B5Y3V2 (B5Y3V2_PHATC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
DNA ligase RuleBase RU000617
EC=6.5.1.1 RuleBase RU000617

Gene names

ORF Names:

PHATR_51005 EMBL ACI65374.1

Organism

Phaeodactylum tricornutum (strain CCAP 1055/1) [Reference proteome]

Taxonomic identifier

556484 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Stramenopiles › Bacillariophyta › Bacillariophyceae › Bacillariophycidae › Naviculales › Phaeodactylaceae › Phaeodactylum › Phaeodactylum tricornutum

Protein attributes

Sequence length	651 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). RuleBase RU000617
Sequence similarities	Belongs to the ATP-dependent DNA ligase family. RuleBase RU004196

Ontologies

Keywords
Biological process	DNA damage DNA recombination RuleBase RU000617 DNA repair RuleBase RU000617 DNA replication RuleBase RU000617
Ligand	ATP-binding RuleBase RU000617 Nucleotide-binding
Molecular function	Ligase RuleBase RU000617
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	DNA ligation involved in DNA repair Inferred from electronic annotation. Source: InterPro DNA recombination Inferred from electronic annotation. Source: UniProtKB-KW DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA binding Inferred from electronic annotation. Source: InterPro DNA ligase (ATP) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B5Y3V2 [UniParc]. Last modified November 25, 2008. Version 1. Checksum: 5D75D42E604851D4	FASTA	651	72,330
	10 20 30 40 50 60 MPYSVLCQAF TDIEAVTSRL LIQQIFTTLL RQIAVQNPVD LYPVLYLASN DVAPAYECVE 70 80 90 100 110 120 LGVGDSILVR AIGEATGTNP AMVKKRYEEI GDLGDVAKSF KSKQRTLGGF FQKSVAPKKP 130 140 150 160 170 180 LTAAQVLHVF REIAQTKGNQ SQKWKVENIK KLIVQATEAT ETKYIVRGLQ GKLRIGLAQS 190 200 210 220 230 240 TVLIGLAHAL ALTPPITLCP HQPTLAELED YPAEARQYLD DTLPSEKRME AAVAIVKKAY 250 260 270 280 290 300 SEVPSYDAIV NGAAKVPLHQ LHRACTLTPG IPVAPMLAKP TKSIQEVLKR LSGLRFTCEY 310 320 330 340 350 360 KYDGERAQVH LLPDGTTRVF SRNLLDTSEK YPEVPLFVKE ACRNVESFVL DAEVVAYNNK 370 380 390 400 410 420 TGQLVPFQIL STRKKTEESA ETAKVQVIVQ AFDLMYLNGK SLLNQTLAAR RSLLMEHFEA 430 440 450 460 470 480 VPGKFQFAKS LDHKEDGDTT VLEEFLDSAV KGQCEGLMVK TLEVNAIYEP SRRSLNWLKL 490 500 510 520 530 540 KKDYLDGLGD SVDLVPLGAY HGRGKRTGFY GAYLLACYDS ETEEFQSVCK IGTGFSEEDL 550 560 570 580 590 600 KSLAENLNQH VIPTKSQQYS VSDVLECDVW FDAVQVWEIK AADLSKSSTH RGAEGKTGEE 610 620 630 640 650 GRGIGLRFPR FERIRDDKRP EEATTSDQIL EMYYQQDAIA GNDDDVEDDG I

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The Phaeodactylum genome reveals the evolutionary history of diatom genomes." Bowler C., Allen A.E., Badger J.H., Grimwood J., Jabbari K., Kuo A., Maheswari U., Martens C., Maumus F., Otillar R.P., Rayko E., Salamov A., Vandepoele K., Beszteri B., Gruber A., Heijde M., Katinka M., Mock T. , Valentin K., Verret F., Berges J.A., Brownlee C., Cadoret J.P., Chiovitti A., Choi C.J., Coesel S., De Martino A., Detter J.C., Durkin C., Falciatore A., Fournet J., Haruta M., Huysman M.J., Jenkins B.D., Jiroutova K., Jorgensen R.E., Joubert Y., Kaplan A., Kroger N., Kroth P.G., La Roche J., Lindquist E., Lommer M., Martin-Jezequel V., Lopez P.J., Lucas S., Mangogna M., McGinnis K., Medlin L.K., Montsant A., Oudot-Le Secq M.P., Napoli C., Obornik M., Parker M.S., Petit J.L., Porcel B.M., Poulsen N., Robison M., Rychlewski L., Rynearson T.A., Schmutz J., Shapiro H., Siaut M., Stanley M., Sussman M.R., Taylor A.R., Vardi A., von Dassow P., Vyverman W., Willis A., Wyrwicz L.S., Rokhsar D.S., Weissenbach J., Armbrust E.V., Green B.R., Van de Peer Y., Grigoriev I.V. Nature 456:239-244(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CCAP 1055/1 EMBL ACI65374.1.
[2]	Diatom Consortium Grigoriev I., Grimwood J., Kuo A., Otillar R.P., Salamov A., Detter J.C., Lindquist E., Shapiro H., Lucas S., Glavina del Rio T., Pitluck S., Rokhsar D., Bowler C. Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: CCAP 1055/1 EMBL ACI65374.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001141 Genomic DNA. Translation: ACI65374.1.
RefSeq	XP_002185904.1. XM_002185868.1.
UniGene	Ptc.7514.
3D structure databases
ProteinModelPortal	B5Y3V2.
ModBase	Search...
Protein-protein interaction databases
STRING	2850.JGI51005.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblProtists	Phatr51005; Phatr51005; Phatr51005.
GeneID	7204673.
KEGG	pti:PHATR_51005.
Phylogenomic databases
HOGENOM	HOG000036006.
KO	K10747.
ProtClustDB	CLSN2711193.
Family and domain databases
Gene3D	1.10.3260.10. 1 hit. 2.40.50.140. 1 hit.
InterPro	IPR000977. DNA_ligase_ATP-dep. IPR012309. DNA_ligase_ATP-dep_C. IPR012310. DNA_ligase_ATP-dep_cent. IPR016059. DNA_ligase_ATP-dep_CS. IPR012308. DNA_ligase_ATP-dep_N. IPR012340. NA-bd_OB-fold. [Graphical view]
Pfam	PF04679. DNA_ligase_A_C. 1 hit. PF01068. DNA_ligase_A_M. 1 hit. PF04675. DNA_ligase_A_N. 1 hit. [Graphical view]
SUPFAM	SSF50249. Nucleic_acid_OB. 1 hit. SSF117018. SSF117018. 1 hit.
TIGRFAMs	TIGR00574. dnl1. 1 hit.
PROSITE	PS00697. DNA_LIGASE_A1. 1 hit. PS00333. DNA_LIGASE_A2. 1 hit. PS50160. DNA_LIGASE_A3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B5Y3V2_PHATC

Accession

Primary (citable) accession number: B5Y3V2

Entry history

Integrated into UniProtKB/TrEMBL:	November 25, 2008
Last sequence update:	November 25, 2008
Last modified:	April 3, 2013
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)