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B5XLI7 (B5XLI7_STRPZ) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length189 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + thymidine = ADP + thymidine 5'-phosphate. HAMAP-Rule MF_00124 SAAS SAAS020634

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00124 SAAS SAAS020634

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00124 SAAS SAAS020634.

Sequence similarities

Belongs to the thymidine kinase family. HAMAP-Rule MF_00124 RuleBase RU004165

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding9 – 168ATP By similarity HAMAP-Rule MF_00124
Nucleotide binding85 – 884ATP By similarity HAMAP-Rule MF_00124

Sites

Active site861Proton acceptor By similarity HAMAP-Rule MF_00124
Metal binding1431Zinc By similarity HAMAP-Rule MF_00124
Metal binding1461Zinc By similarity HAMAP-Rule MF_00124
Metal binding1801Zinc By similarity HAMAP-Rule MF_00124
Metal binding1831Zinc By similarity HAMAP-Rule MF_00124

Sequences

Sequence LengthMass (Da)Tools
B5XLI7 [UniParc].

Last modified November 25, 2008. Version 1.
Checksum: BF88EE3F609B821E

FASTA18921,533
        10         20         30         40         50         60 
MAQLYYKYGT MNSGKTIEIL KVAHNYEEQG KPVVIMTSAL DTRDGFGIVS SRIGMRREAI 

        70         80         90        100        110        120 
PISNDMDIFT FIAQLEEKPY CVLIDESQFL SKQNVYDLAR VVDELNVPVM AFGLKNDFQN 

       130        140        150        160        170        180 
NLFEGSKHLL LLADKIDEIK TICQYCSKKA TMVLRTENGK PVYEGDQIQI GGNETYIPVC 


RKHYFNPDI 

« Hide

References

[1]"Genome sequence of a nephritogenic and highly transformable M49 strain of Streptococcus pyogenes."
McShan W.M., Ferretti J.J., Karasawa T., Suvorov A.N., Lin S., Qin B., Jia H., Kenton S., Najar F., Wu H., Scott J., Roe B.A., Savic D.J.
J. Bacteriol. 190:7773-7785(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NZ131 EMBL ACI61199.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000829 Genomic DNA. Translation: ACI61199.1.
RefSeqYP_002285894.1. NC_011375.1.

3D structure databases

ProteinModelPortalB5XLI7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING471876.Spy49_0893.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACI61199; ACI61199; Spy49_0893.
GeneID6985893.
KEGGsoz:Spy49_0893.
PATRIC19756839. VBIStrPyo129711_0927.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1435.
HOGENOMHOG000076391.
KOK00857.
OMAELKTVCH.
OrthoDBEOG69D3J2.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
HAMAPMF_00124. Thymidine_kinase.
InterProIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERPTHR11441. PTHR11441. 1 hit.
PfamPF00265. TK. 1 hit.
[Graphical view]
PIRSFPIRSF035805. TK_cell. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
PROSITEPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB5XLI7_STRPZ
AccessionPrimary (citable) accession number: B5XLI7
Entry history
Integrated into UniProtKB/TrEMBL: November 25, 2008
Last sequence update: November 25, 2008
Last modified: June 11, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)