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Protein

Adenylate cyclase

Gene

cyaA

Organism
Klebsiella pneumoniae (strain 342)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP = 3',5'-cyclic AMP + diphosphate.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationImported

Keywords - Biological processi

cAMP biosynthesisUniRule annotation

Enzyme and pathway databases

BioCyciKPNE507522:GI0B-5374-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Adenylate cyclaseUniRule annotation (EC:4.6.1.1UniRule annotation)
Gene namesi
Name:cyaAImported
Ordered Locus Names:KPK_5373Imported
OrganismiKlebsiella pneumoniae (strain 342)Imported
Taxonomic identifieri507522 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
ProteomesiUP000001734 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Family & Domainsi

Sequence similaritiesi

Belongs to the adenylyl cyclase class-1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG3072.
HOGENOMiHOG000270910.
KOiK05851.
OMAiSEGFLQF.
OrthoDBiEOG63JR9H.

Family and domain databases

InterProiIPR000274. Adenylate_cyclase_1.
IPR024686. Adenylate_cyclase_1_CS.
IPR024685. Adenylate_cyclase_1_N.
[Graphical view]
PfamiPF12633. Adenyl_cycl_N. 1 hit.
PF01295. Adenylate_cycl. 1 hit.
[Graphical view]
PIRSFiPIRSF001444. Adenylate_cycl. 1 hit.
PROSITEiPS01092. ADENYLATE_CYCLASE_1_1. 1 hit.
PS01093. ADENYLATE_CYCLASE_1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B5XYL0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYLYIETLKQ RLDAINQLRV DRALAAMGPA FQQVYSLLPT LLHYHHPLMP
60 70 80 90 100
GYLDGNVPRG ICLYTPDETQ RHYLEELELH RGMQTQEPPK GELPITGVYS
110 120 130 140 150
MGSTSSVGQS CSSDLDIWVC HQAWLDSEER QLLQRKCSLL ESWAASLGVE
160 170 180 190 200
VSFFLIDENR FRHNESGSLG GEDCGSTQHI LLLDEFYRTA VRLAGKRILW
210 220 230 240 250
NMVPCDEEEH YDDYVMGLYA QGVLTPNEWL DLGGLSSLSA EEYFGASLWQ
260 270 280 290 300
LYKSIDSPYK AVLKTLLLEA YSWEYPNNRL LAKDIKQRLH DGEIVSFGLD
310 320 330 340 350
PYCMMLERVT TYLQAIEDET RLDLVRRCFY LKVCEKLSRE RACVGWRREV
360 370 380 390 400
VSQLVNAWGW DEKRLMMLDN RANWKIDEVR KAHNELLDAM MQSYRNLIRF
410 420 430 440 450
ARRNNLSVSA SPQDIGVLTR KLYAAFEALP GKVTLVNPQI SPDLSEPNLT
460 470 480 490 500
FIHVPPGRAN RTGWYLYNRA PDMESIISHQ PLEYNRYLNK LVAWAWFNGL
510 520 530 540 550
LTSRTRLFIK GNGIVDLAKL QEMVADVSHH FPLRLPAPTP KALYSPCEIR
560 570 580 590 600
HLAIIVNLEY DPTAAFRNQV VHFDFRKLDV FSFGEEQKCL IGSVDLLYRN
610 620 630 640 650
SWNEVRTLHF NGEQAMIEAL KTILGKMHQD AAPPDSVEVF CYSQHLRGLI
660 670 680 690 700
RTRVQQMISE CIELRLSSTR QDTGRFKALR VSGQTWGLFF ERLNVSVQKL
710 720 730 740 750
ENAIEFYGAI SHNKLHGLSV QVETNHVKLP AVVDGFASEG IIQFFFEDAD
760 770 780 790 800
NNDSGFNIYI LDESNRAEVY HHCEGSKEEL VRDVSRFYSS SHDRFTYGSS
810 820 830 840 850
FINFNLPQFY QIVEVDGRTQ VIPFRTQAIA AAIPTSQDVT ASPVLQQRYS
Length:850
Mass (Da):97,571
Last modified:November 25, 2008 - v1
Checksum:iCD6A99E02CD00314
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000964 Genomic DNA. Translation: ACI06625.1.
RefSeqiWP_002883383.1. NC_011283.1.

Genome annotation databases

EnsemblBacteriaiACI06625; ACI06625; KPK_5373.
KEGGikpe:KPK_5373.
PATRICi20443844. VBIKlePne121904_5237.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000964 Genomic DNA. Translation: ACI06625.1.
RefSeqiWP_002883383.1. NC_011283.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACI06625; ACI06625; KPK_5373.
KEGGikpe:KPK_5373.
PATRICi20443844. VBIKlePne121904_5237.

Phylogenomic databases

eggNOGiCOG3072.
HOGENOMiHOG000270910.
KOiK05851.
OMAiSEGFLQF.
OrthoDBiEOG63JR9H.

Enzyme and pathway databases

BioCyciKPNE507522:GI0B-5374-MONOMER.

Family and domain databases

InterProiIPR000274. Adenylate_cyclase_1.
IPR024686. Adenylate_cyclase_1_CS.
IPR024685. Adenylate_cyclase_1_N.
[Graphical view]
PfamiPF12633. Adenyl_cycl_N. 1 hit.
PF01295. Adenylate_cycl. 1 hit.
[Graphical view]
PIRSFiPIRSF001444. Adenylate_cycl. 1 hit.
PROSITEiPS01092. ADENYLATE_CYCLASE_1_1. 1 hit.
PS01093. ADENYLATE_CYCLASE_1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of the N2-fixing broad host range endophyte Klebsiella pneumoniae 342 and virulence predictions verified in mice."
    Fouts D.E., Tyler H.L., DeBoy R.T., Daugherty S., Ren Q., Badger J.H., Durkin A.S., Huot H., Shrivastava S., Kothari S., Dodson R.J., Mohamoud Y., Khouri H., Roesch L.F.W., Krogfelt K.A., Struve C., Triplett E.W., Methe B.A.
    PLoS Genet. 4:E1000141-E1000141(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 342Imported.

Entry informationi

Entry nameiB5XYL0_KLEP3
AccessioniPrimary (citable) accession number: B5XYL0
Entry historyi
Integrated into UniProtKB/TrEMBL: November 25, 2008
Last sequence update: November 25, 2008
Last modified: July 22, 2015
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.