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B5XZ20

- CAPP_KLEP3

UniProt

B5XZ20 - CAPP_KLEP3

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Protein

Phosphoenolpyruvate carboxylase

Gene
ppc, KPK_5436
Organism
Klebsiella pneumoniae (strain 342)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Magnesium By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381 By similarity
Active sitei546 – 5461 By similarity

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Carbon dioxide fixation

Keywords - Ligandi

Magnesium

Enzyme and pathway databases

BioCyciKPNE507522:GI0B-5437-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylase (EC:4.1.1.31)
Short name:
PEPC
Short name:
PEPCase
Gene namesi
Name:ppc
Ordered Locus Names:KPK_5436
OrganismiKlebsiella pneumoniae (strain 342)
Taxonomic identifieri507522 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
ProteomesiUP000001734: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 883883Phosphoenolpyruvate carboxylaseUniRule annotationPRO_1000129835Add
BLAST

Proteomic databases

PRIDEiB5XZ20.

Interactioni

Protein-protein interaction databases

STRINGi507522.KPK_5436.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238648.
KOiK01595.
OMAiELSTISC.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B5XZ20-1 [UniParc]FASTAAdd to Basket

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MNEQYSALRS NVSMLGKVLG DTIKDALGEN ILDRVETIRK LSKSSRAGNE    50
ANRQELLTTL QNLSNDELLP VARAFSQFLN LANTAEQYHS ISPNGEAASN 100
PEVIARTLRK LKDQPNLNED TIKKAVESLS LELVLTAHPT EITRRTLIHK 150
MVEVNSCLKQ LDNKDIADYE HHQLMRRLRQ LIAQSWHTDE IRKYRPSPVD 200
EAKWGFAVVE NSLWEGVPNY LRELNEQLEA NLGYQLPVDF VPVRFTSWMG 250
GDRDGNPNVT ADITRHVLLL SRWKATDLFL KDVQVLISEL SMVECTDELR 300
ALAGAEGAQE PYRYLMKKLR TQLMETQAWL EARLKGQKLP KPAGLITQNE 350
QLWEPLYACY KSLQACGMGI IANGELLDTL RRVKSFGVPL VRIDIRQEST 400
RHTEALGEMT RYLGIGDYES WSEADKQAFL IRELNSKRPL LPRQWEPSEE 450
TREVLDTCKV IAEAPRGSIA AYVISMAKTP SDVLAVHLLL KEAGIGFALP 500
VAPLFETLDD LNNANDVMTQ LLNIDWYRGF IQGKQMVMIG YSDSAKDAGV 550
MAASWAQYQA QDALIKTCEK AGIELTLFHG RGGSIGRGGA PAHAALLSQP 600
PGSLKGGLRV TEQGEMIRFK YGLPEVTISS LSLYTSAILE ANLLPPPEPK 650
AEWRDIMAEL SDVSCKMYRG YVRENKDFVP YFRSATPEQE LGKLPLGSRP 700
AKRRPTGGVE SLRAIPWIFA WTQNRLMLPA WLGAGAALQK VVEGGKQSEL 750
EAMCRDWPFF STRLGMLEMV YSKADLWLAE YYDQRLVKPE LWALGTELRK 800
LLAADINVVL AIANDSHLMA DLPWIAESIQ LRNIYTDPLN VLQAELLHRS 850
RQAEEAGKDP DPRVEQALMV TIAGVAAGMR NTG 883
Length:883
Mass (Da):98,927
Last modified:November 25, 2008 - v1
Checksum:i59E08657975BA510
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000964 Genomic DNA. Translation: ACI08563.1.
RefSeqiYP_002241183.1. NC_011283.1.

Genome annotation databases

EnsemblBacteriaiACI08563; ACI08563; KPK_5436.
GeneIDi6935920.
KEGGikpe:KPK_5436.
PATRICi20443964. VBIKlePne121904_5286.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000964 Genomic DNA. Translation: ACI08563.1 .
RefSeqi YP_002241183.1. NC_011283.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 507522.KPK_5436.

Proteomic databases

PRIDEi B5XZ20.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACI08563 ; ACI08563 ; KPK_5436 .
GeneIDi 6935920.
KEGGi kpe:KPK_5436.
PATRICi 20443964. VBIKlePne121904_5286.

Phylogenomic databases

eggNOGi COG2352.
HOGENOMi HOG000238648.
KOi K01595.
OMAi ELSTISC.
OrthoDBi EOG6TJ7T8.

Enzyme and pathway databases

BioCyci KPNE507522:GI0B-5437-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of the N2-fixing broad host range endophyte Klebsiella pneumoniae 342 and virulence predictions verified in mice."
    Fouts D.E., Tyler H.L., DeBoy R.T., Daugherty S., Ren Q., Badger J.H., Durkin A.S., Huot H., Shrivastava S., Kothari S., Dodson R.J., Mohamoud Y., Khouri H., Roesch L.F.W., Krogfelt K.A., Struve C., Triplett E.W., Methe B.A.
    PLoS Genet. 4:E1000141-E1000141(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 342.

Entry informationi

Entry nameiCAPP_KLEP3
AccessioniPrimary (citable) accession number: B5XZ20
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: November 25, 2008
Last modified: May 14, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi