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B5XQU5

- UXAB_KLEP3

UniProt

B5XQU5 - UXAB_KLEP3

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Protein

Altronate oxidoreductase

Gene
uxaB, KPK_2739
Organism
Klebsiella pneumoniae (strain 342)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-altronate + NAD+ = D-tagaturonate + NADH.UniRule annotation

Pathwayi

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi18 – 2912NAD By similarityAdd
BLAST

GO - Molecular functioni

  1. coenzyme binding Source: InterPro
  2. tagaturonate reductase activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NAD

Enzyme and pathway databases

BioCyciKPNE507522:GI0B-2740-MONOMER.
UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Altronate oxidoreductase (EC:1.1.1.58)
Alternative name(s):
Tagaturonate dehydrogenase
Tagaturonate reductase
Gene namesi
Name:uxaB
Ordered Locus Names:KPK_2739
OrganismiKlebsiella pneumoniae (strain 342)
Taxonomic identifieri507522 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
ProteomesiUP000001734: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 483483Altronate oxidoreductaseUniRule annotationPRO_1000131514Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi507522.KPK_2739.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0246.
HOGENOMiHOG000029586.
KOiK00041.
OMAiHNTFCST.
OrthoDBiEOG6CVVB8.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
HAMAPiMF_00670. Altron_oxidoreduct.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR023668. Altronate_OxRdtase.
IPR013328. DH_multihelical.
IPR013118. Mannitol_DH_C.
IPR013131. Mannitol_DH_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF01232. Mannitol_dh. 1 hit.
PF08125. Mannitol_dh_C. 1 hit.
[Graphical view]
SUPFAMiSSF48179. SSF48179. 1 hit.

Sequencei

Sequence statusi: Complete.

B5XQU5-1 [UniParc]FASTAAdd to Basket

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MKTLNRRDFP GAQYPDRIIQ FGEGNFLRAF VDWQIDLLNE HTDLNAGIVV    50
VRPIATDFPP SLSTQDGLYT TIIRGLNEQG EAVSDARLIR SVNREISAYA 100
DFDAFLRLAH NPEMRFVFSN TTEAGISYHA GDRFDDAPPV SYPAKLTRLL 150
FERYQHFAGA ADKGWVIIPC ELIDYNGEAL QALVLRYAAE WQLPQAFIRW 200
LTSANTFCST LVDRIVTGYP RDEVAALEAQ TGYKDAFLDT AEHFYLFVIQ 250
GPASLAAELR LDKLPLNVRI VDDIKPYKER KVAILNGAHT ALVPVAFLAG 300
IDTVGEAMND AEICAFVEKA IYDEIIPVLD LPRDELESFA SAVTGRFRNP 350
YIKHQLLSIA LNGMTKYRTR ILPQLLAGQQ KSGQLPPRLT FALAALIAFY 400
RGEREGERYP VQDDAEWLAR YQTLWARHRD RQMSTRELVT AVLSVEAHWE 450
QDLSQIPGLV EQVTADLDAI LSRGMRDAVQ PLC 483
Length:483
Mass (Da):54,393
Last modified:November 25, 2008 - v1
Checksum:i2A09B068A2DB14B0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000964 Genomic DNA. Translation: ACI08566.1.
RefSeqiWP_012541766.1. NC_011283.1.
YP_002238569.1. NC_011283.1.

Genome annotation databases

EnsemblBacteriaiACI08566; ACI08566; KPK_2739.
GeneIDi6937326.
KEGGikpe:KPK_2739.
PATRICi20438886. VBIKlePne121904_2815.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000964 Genomic DNA. Translation: ACI08566.1 .
RefSeqi WP_012541766.1. NC_011283.1.
YP_002238569.1. NC_011283.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 507522.KPK_2739.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACI08566 ; ACI08566 ; KPK_2739 .
GeneIDi 6937326.
KEGGi kpe:KPK_2739.
PATRICi 20438886. VBIKlePne121904_2815.

Phylogenomic databases

eggNOGi COG0246.
HOGENOMi HOG000029586.
KOi K00041.
OMAi HNTFCST.
OrthoDBi EOG6CVVB8.

Enzyme and pathway databases

UniPathwayi UPA00246 .
BioCyci KPNE507522:GI0B-2740-MONOMER.

Family and domain databases

Gene3Di 1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
HAMAPi MF_00670. Altron_oxidoreduct.
InterProi IPR008927. 6-PGluconate_DH_C-like.
IPR023668. Altronate_OxRdtase.
IPR013328. DH_multihelical.
IPR013118. Mannitol_DH_C.
IPR013131. Mannitol_DH_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view ]
Pfami PF01232. Mannitol_dh. 1 hit.
PF08125. Mannitol_dh_C. 1 hit.
[Graphical view ]
SUPFAMi SSF48179. SSF48179. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of the N2-fixing broad host range endophyte Klebsiella pneumoniae 342 and virulence predictions verified in mice."
    Fouts D.E., Tyler H.L., DeBoy R.T., Daugherty S., Ren Q., Badger J.H., Durkin A.S., Huot H., Shrivastava S., Kothari S., Dodson R.J., Mohamoud Y., Khouri H., Roesch L.F.W., Krogfelt K.A., Struve C., Triplett E.W., Methe B.A.
    PLoS Genet. 4:E1000141-E1000141(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 342.

Entry informationi

Entry nameiUXAB_KLEP3
AccessioniPrimary (citable) accession number: B5XQU5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: November 25, 2008
Last modified: September 3, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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