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B5Y0Y9

- ACPH_KLEP3

UniProt

B5Y0Y9 - ACPH_KLEP3

Protein

Acyl carrier protein phosphodiesterase

Gene

acpH

Organism
Klebsiella pneumoniae (strain 342)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 35 (01 Oct 2014)
      Sequence version 1 (25 Nov 2008)
      Previous versions | rss
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    • Comment

    Functioni

    Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP.UniRule annotation

    Catalytic activityi

    Holo-[acyl-carrier-protein] + H2O = 4'-phosphopantetheine + apo-[acyl-carrier-protein].UniRule annotation

    GO - Molecular functioni

    1. [acyl-carrier-protein] phosphodiesterase activity Source: UniProtKB-EC

    GO - Biological processi

    1. fatty acid biosynthetic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism

    Enzyme and pathway databases

    BioCyciKPNE507522:GI0B-4331-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Acyl carrier protein phosphodiesteraseUniRule annotation (EC:3.1.4.14UniRule annotation)
    Short name:
    ACP phosphodiesteraseUniRule annotation
    Gene namesi
    Name:acpHUniRule annotation
    Ordered Locus Names:KPK_4330
    OrganismiKlebsiella pneumoniae (strain 342)
    Taxonomic identifieri507522 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
    ProteomesiUP000001734: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 193193Acyl carrier protein phosphodiesterasePRO_1000188809Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi507522.KPK_4330.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the AcpH family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG3124.
    HOGENOMiHOG000275880.
    KOiK08682.
    OMAiWLHRQID.
    OrthoDBiEOG6K6V7H.

    Family and domain databases

    HAMAPiMF_01950. AcpH.
    InterProiIPR007431. ACP_phosphodiesterase.
    IPR023491. ACP_phosphodiesterase_gpbac.
    [Graphical view]
    PfamiPF04336. DUF479. 1 hit.
    [Graphical view]
    PIRSFiPIRSF011489. DUF479. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B5Y0Y9-1 [UniParc]FASTAAdd to Basket

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    MNFLAHLHLA HLADSSLPGN LMADFVRGNP QGDYPAEIID GIYMHRRIDV    50
    MTDNLAEVKE AREWFRPQTR RVAPITLDVM WDHFLSQHWA QLSPDLPLDE 100
    FVRYAEQQIV PILPDSPPRF VNLNQYLWSE RWLERYQEMD FIQRVLNGMA 150
    SRRPRLDALR DSWQDLDTHY DQLEGQFWRF YPQMMRLAEN KQL 193
    Length:193
    Mass (Da):23,110
    Last modified:November 25, 2008 - v1
    Checksum:iD646BE41F732A76E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000964 Genomic DNA. Translation: ACI10473.1.
    RefSeqiYP_002240130.1. NC_011283.1.

    Genome annotation databases

    EnsemblBacteriaiACI10473; ACI10473; KPK_4330.
    GeneIDi6938065.
    KEGGikpe:KPK_4330.
    PATRICi20441868. VBIKlePne121904_4284.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000964 Genomic DNA. Translation: ACI10473.1 .
    RefSeqi YP_002240130.1. NC_011283.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 507522.KPK_4330.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACI10473 ; ACI10473 ; KPK_4330 .
    GeneIDi 6938065.
    KEGGi kpe:KPK_4330.
    PATRICi 20441868. VBIKlePne121904_4284.

    Phylogenomic databases

    eggNOGi COG3124.
    HOGENOMi HOG000275880.
    KOi K08682.
    OMAi WLHRQID.
    OrthoDBi EOG6K6V7H.

    Enzyme and pathway databases

    BioCyci KPNE507522:GI0B-4331-MONOMER.

    Family and domain databases

    HAMAPi MF_01950. AcpH.
    InterProi IPR007431. ACP_phosphodiesterase.
    IPR023491. ACP_phosphodiesterase_gpbac.
    [Graphical view ]
    Pfami PF04336. DUF479. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF011489. DUF479. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of the N2-fixing broad host range endophyte Klebsiella pneumoniae 342 and virulence predictions verified in mice."
      Fouts D.E., Tyler H.L., DeBoy R.T., Daugherty S., Ren Q., Badger J.H., Durkin A.S., Huot H., Shrivastava S., Kothari S., Dodson R.J., Mohamoud Y., Khouri H., Roesch L.F.W., Krogfelt K.A., Struve C., Triplett E.W., Methe B.A.
      PLoS Genet. 4:E1000141-E1000141(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 342.

    Entry informationi

    Entry nameiACPH_KLEP3
    AccessioniPrimary (citable) accession number: B5Y0Y9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 28, 2009
    Last sequence update: November 25, 2008
    Last modified: October 1, 2014
    This is version 35 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3