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B5Y0Y9 (ACPH_KLEP3) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Acyl carrier protein phosphodiesterase

Short name=ACP phosphodiesterase
EC=3.1.4.14
Gene names
Name:acpH
Ordered Locus Names:KPK_4330
OrganismKlebsiella pneumoniae (strain 342) [Complete proteome] [HAMAP]
Taxonomic identifier507522 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella

Protein attributes

Sequence length193 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP By similarity. HAMAP-Rule MF_01950

Catalytic activity

Holo-[acyl-carrier-protein] + H2O = 4'-phosphopantetheine + apo-[acyl-carrier-protein]. HAMAP-Rule MF_01950

Sequence similarities

Belongs to the AcpH family.

Ontologies

Keywords
   Biological processFatty acid biosynthesis
Fatty acid metabolism
Lipid biosynthesis
Lipid metabolism
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processfatty acid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_function[acyl-carrier-protein] phosphodiesterase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 193193Acyl carrier protein phosphodiesterase HAMAP-Rule MF_01950
PRO_1000188809

Sequences

Sequence LengthMass (Da)Tools
B5Y0Y9 [UniParc].

Last modified November 25, 2008. Version 1.
Checksum: D646BE41F732A76E

FASTA19323,110
        10         20         30         40         50         60 
MNFLAHLHLA HLADSSLPGN LMADFVRGNP QGDYPAEIID GIYMHRRIDV MTDNLAEVKE 

        70         80         90        100        110        120 
AREWFRPQTR RVAPITLDVM WDHFLSQHWA QLSPDLPLDE FVRYAEQQIV PILPDSPPRF 

       130        140        150        160        170        180 
VNLNQYLWSE RWLERYQEMD FIQRVLNGMA SRRPRLDALR DSWQDLDTHY DQLEGQFWRF 

       190 
YPQMMRLAEN KQL 

« Hide

References

[1]"Complete genome sequence of the N2-fixing broad host range endophyte Klebsiella pneumoniae 342 and virulence predictions verified in mice."
Fouts D.E., Tyler H.L., DeBoy R.T., Daugherty S., Ren Q., Badger J.H., Durkin A.S., Huot H., Shrivastava S., Kothari S., Dodson R.J., Mohamoud Y., Khouri H., Roesch L.F.W., Krogfelt K.A., Struve C., Triplett E.W., Methe B.A.
PLoS Genet. 4:E1000141-E1000141(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 342.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000964 Genomic DNA. Translation: ACI10473.1.
RefSeqYP_002240130.1. NC_011283.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING507522.KPK_4330.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACI10473; ACI10473; KPK_4330.
GeneID6938065.
KEGGkpe:KPK_4330.
PATRIC20441868. VBIKlePne121904_4284.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG3124.
HOGENOMHOG000275880.
KOK08682.
OMAWLHRQID.
OrthoDBEOG6K6V7H.
ProtClustDBPRK10045.

Enzyme and pathway databases

BioCycKPNE507522:GI0B-4331-MONOMER.

Family and domain databases

HAMAPMF_01950. AcpH.
InterProIPR007431. ACP_phosphodiesterase.
IPR023491. ACP_phosphodiesterase_gpbac.
[Graphical view]
PfamPF04336. DUF479. 1 hit.
[Graphical view]
PIRSFPIRSF011489. DUF479. 1 hit.
ProtoNetSearch...

Entry information

Entry nameACPH_KLEP3
AccessionPrimary (citable) accession number: B5Y0Y9
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: November 25, 2008
Last modified: February 19, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families