B5XNU3 (B5XNU3_KLEP3) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Acetate kinase HAMAP MF_00020
EC=2.7.2.1 HAMAP MF_00020

Alternative name(s):
Acetokinase HAMAP MF_00020

Gene names

Name:	ackA HAMAP MF_00020
Ordered Locus Names:	KPK_1460

Organism

Klebsiella pneumoniae (strain 342) [Complete proteome] [HAMAP] EMBL ACI11150.1

Taxonomic identifier

507522 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Klebsiella

Protein attributes

Sequence length	400 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 SAAS SAAS000890 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020 SAAS SAAS000890
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity HAMAP MF_00020.
Sequence similarities	Belongs to the acetokinase family. HAMAP MF_00020

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00020 SAAS SAAS000890
Ligand	ATP-binding HAMAP MF_00020 SAAS SAAS000890 Nucleotide-binding
Molecular function	Kinase HAMAP MF_00020 SAAS SAAS000890 EMBL ACI11150.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B5XNU3 [UniParc]. Last modified November 25, 2008. Version 1. Checksum: 63702C2F17A6E606	FASTA	400	43,226
	10 20 30 40 50 60 MSSKLVLVLN CGSSSLKFAI LDAVNGDEYL SGLAECFHLP EARIKWKIDG GKQEAELGAG 70 80 90 100 110 120 AAHSEALNFI VNTILAQKPE LSAQLTAIGH RIVHGGEKYT SSVVIDESVI QGIKDAASFA 130 140 150 160 170 180 PLHNPAHLIG IAEALKSFPH LKDKNVAVFD TAFHQTMPEE SYLYALPYSL YKEHGVRRYG 190 200 210 220 230 240 AHGTSHFYVT QEAAKILNKP VEELNIITCH LGNGGSVSAI RNGKCVDTSM GLTPLEGLVM 250 260 270 280 290 300 GTRSGDIDPA IIFHLHDTLG MSVDAINKML TKESGLLGLT EVTSDCRYVE DNYQEKADAK 310 320 330 340 350 360 RAMDVYCHRL AKYIGSYTAL MDGRLDAVIF TGGIGENAAM VRELSLGKLG VLGFEVDHER 370 380 390 400 NLAARFGKSG FINKEGTRPA VVIPTNEELV IAQDASRLTA

References

[1]

"Complete genome sequence of the N2-fixing broad host range endophyte Klebsiella pneumoniae 342 and virulence predictions verified in mice." Fouts D.E., Tyler H.L., DeBoy R.T., Daugherty S., Ren Q., Badger J.H., Durkin A.S., Huot H., Shrivastava S., Kothari S., Dodson R.J., Mohamoud Y., Khouri H., Roesch L.F.W., Krogfelt K.A., Struve C., Triplett E.W., Methe B.A. PLoS Genet. 4:E1000141-E1000141(2008) [PubMed: 18654632] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000964 Genomic DNA. Translation: ACI11150.1.
RefSeq	YP_002237313.1. NC_011283.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B5XNU3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6939522.
GenomeReviews	Gene locus KPK_1460 in contig CP000964_GR.
KEGG	kpe:KPK_1460.
PATRIC	20436457. VBIKlePne121904_1616.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG285863.
OMA	IVFHLHD.
ProtClustDB	PRK00180.
Family and domain databases
HAMAP	MF_00020. Acetate_kinase. [Tree]
InterPro	IPR004372. Ac/Proprionate_kinase. IPR000890. Aliphatic_acid_kin_short-chain. IPR023865. Aliphatic_acid_kinase_CS. [Graphical view]
KO	K00925.
PANTHER	PTHR21060. Acetate_kin. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. AckA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B5XNU3_KLEP3

Accession

Primary (citable) accession number: B5XNU3

Entry history

Integrated into UniProtKB/TrEMBL:	November 25, 2008
Last sequence update:	November 25, 2008
Last modified:	December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)