP000001732 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi309798.COPRO5265_1446

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini20 – 303DpnIIInterPro annotationAdd BLAST284

Sequence similaritiesi

Belongs to the type II restriction enzyme DpnII family.UniRule annotation

Phylogenomic databases

eggNOGiENOG41076U0 Bacteria
ENOG410YTH4 LUCA
HOGENOMiHOG000244578
KOiK01155
OMAiGLEQIFC
OrthoDBiPOG091H023I

Family and domain databases

InterProiView protein in InterPro
IPR021191 Restrct_endonuc_II_DpmII
IPR007637 Restrct_endonuc_II_DpmII-like
PfamiView protein in Pfam
PF04556 DpnII, 1 hit
PIRSFiPIRSF016080 Restrict_endonuc_II_DpmII, 1 hit

Sequencei

Sequence statusi: Complete.

B5Y630-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKYSNLFYKL ISCKDEDDVF EYLIRNLKET IISWDFFVAW EKVINKVEDI
60 70 80 90 100
EISLNLLNYL VGKENITEKF AELVSKYPEV IDVLPVLVAW RAKNVKVLDP
110 120 130 140 150
LDDNIFNYKE YSFEKKSSYT TEEIASLTEF ADKTGLLAMF KNENIKSVVD
160 170 180 190 200
YVTGVEVGLD TNARKNRSGA AMEMITELLI KRICAKNRYN YISQATAHKI
210 220 230 240 250
NELFGYEVKV DKSERSFDFA IDNGDKLYLV ETNYYGGGGS KLKAVAGEFV
260 270 280 290 300
TLCRFLKRET PQHTFIWITD GLGWKTAKKP LREAFDEVDY ILNLSMLENG
310
VLENIILEGL
Length:310
Mass (Da):35,679
Last modified:November 25, 2008 - v1
Checksum:iBA5EA283488D44EA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001145 Genomic DNA Translation: ACI17600.1
RefSeqiWP_012544252.1, NC_011295.1

Genome annotation databases

EnsemblBacteriaiACI17600; ACI17600; COPRO5265_1446
KEGGicpo:COPRO5265_1446

Similar proteinsi

Entry informationi

Entry nameiB5Y630_COPPD
AccessioniPrimary (citable) accession number: B5Y630
Entry historyiIntegrated into UniProtKB/TrEMBL: November 25, 2008
Last sequence update: November 25, 2008
Last modified: May 23, 2018
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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