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B5XQU5

- UXAB_KLEP3

UniProt

B5XQU5 - UXAB_KLEP3

Protein

Altronate oxidoreductase

Gene

uxaB

Organism
Klebsiella pneumoniae (strain 342)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 42 (01 Oct 2014)
      Sequence version 1 (25 Nov 2008)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-altronate + NAD+ = D-tagaturonate + NADH.UniRule annotation

    Pathwayi

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi18 – 2912NADUniRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. coenzyme binding Source: InterPro
    2. tagaturonate reductase activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Ligandi

    NAD

    Enzyme and pathway databases

    BioCyciKPNE507522:GI0B-2740-MONOMER.
    UniPathwayiUPA00246.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Altronate oxidoreductaseUniRule annotation (EC:1.1.1.58UniRule annotation)
    Alternative name(s):
    Tagaturonate dehydrogenaseUniRule annotation
    Tagaturonate reductaseUniRule annotation
    Gene namesi
    Name:uxaBUniRule annotation
    Ordered Locus Names:KPK_2739
    OrganismiKlebsiella pneumoniae (strain 342)
    Taxonomic identifieri507522 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
    ProteomesiUP000001734: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 483483Altronate oxidoreductasePRO_1000131514Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi507522.KPK_2739.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the mannitol dehydrogenase family. UxaB subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0246.
    HOGENOMiHOG000029586.
    KOiK00041.
    OMAiHNTFCST.
    OrthoDBiEOG6CVVB8.

    Family and domain databases

    Gene3Di1.10.1040.10. 1 hit.
    3.40.50.720. 1 hit.
    HAMAPiMF_00670. Altron_oxidoreduct.
    InterProiIPR008927. 6-PGluconate_DH_C-like.
    IPR023668. Altronate_OxRdtase.
    IPR013328. DH_multihelical.
    IPR013118. Mannitol_DH_C.
    IPR013131. Mannitol_DH_N.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view]
    PfamiPF01232. Mannitol_dh. 1 hit.
    PF08125. Mannitol_dh_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF48179. SSF48179. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B5XQU5-1 [UniParc]FASTAAdd to Basket

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    MKTLNRRDFP GAQYPDRIIQ FGEGNFLRAF VDWQIDLLNE HTDLNAGIVV    50
    VRPIATDFPP SLSTQDGLYT TIIRGLNEQG EAVSDARLIR SVNREISAYA 100
    DFDAFLRLAH NPEMRFVFSN TTEAGISYHA GDRFDDAPPV SYPAKLTRLL 150
    FERYQHFAGA ADKGWVIIPC ELIDYNGEAL QALVLRYAAE WQLPQAFIRW 200
    LTSANTFCST LVDRIVTGYP RDEVAALEAQ TGYKDAFLDT AEHFYLFVIQ 250
    GPASLAAELR LDKLPLNVRI VDDIKPYKER KVAILNGAHT ALVPVAFLAG 300
    IDTVGEAMND AEICAFVEKA IYDEIIPVLD LPRDELESFA SAVTGRFRNP 350
    YIKHQLLSIA LNGMTKYRTR ILPQLLAGQQ KSGQLPPRLT FALAALIAFY 400
    RGEREGERYP VQDDAEWLAR YQTLWARHRD RQMSTRELVT AVLSVEAHWE 450
    QDLSQIPGLV EQVTADLDAI LSRGMRDAVQ PLC 483
    Length:483
    Mass (Da):54,393
    Last modified:November 25, 2008 - v1
    Checksum:i2A09B068A2DB14B0
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000964 Genomic DNA. Translation: ACI08566.1.
    RefSeqiWP_012541766.1. NC_011283.1.
    YP_002238569.1. NC_011283.1.

    Genome annotation databases

    EnsemblBacteriaiACI08566; ACI08566; KPK_2739.
    GeneIDi6937326.
    KEGGikpe:KPK_2739.
    PATRICi20438886. VBIKlePne121904_2815.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000964 Genomic DNA. Translation: ACI08566.1 .
    RefSeqi WP_012541766.1. NC_011283.1.
    YP_002238569.1. NC_011283.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 507522.KPK_2739.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACI08566 ; ACI08566 ; KPK_2739 .
    GeneIDi 6937326.
    KEGGi kpe:KPK_2739.
    PATRICi 20438886. VBIKlePne121904_2815.

    Phylogenomic databases

    eggNOGi COG0246.
    HOGENOMi HOG000029586.
    KOi K00041.
    OMAi HNTFCST.
    OrthoDBi EOG6CVVB8.

    Enzyme and pathway databases

    UniPathwayi UPA00246 .
    BioCyci KPNE507522:GI0B-2740-MONOMER.

    Family and domain databases

    Gene3Di 1.10.1040.10. 1 hit.
    3.40.50.720. 1 hit.
    HAMAPi MF_00670. Altron_oxidoreduct.
    InterProi IPR008927. 6-PGluconate_DH_C-like.
    IPR023668. Altronate_OxRdtase.
    IPR013328. DH_multihelical.
    IPR013118. Mannitol_DH_C.
    IPR013131. Mannitol_DH_N.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view ]
    Pfami PF01232. Mannitol_dh. 1 hit.
    PF08125. Mannitol_dh_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48179. SSF48179. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of the N2-fixing broad host range endophyte Klebsiella pneumoniae 342 and virulence predictions verified in mice."
      Fouts D.E., Tyler H.L., DeBoy R.T., Daugherty S., Ren Q., Badger J.H., Durkin A.S., Huot H., Shrivastava S., Kothari S., Dodson R.J., Mohamoud Y., Khouri H., Roesch L.F.W., Krogfelt K.A., Struve C., Triplett E.W., Methe B.A.
      PLoS Genet. 4:E1000141-E1000141(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 342.

    Entry informationi

    Entry nameiUXAB_KLEP3
    AccessioniPrimary (citable) accession number: B5XQU5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: November 25, 2008
    Last modified: October 1, 2014
    This is version 42 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3