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Protein

FMN reductase (NADH) RutF

Gene

rutF

Organism
Klebsiella pneumoniae (strain 342)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway.UniRule annotation

Catalytic activityi

FMNH2 + NAD+ = FMN + NADH.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

Flavoprotein, FMN, NAD

Enzyme and pathway databases

BioCyciKPNE507522:GI0B-3526-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
FMN reductase (NADH) RutFUniRule annotation (EC:1.5.1.42UniRule annotation)
Alternative name(s):
FMN reductaseUniRule annotation
NADH-flavin reductase RutFUniRule annotation
NADH:flavin oxidoreductaseUniRule annotation
Gene namesi
Name:rutFUniRule annotation
Ordered Locus Names:KPK_3525
OrganismiKlebsiella pneumoniae (strain 342)
Taxonomic identifieri507522 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
Proteomesi
  • UP000001734 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 164164FMN reductase (NADH) RutFPRO_0000403028Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliB5XXN5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the non-flavoprotein flavin reductase family. RutF subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000115783.
KOiK09024.
OMAiWFDRGYH.
OrthoDBiEOG6T1WSH.

Family and domain databases

Gene3Di2.30.110.10. 1 hit.
HAMAPiMF_00833. RutF.
InterProiIPR002563. Flavin_Rdtase-like_dom.
IPR019917. RutF.
IPR012349. Split_barrel_FMN-bd.
[Graphical view]
PfamiPF01613. Flavin_Reduct. 1 hit.
[Graphical view]
SMARTiSM00903. Flavin_Reduct. 1 hit.
[Graphical view]
SUPFAMiSSF50475. SSF50475. 1 hit.
TIGRFAMsiTIGR03615. RutF. 1 hit.

Sequencei

Sequence statusi: Complete.

B5XXN5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELADKASFR DAMAHVGAAV NIITTDGPAG RAGFTASAVC SVTDTPPTLL
60 70 80 90 100
VCLNRSASVW PVFSEHHTLC VNTLAAGQEA LSTLFGGKTA MDERFAAADW
110 120 130 140 150
QTGATGCPRL EAALVSFDCR IDQRVSVGTH DILFCHVVAI TRHPEPRGLM
160
WFGRGYHTLM RPAC
Length:164
Mass (Da):17,546
Last modified:November 25, 2008 - v1
Checksum:i04FDB6CE9A1F9078
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000964 Genomic DNA. Translation: ACI10535.1.
RefSeqiWP_012542270.1. NC_011283.1.

Genome annotation databases

EnsemblBacteriaiACI10535; ACI10535; KPK_3525.
KEGGikpe:KPK_3525.
PATRICi20440341. VBIKlePne121904_3539.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000964 Genomic DNA. Translation: ACI10535.1.
RefSeqiWP_012542270.1. NC_011283.1.

3D structure databases

ProteinModelPortaliB5XXN5.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACI10535; ACI10535; KPK_3525.
KEGGikpe:KPK_3525.
PATRICi20440341. VBIKlePne121904_3539.

Phylogenomic databases

HOGENOMiHOG000115783.
KOiK09024.
OMAiWFDRGYH.
OrthoDBiEOG6T1WSH.

Enzyme and pathway databases

BioCyciKPNE507522:GI0B-3526-MONOMER.

Family and domain databases

Gene3Di2.30.110.10. 1 hit.
HAMAPiMF_00833. RutF.
InterProiIPR002563. Flavin_Rdtase-like_dom.
IPR019917. RutF.
IPR012349. Split_barrel_FMN-bd.
[Graphical view]
PfamiPF01613. Flavin_Reduct. 1 hit.
[Graphical view]
SMARTiSM00903. Flavin_Reduct. 1 hit.
[Graphical view]
SUPFAMiSSF50475. SSF50475. 1 hit.
TIGRFAMsiTIGR03615. RutF. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of the N2-fixing broad host range endophyte Klebsiella pneumoniae 342 and virulence predictions verified in mice."
    Fouts D.E., Tyler H.L., DeBoy R.T., Daugherty S., Ren Q., Badger J.H., Durkin A.S., Huot H., Shrivastava S., Kothari S., Dodson R.J., Mohamoud Y., Khouri H., Roesch L.F.W., Krogfelt K.A., Struve C., Triplett E.W., Methe B.A.
    PLoS Genet. 4:E1000141-E1000141(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 342.

Entry informationi

Entry nameiRUTF_KLEP3
AccessioniPrimary (citable) accession number: B5XXN5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 11, 2011
Last sequence update: November 25, 2008
Last modified: November 11, 2015
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.