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B5XQU5

- UXAB_KLEP3

UniProt

B5XQU5 - UXAB_KLEP3

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Protein

Altronate oxidoreductase

Gene

uxaB

Organism
Klebsiella pneumoniae (strain 342)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-altronate + NAD+ = D-tagaturonate + NADH.UniRule annotation

Pathwayi

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi18 – 2912NADUniRule annotationAdd
BLAST

GO - Molecular functioni

  1. coenzyme binding Source: InterPro
  2. tagaturonate reductase activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NAD

Enzyme and pathway databases

BioCyciKPNE507522:GI0B-2740-MONOMER.
UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Altronate oxidoreductaseUniRule annotation (EC:1.1.1.58UniRule annotation)
Alternative name(s):
Tagaturonate dehydrogenaseUniRule annotation
Tagaturonate reductaseUniRule annotation
Gene namesi
Name:uxaBUniRule annotation
Ordered Locus Names:KPK_2739
OrganismiKlebsiella pneumoniae (strain 342)
Taxonomic identifieri507522 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
ProteomesiUP000001734: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 483483Altronate oxidoreductasePRO_1000131514Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi507522.KPK_2739.

Family & Domainsi

Sequence similaritiesi

Belongs to the mannitol dehydrogenase family. UxaB subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0246.
HOGENOMiHOG000029586.
KOiK00041.
OMAiHNTFCST.
OrthoDBiEOG6CVVB8.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
HAMAPiMF_00670. Altron_oxidoreduct.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR023668. Altronate_OxRdtase.
IPR013328. DH_multihelical.
IPR013118. Mannitol_DH_C.
IPR013131. Mannitol_DH_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF01232. Mannitol_dh. 1 hit.
PF08125. Mannitol_dh_C. 1 hit.
[Graphical view]
SUPFAMiSSF48179. SSF48179. 1 hit.

Sequencei

Sequence statusi: Complete.

B5XQU5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKTLNRRDFP GAQYPDRIIQ FGEGNFLRAF VDWQIDLLNE HTDLNAGIVV
60 70 80 90 100
VRPIATDFPP SLSTQDGLYT TIIRGLNEQG EAVSDARLIR SVNREISAYA
110 120 130 140 150
DFDAFLRLAH NPEMRFVFSN TTEAGISYHA GDRFDDAPPV SYPAKLTRLL
160 170 180 190 200
FERYQHFAGA ADKGWVIIPC ELIDYNGEAL QALVLRYAAE WQLPQAFIRW
210 220 230 240 250
LTSANTFCST LVDRIVTGYP RDEVAALEAQ TGYKDAFLDT AEHFYLFVIQ
260 270 280 290 300
GPASLAAELR LDKLPLNVRI VDDIKPYKER KVAILNGAHT ALVPVAFLAG
310 320 330 340 350
IDTVGEAMND AEICAFVEKA IYDEIIPVLD LPRDELESFA SAVTGRFRNP
360 370 380 390 400
YIKHQLLSIA LNGMTKYRTR ILPQLLAGQQ KSGQLPPRLT FALAALIAFY
410 420 430 440 450
RGEREGERYP VQDDAEWLAR YQTLWARHRD RQMSTRELVT AVLSVEAHWE
460 470 480
QDLSQIPGLV EQVTADLDAI LSRGMRDAVQ PLC
Length:483
Mass (Da):54,393
Last modified:November 25, 2008 - v1
Checksum:i2A09B068A2DB14B0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000964 Genomic DNA. Translation: ACI08566.1.
RefSeqiYP_002238569.1. NC_011283.1.

Genome annotation databases

EnsemblBacteriaiACI08566; ACI08566; KPK_2739.
GeneIDi6937326.
KEGGikpe:KPK_2739.
PATRICi20438886. VBIKlePne121904_2815.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000964 Genomic DNA. Translation: ACI08566.1 .
RefSeqi YP_002238569.1. NC_011283.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 507522.KPK_2739.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACI08566 ; ACI08566 ; KPK_2739 .
GeneIDi 6937326.
KEGGi kpe:KPK_2739.
PATRICi 20438886. VBIKlePne121904_2815.

Phylogenomic databases

eggNOGi COG0246.
HOGENOMi HOG000029586.
KOi K00041.
OMAi HNTFCST.
OrthoDBi EOG6CVVB8.

Enzyme and pathway databases

UniPathwayi UPA00246 .
BioCyci KPNE507522:GI0B-2740-MONOMER.

Family and domain databases

Gene3Di 1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
HAMAPi MF_00670. Altron_oxidoreduct.
InterProi IPR008927. 6-PGluconate_DH_C-like.
IPR023668. Altronate_OxRdtase.
IPR013328. DH_multihelical.
IPR013118. Mannitol_DH_C.
IPR013131. Mannitol_DH_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view ]
Pfami PF01232. Mannitol_dh. 1 hit.
PF08125. Mannitol_dh_C. 1 hit.
[Graphical view ]
SUPFAMi SSF48179. SSF48179. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of the N2-fixing broad host range endophyte Klebsiella pneumoniae 342 and virulence predictions verified in mice."
    Fouts D.E., Tyler H.L., DeBoy R.T., Daugherty S., Ren Q., Badger J.H., Durkin A.S., Huot H., Shrivastava S., Kothari S., Dodson R.J., Mohamoud Y., Khouri H., Roesch L.F.W., Krogfelt K.A., Struve C., Triplett E.W., Methe B.A.
    PLoS Genet. 4:E1000141-E1000141(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 342.

Entry informationi

Entry nameiUXAB_KLEP3
AccessioniPrimary (citable) accession number: B5XQU5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: November 25, 2008
Last modified: November 26, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3