B5XLC8 (B5XLC8_STRPZ) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrB HAMAP MF_01400
EC=1.8.4.12 HAMAP MF_01400

Alternative name(s):
Peptide-methionine (R)-S-oxide reductase HAMAP MF_01400

Gene names

Name:	csrA EMBL ACI61140.1
Synonyms:	msrB HAMAP MF_01400
Ordered Locus Names:	Spy49_0831

Organism

Streptococcus pyogenes serotype M49 (strain NZ131) [Complete proteome] [HAMAP]

Taxonomic identifier

471876 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length	145 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin. HAMAP MF_01400
Sequence similarities	Belongs to the MsrB Met sulfoxide reductase family. HAMAP MF_01400

Ontologies

Keywords
Molecular function	Oxidoreductase HAMAP MF_01400 SAAS SAAS002579 EMBL ACI61140.1
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	peptide-methionine (R)-S-oxide reductase activity Inferred from electronic annotation. Source: EC peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	116	1	Nucleophile By similarity HAMAP MF_01400

Sequences

	Sequence		Length	Mass (Da)
	B5XLC8 [UniParc]. Last modified November 25, 2008. Version 1. Checksum: 95E197522A4AD900	FASTA	145	16,383
	10 20 30 40 50 60 METSDELKQR IGDLSYEVTQ HAATESPFTG EYDDFFEKGI YVDIVSGEVL FSSLDKFNSG 70 80 90 100 110 120 CGWPAFSKPI ENRMVTNHDD SSYGMRRIEV KSREAGSHLG HVFSDGPKEA GGLRYCINSA 130 140 ALKFIPYEQM EKEGYAQWLT LFDET

References

[1]

"Genome sequence of a nephritogenic and highly transformable M49 strain of Streptococcus pyogenes." McShan W.M., Ferretti J.J., Karasawa T., Suvorov A.N., Lin S., Qin B., Jia H., Kenton S., Najar F., Wu H., Scott J., Roe B.A., Savic D.J. J. Bacteriol. 190:7773-7785(2008) [PubMed: 18820018] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000829 Genomic DNA. Translation: ACI61140.1.
RefSeq	YP_002285835.1. NC_011375.1.
3D structure databases
ProteinModelPortal	B5XLC8.
ModBase	Search...
Protein-protein interaction databases
STRING	B5XLC8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTRT00000050243; EBSTRP00000058902; EBSTRG00000050235.
GeneID	6985834.
GenomeReviews	Gene locus Spy49_0831 in contig CP000829_GR.
KEGG	soz:Spy49_0831.
PATRIC	19756718. VBIStrPyo129711_0867.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000027538.
HOGENOM	HBG715255.
OMA	RFIPVEK.
ProtClustDB	PRK00222.
Family and domain databases
HAMAP	MF_01400. MsrB. [Tree]
InterPro	IPR002579. Methionine_sulphoxide_MsrB. IPR011057. Mss4-like. [Graphical view]
Gene3D	G3DSA:2.170.150.20. MsrB. 1 hit.
KO	K07305.
Pfam	PF01641. SelR. 1 hit. [Graphical view]
SUPFAM	SSF51316. Mss4_like. 1 hit.
TIGRFAMs	TIGR00357. TIGR00357. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B5XLC8_STRPZ

Accession

Primary (citable) accession number: B5XLC8

Entry history

Integrated into UniProtKB/TrEMBL:	November 25, 2008
Last sequence update:	November 25, 2008
Last modified:	December 14, 2011
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)