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Protein

Ribosomal RNA small subunit methyltransferase B

Gene

rsmB

Organism
Klebsiella pneumoniae (strain 342)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + cytosine(967) in 16S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine(967) in 16S rRNA.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei277S-adenosyl-L-methionineUniRule annotation1
Binding sitei303S-adenosyl-L-methionineUniRule annotation1
Binding sitei322S-adenosyl-L-methionineUniRule annotation1
Active sitei375NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferase, RNA-binding, Transferase
Biological processrRNA processing
LigandS-adenosyl-L-methionine

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA small subunit methyltransferase BUniRule annotation (EC:2.1.1.176UniRule annotation)
Alternative name(s):
16S rRNA m5C967 methyltransferaseUniRule annotation
rRNA (cytosine-C(5)-)-methyltransferase RsmBUniRule annotation
Gene namesi
Name:rsmBUniRule annotation
Synonyms:sunUniRule annotation
Ordered Locus Names:KPK_0427
OrganismiKlebsiella pneumoniae (strain 342)
Taxonomic identifieri507522 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeKlebsiella
Proteomesi
  • UP000001734 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003661601 – 431Ribosomal RNA small subunit methyltransferase BAdd BLAST431

Structurei

3D structure databases

ProteinModelPortaliB5XNC2.
SMRiB5XNC2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni254 – 260S-adenosyl-L-methionine bindingUniRule annotation7

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000037300.
KOiK03500.
OMAiLRVNRQH.

Family and domain databases

Gene3Di1.10.940.10. 1 hit.
HAMAPiMF_01856. 16SrRNA_methyltr_B. 1 hit.
InterProiView protein in InterPro
IPR018314. Fmu/NOL1/Nop2p_CS.
IPR001678. MeTrfase_RsmB/NOP2.
IPR035926. NusB-like_sf.
IPR006027. NusB_RsmB_TIM44.
IPR023267. RCMT.
IPR004573. rRNA_ssu_MeTfrase_B.
IPR023541. rRNA_ssu_MeTfrase_B_ent.
IPR029063. SAM-dependent_MTases.
PfamiView protein in Pfam
PF01189. Methyltr_RsmB-F. 1 hit.
PF01029. NusB. 1 hit.
PRINTSiPR02008. RCMTFAMILY.
SUPFAMiSSF48013. SSF48013. 1 hit.
SSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00563. rsmB. 1 hit.
PROSITEiView protein in PROSITE
PS01153. NOL1_NOP2_SUN. 1 hit.
PS51686. SAM_MT_RSMB_NOP. 1 hit.

Sequencei

Sequence statusi: Complete.

B5XNC2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKNKINLRSL AAQAIEQVIE QGQSLSNVLP PLQQKVSDKD KALLQELCFG
60 70 80 90 100
VLRTLSQLEW LINKLMARPM TGKQRTVHFL IMVGLYQLLY TRIPPHAALA
110 120 130 140 150
ETVEGAVAIK RPQLKGLING VLRQFQRQQE ALLVEFAEHE NRYLHPKWLL
160 170 180 190 200
KRLQQAWPQQ WQEIVDANNQ RPPMWLRVNR NHHSRDEWLA LLKEAGLEGF
210 220 230 240 250
THPDYPDAVR LATPAPVHAL PGFAEGWVTV QDASAQGCMR YLLPENGERI
260 270 280 290 300
LDLCAAPGGK TTHILEVAPQ AQVMAVDIDE QRLSRVYDNL KRLGMKAEVK
310 320 330 340 350
QGDGRFPEQW CGNEQFDRIL LDAPCSATGV IRRHPDIKWL RRDRDIAELA
360 370 380 390 400
QLQAEILNST WEHLKPGGTL VYATCSILPE ENSQQISAFL ARTPDAELHA
410 420 430
TGTPASPGQQ NLPGPEEGDG FFYAKLIKRR N
Length:431
Mass (Da):48,731
Last modified:November 25, 2008 - v1
Checksum:i54E7027E6FF718A3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000964 Genomic DNA. Translation: ACI08496.1.
RefSeqiWP_012540436.1. NC_011283.1.

Genome annotation databases

EnsemblBacteriaiACI08496; ACI08496; KPK_0427.
KEGGikpe:KPK_0427.

Similar proteinsi

Entry informationi

Entry nameiRSMB_KLEP3
AccessioniPrimary (citable) accession number: B5XNC2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: November 25, 2008
Last modified: October 25, 2017
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome