B5Y0Y9 (ACPH_KLEP3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acyl carrier protein phosphodiesterase
Short name=ACP phosphodiesterase
EC=3.1.4.14

Gene names

Name:	acpH
Ordered Locus Names:	KPK_4330

Organism

Klebsiella pneumoniae (strain 342) [Complete proteome] [HAMAP]

Taxonomic identifier

507522 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Klebsiella › Klebsiella pneumoniae

Protein attributes

Sequence length	193 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP By similarity. HAMAP-Rule MF_01950
Catalytic activity	Holo-[acyl-carrier-protein] + H2O = 4'-phosphopantetheine + apo-[acyl-carrier-protein]. HAMAP-Rule MF_01950
Sequence similarities	Belongs to the AcpH family.

Ontologies

Keywords
Biological process	Fatty acid biosynthesis Fatty acid metabolism Lipid biosynthesis Lipid metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	fatty acid biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	[acyl-carrier-protein] phosphodiesterase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 193	193	Acyl carrier protein phosphodiesterase HAMAP-Rule MF_01950		PRO_1000188809

Sequences

	Sequence		Length	Mass (Da)
	B5Y0Y9 [UniParc]. Last modified November 25, 2008. Version 1. Checksum: D646BE41F732A76E	FASTA	193	23,110
	10 20 30 40 50 60 MNFLAHLHLA HLADSSLPGN LMADFVRGNP QGDYPAEIID GIYMHRRIDV MTDNLAEVKE 70 80 90 100 110 120 AREWFRPQTR RVAPITLDVM WDHFLSQHWA QLSPDLPLDE FVRYAEQQIV PILPDSPPRF 130 140 150 160 170 180 VNLNQYLWSE RWLERYQEMD FIQRVLNGMA SRRPRLDALR DSWQDLDTHY DQLEGQFWRF 190 YPQMMRLAEN KQL

References

[1]

"Complete genome sequence of the N2-fixing broad host range endophyte Klebsiella pneumoniae 342 and virulence predictions verified in mice." Fouts D.E., Tyler H.L., DeBoy R.T., Daugherty S., Ren Q., Badger J.H., Durkin A.S., Huot H., Shrivastava S., Kothari S., Dodson R.J., Mohamoud Y., Khouri H., Roesch L.F.W., Krogfelt K.A., Struve C., Triplett E.W., Methe B.A. PLoS Genet. 4:E1000141-E1000141(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 342.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000964 Genomic DNA. Translation: ACI10473.1.
RefSeq	YP_002240130.1. NC_011283.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	507522.KPK_4330.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACI10473; ACI10473; KPK_4330.
GeneID	6938065.
KEGG	kpe:KPK_4330.
PATRIC	20441868. VBIKlePne121904_4284.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3124.
HOGENOM	HOG000275880.
KO	K08682.
OMA	WLHRQID.
ProtClustDB	PRK10045.
Enzyme and pathway databases
BioCyc	KPNE507522:GI0B-3946-MONOMER.
Family and domain databases
HAMAP	MF_01950. AcpH.
InterPro	IPR007431. ACP_phosphodiesterase. IPR023491. ACP_phosphodiesterase_gpbac. [Graphical view]
Pfam	PF04336. DUF479. 1 hit. [Graphical view]
PIRSF	PIRSF011489. DUF479. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ACPH_KLEP3

Accession

Primary (citable) accession number: B5Y0Y9

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	November 25, 2008
Last modified:	May 1, 2013
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program