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B5Y0Y9

- ACPH_KLEP3

UniProt

B5Y0Y9 - ACPH_KLEP3

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Protein

Acyl carrier protein phosphodiesterase

Gene

acpH

Organism
Klebsiella pneumoniae (strain 342)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP.UniRule annotation

Catalytic activityi

Holo-[acyl-carrier-protein] + H2O = 4'-phosphopantetheine + apo-[acyl-carrier-protein].UniRule annotation

GO - Molecular functioni

  1. [acyl-carrier-protein] phosphodiesterase activity Source: UniProtKB-EC

GO - Biological processi

  1. fatty acid biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism

Enzyme and pathway databases

BioCyciKPNE507522:GI0B-4331-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Acyl carrier protein phosphodiesteraseUniRule annotation (EC:3.1.4.14UniRule annotation)
Short name:
ACP phosphodiesteraseUniRule annotation
Gene namesi
Name:acpHUniRule annotation
Ordered Locus Names:KPK_4330
OrganismiKlebsiella pneumoniae (strain 342)
Taxonomic identifieri507522 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
ProteomesiUP000001734: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 193193Acyl carrier protein phosphodiesterasePRO_1000188809Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi507522.KPK_4330.

Family & Domainsi

Sequence similaritiesi

Belongs to the AcpH family.UniRule annotation

Phylogenomic databases

eggNOGiCOG3124.
HOGENOMiHOG000275880.
KOiK08682.
OMAiWLHRQID.
OrthoDBiEOG6K6V7H.

Family and domain databases

HAMAPiMF_01950. AcpH.
InterProiIPR007431. ACP_phosphodiesterase.
IPR023491. ACP_phosphodiesterase_gpbac.
[Graphical view]
PfamiPF04336. DUF479. 1 hit.
[Graphical view]
PIRSFiPIRSF011489. DUF479. 1 hit.

Sequencei

Sequence statusi: Complete.

B5Y0Y9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNFLAHLHLA HLADSSLPGN LMADFVRGNP QGDYPAEIID GIYMHRRIDV
60 70 80 90 100
MTDNLAEVKE AREWFRPQTR RVAPITLDVM WDHFLSQHWA QLSPDLPLDE
110 120 130 140 150
FVRYAEQQIV PILPDSPPRF VNLNQYLWSE RWLERYQEMD FIQRVLNGMA
160 170 180 190
SRRPRLDALR DSWQDLDTHY DQLEGQFWRF YPQMMRLAEN KQL
Length:193
Mass (Da):23,110
Last modified:November 25, 2008 - v1
Checksum:iD646BE41F732A76E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000964 Genomic DNA. Translation: ACI10473.1.
RefSeqiYP_002240130.1. NC_011283.1.

Genome annotation databases

EnsemblBacteriaiACI10473; ACI10473; KPK_4330.
GeneIDi6938065.
KEGGikpe:KPK_4330.
PATRICi20441868. VBIKlePne121904_4284.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000964 Genomic DNA. Translation: ACI10473.1 .
RefSeqi YP_002240130.1. NC_011283.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 507522.KPK_4330.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACI10473 ; ACI10473 ; KPK_4330 .
GeneIDi 6938065.
KEGGi kpe:KPK_4330.
PATRICi 20441868. VBIKlePne121904_4284.

Phylogenomic databases

eggNOGi COG3124.
HOGENOMi HOG000275880.
KOi K08682.
OMAi WLHRQID.
OrthoDBi EOG6K6V7H.

Enzyme and pathway databases

BioCyci KPNE507522:GI0B-4331-MONOMER.

Family and domain databases

HAMAPi MF_01950. AcpH.
InterProi IPR007431. ACP_phosphodiesterase.
IPR023491. ACP_phosphodiesterase_gpbac.
[Graphical view ]
Pfami PF04336. DUF479. 1 hit.
[Graphical view ]
PIRSFi PIRSF011489. DUF479. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of the N2-fixing broad host range endophyte Klebsiella pneumoniae 342 and virulence predictions verified in mice."
    Fouts D.E., Tyler H.L., DeBoy R.T., Daugherty S., Ren Q., Badger J.H., Durkin A.S., Huot H., Shrivastava S., Kothari S., Dodson R.J., Mohamoud Y., Khouri H., Roesch L.F.W., Krogfelt K.A., Struve C., Triplett E.W., Methe B.A.
    PLoS Genet. 4:E1000141-E1000141(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 342.

Entry informationi

Entry nameiACPH_KLEP3
AccessioniPrimary (citable) accession number: B5Y0Y9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: November 25, 2008
Last modified: October 1, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3