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B5Y3V2

- B5Y3V2_PHATC

UniProt

B5Y3V2 - B5Y3V2_PHATC

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Protein

DNA ligase

Gene

PHATR_51005

Organism
Phaeodactylum tricornutum (strain CCAP 1055/1)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: InterPro
  2. DNA ligation involved in DNA repair Source: InterPro
  3. DNA recombination Source: UniProtKB-KW
  4. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:PHATR_51005Imported
OrganismiPhaeodactylum tricornutum (strain CCAP 1055/1)Imported
Taxonomic identifieri556484 [NCBI]
Taxonomic lineageiEukaryotaStramenopilesBacillariophytaBacillariophyceaeBacillariophycidaeNaviculalesPhaeodactylaceaePhaeodactylum
ProteomesiUP000000759: Chromosome 11

Interactioni

Protein-protein interaction databases

STRINGi2850.JGI51005.

Structurei

3D structure databases

ProteinModelPortaliB5Y3V2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000036006.
InParanoidiB5Y3V2.
KOiK10747.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B5Y3V2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPYSVLCQAF TDIEAVTSRL LIQQIFTTLL RQIAVQNPVD LYPVLYLASN
60 70 80 90 100
DVAPAYECVE LGVGDSILVR AIGEATGTNP AMVKKRYEEI GDLGDVAKSF
110 120 130 140 150
KSKQRTLGGF FQKSVAPKKP LTAAQVLHVF REIAQTKGNQ SQKWKVENIK
160 170 180 190 200
KLIVQATEAT ETKYIVRGLQ GKLRIGLAQS TVLIGLAHAL ALTPPITLCP
210 220 230 240 250
HQPTLAELED YPAEARQYLD DTLPSEKRME AAVAIVKKAY SEVPSYDAIV
260 270 280 290 300
NGAAKVPLHQ LHRACTLTPG IPVAPMLAKP TKSIQEVLKR LSGLRFTCEY
310 320 330 340 350
KYDGERAQVH LLPDGTTRVF SRNLLDTSEK YPEVPLFVKE ACRNVESFVL
360 370 380 390 400
DAEVVAYNNK TGQLVPFQIL STRKKTEESA ETAKVQVIVQ AFDLMYLNGK
410 420 430 440 450
SLLNQTLAAR RSLLMEHFEA VPGKFQFAKS LDHKEDGDTT VLEEFLDSAV
460 470 480 490 500
KGQCEGLMVK TLEVNAIYEP SRRSLNWLKL KKDYLDGLGD SVDLVPLGAY
510 520 530 540 550
HGRGKRTGFY GAYLLACYDS ETEEFQSVCK IGTGFSEEDL KSLAENLNQH
560 570 580 590 600
VIPTKSQQYS VSDVLECDVW FDAVQVWEIK AADLSKSSTH RGAEGKTGEE
610 620 630 640 650
GRGIGLRFPR FERIRDDKRP EEATTSDQIL EMYYQQDAIA GNDDDVEDDG

I
Length:651
Mass (Da):72,330
Last modified:November 25, 2008 - v1
Checksum:i5D75D42E604851D4
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001141 Genomic DNA. Translation: ACI65374.1.
RefSeqiXP_002185904.1. XM_002185868.1.
UniGeneiPtc.7514.

Genome annotation databases

EnsemblProtistsiPhatr51005; Phatr51005; Phatr51005.
GeneIDi7204673.
KEGGipti:PHATR_51005.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001141 Genomic DNA. Translation: ACI65374.1 .
RefSeqi XP_002185904.1. XM_002185868.1.
UniGenei Ptc.7514.

3D structure databases

ProteinModelPortali B5Y3V2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 2850.JGI51005.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblProtistsi Phatr51005 ; Phatr51005 ; Phatr51005 .
GeneIDi 7204673.
KEGGi pti:PHATR_51005.

Phylogenomic databases

HOGENOMi HOG000036006.
InParanoidi B5Y3V2.
KOi K10747.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProi IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The Phaeodactylum genome reveals the evolutionary history of diatom genomes."
    Bowler C., Allen A.E., Badger J.H., Grimwood J., Jabbari K., Kuo A., Maheswari U., Martens C., Maumus F., Otillar R.P., Rayko E., Salamov A., Vandepoele K., Beszteri B., Gruber A., Heijde M., Katinka M., Mock T.
    , Valentin K., Verret F., Berges J.A., Brownlee C., Cadoret J.P., Chiovitti A., Choi C.J., Coesel S., De Martino A., Detter J.C., Durkin C., Falciatore A., Fournet J., Haruta M., Huysman M.J., Jenkins B.D., Jiroutova K., Jorgensen R.E., Joubert Y., Kaplan A., Kroger N., Kroth P.G., La Roche J., Lindquist E., Lommer M., Martin-Jezequel V., Lopez P.J., Lucas S., Mangogna M., McGinnis K., Medlin L.K., Montsant A., Oudot-Le Secq M.P., Napoli C., Obornik M., Parker M.S., Petit J.L., Porcel B.M., Poulsen N., Robison M., Rychlewski L., Rynearson T.A., Schmutz J., Shapiro H., Siaut M., Stanley M., Sussman M.R., Taylor A.R., Vardi A., von Dassow P., Vyverman W., Willis A., Wyrwicz L.S., Rokhsar D.S., Weissenbach J., Armbrust E.V., Green B.R., Van de Peer Y., Grigoriev I.V.
    Nature 456:239-244(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CCAP 1055/1Imported.
  2. Cited for: GENOME REANNOTATION.
    Strain: CCAP 1055/1Imported.

Entry informationi

Entry nameiB5Y3V2_PHATC
AccessioniPrimary (citable) accession number: B5Y3V2
Entry historyi
Integrated into UniProtKB/TrEMBL: November 25, 2008
Last sequence update: November 25, 2008
Last modified: October 29, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3