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Protein

Adenine deaminase

Gene

ade

Organism
Klebsiella pneumoniae (strain 342)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Adenine + H2O = hypoxanthine + NH3.UniRule annotation

Cofactori

Mn2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Manganese

Enzyme and pathway databases

BioCyciKPNE507522:GI0B-1615-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Adenine deaminaseUniRule annotation (EC:3.5.4.2UniRule annotation)
Short name:
AdenaseUniRule annotation
Short name:
Adenine aminaseUniRule annotation
Gene namesi
Name:adeUniRule annotation
Ordered Locus Names:KPK_1614
OrganismiKlebsiella pneumoniae (strain 342)
Taxonomic identifieri507522 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
Proteomesi
  • UP000001734 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 603603Adenine deaminasePRO_1000146241Add
BLAST

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB5XP95.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the adenine deaminase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000276949.
KOiK01486.
OMAiYSHDSHN.
OrthoDBiEOG622PNM.

Family and domain databases

Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.

Sequencei

Sequence statusi: Complete.

B5XP95-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSNAQVRRR AVQAARGESP FDLLLVEAQI VDMATGEIRP ADVGIVGEMI
60 70 80 90 100
ASVHPRGSRT DAHEVRSLAG GYLSPGLMDT HVHLESSHLP PERYAEIVLT
110 120 130 140 150
QGTTAVFWDP HELANVLGVE GVRYAVDASR HLPLQVMVAA PSSVPSTPGL
160 170 180 190 200
EMSGADFAGA EMETMLGWPE VRGVAEVMDM HGVLHGSERM QEIVQAGLNS
210 220 230 240 250
GKLIEGHARG LSGADLQAYL AAGVTSDHEL TSADDALEKL RAGLTIEIRG
260 270 280 290 300
SHPYLLPDIV AALKTLPHLS SQITVCTDDV PPDMLLEKGG IIALLNLLIE
310 320 330 340 350
HGLPAVDALR FATLNAAIRL QRHDLGLIAA GRRADLVVFD SLEKLVAREV
360 370 380 390 400
YVGGERLAHA GRLLKPIAPA PGVTPPRDTL PIAPLRADDF VLRVQGIRHG
410 420 430 440 450
VARLRHIRGA RFTQWGEVEV QVRDGKVQLP AGFSLIWVKH RHGRHQATPQ
460 470 480 490 500
IALLEGWGEL RGAIATSYSH DSHNLVVLGR DADDMALAAN QLIASGGGMA
510 520 530 540 550
LAQQGEILAH VAMPIAGMLS DLPAAELARQ FRELRDLSSQ VADWEPPYRV
560 570 580 590 600
FKAIEGTCLA CNAGPHLTDL GLTDGGSRQI VDPLIACRET PEPTDHNNNP

QGA
Length:603
Mass (Da):64,605
Last modified:November 25, 2008 - v1
Checksum:iC849F6A31134B568
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000964 Genomic DNA. Translation: ACI11456.1.
RefSeqiWP_012541049.1. NC_011283.1.

Genome annotation databases

EnsemblBacteriaiACI11456; ACI11456; KPK_1614.
KEGGikpe:KPK_1614.
PATRICi20436752. VBIKlePne121904_1762.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000964 Genomic DNA. Translation: ACI11456.1.
RefSeqiWP_012541049.1. NC_011283.1.

3D structure databases

ProteinModelPortaliB5XP95.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACI11456; ACI11456; KPK_1614.
KEGGikpe:KPK_1614.
PATRICi20436752. VBIKlePne121904_1762.

Phylogenomic databases

HOGENOMiHOG000276949.
KOiK01486.
OMAiYSHDSHN.
OrthoDBiEOG622PNM.

Enzyme and pathway databases

BioCyciKPNE507522:GI0B-1615-MONOMER.

Family and domain databases

Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of the N2-fixing broad host range endophyte Klebsiella pneumoniae 342 and virulence predictions verified in mice."
    Fouts D.E., Tyler H.L., DeBoy R.T., Daugherty S., Ren Q., Badger J.H., Durkin A.S., Huot H., Shrivastava S., Kothari S., Dodson R.J., Mohamoud Y., Khouri H., Roesch L.F.W., Krogfelt K.A., Struve C., Triplett E.W., Methe B.A.
    PLoS Genet. 4:E1000141-E1000141(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 342.

Entry informationi

Entry nameiADEC_KLEP3
AccessioniPrimary (citable) accession number: B5XP95
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: November 25, 2008
Last modified: November 11, 2015
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.