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Protein

Glycerol-3-phosphate dehydrogenase [NAD(+)]

Gene

PHATR_36821

Organism
Phaeodactylum tricornutum (strain CCAP 1055/1)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei134 – 1341SubstrateUniRule annotation
Active sitei223 – 2231Proton acceptorUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Ligandi

NADUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase [NAD(+)]UniRule annotation (EC:1.1.1.8UniRule annotation)
Gene namesi
ORF Names:PHATR_36821Imported
OrganismiPhaeodactylum tricornutum (strain CCAP 1055/1)Imported
Taxonomic identifieri556484 [NCBI]
Taxonomic lineageiEukaryotaStramenopilesBacillariophytaBacillariophyceaeBacillariophycidaeNaviculalesPhaeodactylaceaePhaeodactylum
ProteomesiUP000000759 Componenti: Chromosome 11

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi2850.Phatr36821.

Structurei

3D structure databases

ProteinModelPortaliB5Y3R9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni287 – 2882Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000246855.
InParanoidiB5Y3R9.
KOiK00006.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR013328. 6PGD_dom_2.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR11728. PTHR11728. 1 hit.
PfamiPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.
TIGRFAMsiTIGR03376. glycerol3P_DH. 1 hit.
PROSITEiPS00957. NAD_G3PDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B5Y3R9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSNPQNSSD QLDKVCIIGS GNWGSAIATL VGRNCERLPF FESQVNMWVF
60 70 80 90 100
EEMVELEDGS QKKLTEIINS RHENVKYLPG IPLPSNVVAT PDLAEACRDA
110 120 130 140 150
TLLIFVLPHQ FLPRLLPVIR ESAHPTCRGV SLIKGLDFDS ERKLPILISN
160 170 180 190 200
TIADAMGPEF QCGVLMGANV ASEVALGQMC ESTLASPFGP PADELTRLVF
210 220 230 240 250
DAPSFRVQHV PDVAGAEVCG ALKNVVALGA GFVDGVGLGS NTKAALLRVG
260 270 280 290 300
LREMAKFCHM FFDGVQDNTF TQSCGMADLI TTCYGGRNRK CAEAFAKERL
310 320 330 340 350
GSDGLCDEAM ACEQKWEKIE AKLLNGQKLQ GTLTAKEVHA ILDSRGVLNA
360 370 380
FPLIKTIHEI SFKGKPVQQI VDGIIDTNEH GASSHL
Length:386
Mass (Da):41,740
Last modified:November 25, 2008 - v1
Checksum:i4A7282AAF2608FB5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001141 Genomic DNA. Translation: ACI65357.1.
RefSeqiXP_002185887.1. XM_002185851.1.
UniGeneiPtc.5681.

Genome annotation databases

GeneIDi7204657.
KEGGipti:PHATR_36821.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001141 Genomic DNA. Translation: ACI65357.1.
RefSeqiXP_002185887.1. XM_002185851.1.
UniGeneiPtc.5681.

3D structure databases

ProteinModelPortaliB5Y3R9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi2850.Phatr36821.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi7204657.
KEGGipti:PHATR_36821.

Phylogenomic databases

HOGENOMiHOG000246855.
InParanoidiB5Y3R9.
KOiK00006.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR013328. 6PGD_dom_2.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR11728. PTHR11728. 1 hit.
PfamiPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.
TIGRFAMsiTIGR03376. glycerol3P_DH. 1 hit.
PROSITEiPS00957. NAD_G3PDH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The Phaeodactylum genome reveals the evolutionary history of diatom genomes."
    Bowler C., Allen A.E., Badger J.H., Grimwood J., Jabbari K., Kuo A., Maheswari U., Martens C., Maumus F., Otillar R.P., Rayko E., Salamov A., Vandepoele K., Beszteri B., Gruber A., Heijde M., Katinka M., Mock T.
    , Valentin K., Verret F., Berges J.A., Brownlee C., Cadoret J.P., Chiovitti A., Choi C.J., Coesel S., De Martino A., Detter J.C., Durkin C., Falciatore A., Fournet J., Haruta M., Huysman M.J., Jenkins B.D., Jiroutova K., Jorgensen R.E., Joubert Y., Kaplan A., Kroger N., Kroth P.G., La Roche J., Lindquist E., Lommer M., Martin-Jezequel V., Lopez P.J., Lucas S., Mangogna M., McGinnis K., Medlin L.K., Montsant A., Oudot-Le Secq M.P., Napoli C., Obornik M., Parker M.S., Petit J.L., Porcel B.M., Poulsen N., Robison M., Rychlewski L., Rynearson T.A., Schmutz J., Shapiro H., Siaut M., Stanley M., Sussman M.R., Taylor A.R., Vardi A., von Dassow P., Vyverman W., Willis A., Wyrwicz L.S., Rokhsar D.S., Weissenbach J., Armbrust E.V., Green B.R., Van de Peer Y., Grigoriev I.V.
    Nature 456:239-244(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CCAP 1055/1Imported.
  2. Cited for: GENOME REANNOTATION.
    Strain: CCAP 1055/1Imported.

Entry informationi

Entry nameiB5Y3R9_PHATC
AccessioniPrimary (citable) accession number: B5Y3R9
Entry historyi
Integrated into UniProtKB/TrEMBL: November 25, 2008
Last sequence update: November 25, 2008
Last modified: June 24, 2015
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.