Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

B5XKH9

- B5XKH9_STRPZ

UniProt

B5XKH9 - B5XKH9_STRPZ

Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Streptococcus pyogenes serotype M49 (strain NZ131)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 41 (01 Oct 2014)
      Sequence version 1 (25 Nov 2008)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

    Catalytic activityi

    Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

    Cofactori

    Magnesium.UniRule annotationSAAS annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei150 – 1501UniRule annotation
    Active sitei595 – 5951UniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. carbon fixation Source: UniProtKB-HAMAP
    2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
    3. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    LyaseUniRule annotationSAAS annotationImported

    Keywords - Biological processi

    Carbon dioxide fixationUniRule annotationSAAS annotation

    Keywords - Ligandi

    MagnesiumUniRule annotationSAAS annotation, PyruvateImported

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
    Short name:
    PEPCUniRule annotation
    Short name:
    PEPCaseUniRule annotation
    Gene namesi
    Name:ppcUniRule annotationImported
    Ordered Locus Names:Spy49_0513Imported
    OrganismiStreptococcus pyogenes serotype M49 (strain NZ131)Imported
    Taxonomic identifieri471876 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
    ProteomesiUP000001039: Chromosome

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Protein-protein interaction databases

    STRINGi471876.Spy49_0513.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PEPCase type 1 family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2352.
    HOGENOMiHOG000238647.
    KOiK01595.
    OMAiELSTISC.
    OrthoDBiEOG6TJ7T8.

    Family and domain databases

    HAMAPiMF_00595. PEPcase_type1.
    InterProiIPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view]
    PfamiPF00311. PEPcase. 1 hit.
    [Graphical view]
    PRINTSiPR00150. PEPCARBXLASE.
    SUPFAMiSSF51621. SSF51621. 1 hit.
    PROSITEiPS00781. PEPCASE_1. 1 hit.
    PS00393. PEPCASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B5XKH9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIEETSKEGD GHLPLKKLES SNNQAIIAEE VALLKEMLGN ITRRMIGDDA    50
    FTVIESIMVL SEKQDYIELE KVIANISNQE MEVISRYFSI LPLLINISED 100
    VDLAYEINHQ NNTDTDYLGK LALTIKDLAG KDNGKDILEQ VNVVPVLTAH 150
    PTQVQRKTIL ELTTHIHKLL RKYRDAKAGV INLEKWRQEL YRYIEMIMQT 200
    DIIREKKLQV KNEIKNVMQY YDGSLIQAVT KLTTEYKNLA QKHGLELDNP 250
    KPITMGMWIG GDRDGNPFVT AETLCLSATV QSEVILNYYI DKLAALYRTF 300
    SLSSTLVQPN SEVERLASLS QDQSIYRGNE PYRRAFHYIQ SRLKQTQIQL 350
    TNQPAARMSS SVGLNTSAWP SPASLENPIL AYDSPVDFKA DLKAIEQSLL 400
    DNGNSALIEG DLREVMQAVD IFGFFLASID MRQDSSVQEA CVAELLKGAN 450
    IVDDYSSLSE TEKCDVLVQQ LMEEPRTLSS AAVAKSDLLE KELAIYTTAR 500
    ELKDKLGEEV IKQHIISHTE SVSDMFELAI MLKEVGLVDQ QRARVQIVPL 550
    FETIEDLDNA RDIMAAYLSH DIVKSWIATN RNYQEIMLGY SDSNKDGGYL 600
    ASGWTLYKAQ NELTAIGEEH GVKITFFHGR GGTVGRGGGP SYDAITSQPF 650
    GSIKDRIRLT EQGEIIENKY GNKDVAYYHL EMLISASINR MVTQMITDPN 700
    EIDSFREIMD SIVADSNTIY RKLVFDNPHF YDYFFEASPI KEVSSLNIGS 750
    RPAARKTITE ITGLRAIPWV FSWSQNRIMF PGWYGVGSAF KRYIDRAQGN 800
    LERLQHMYQT WPFFHSLLSN VDMVLSKSNM NIAFQYAQLA ESQDVRDVFY 850
    EILDEWQLTK NVILAIQDHD DLLEDNPSLK HSLKSRLPYF NVLNYIQIEL 900
    IKRWRNNQLD ENDEKLIHTT INGIATGLRN SG 932
    Length:932
    Mass (Da):105,903
    Last modified:November 25, 2008 - v1
    Checksum:iB4A18ACB6C7A8BB9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000829 Genomic DNA. Translation: ACI60841.1.
    RefSeqiWP_012560551.1. NC_011375.1.
    YP_002285536.1. NC_011375.1.

    Genome annotation databases

    EnsemblBacteriaiACI60841; ACI60841; Spy49_0513.
    GeneIDi6985528.
    KEGGisoz:Spy49_0513.
    PATRICi19756049. VBIStrPyo129711_0537.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000829 Genomic DNA. Translation: ACI60841.1 .
    RefSeqi WP_012560551.1. NC_011375.1.
    YP_002285536.1. NC_011375.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 471876.Spy49_0513.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACI60841 ; ACI60841 ; Spy49_0513 .
    GeneIDi 6985528.
    KEGGi soz:Spy49_0513.
    PATRICi 19756049. VBIStrPyo129711_0537.

    Phylogenomic databases

    eggNOGi COG2352.
    HOGENOMi HOG000238647.
    KOi K01595.
    OMAi ELSTISC.
    OrthoDBi EOG6TJ7T8.

    Family and domain databases

    HAMAPi MF_00595. PEPcase_type1.
    InterProi IPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view ]
    Pfami PF00311. PEPcase. 1 hit.
    [Graphical view ]
    PRINTSi PR00150. PEPCARBXLASE.
    SUPFAMi SSF51621. SSF51621. 1 hit.
    PROSITEi PS00781. PEPCASE_1. 1 hit.
    PS00393. PEPCASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of a nephritogenic and highly transformable M49 strain of Streptococcus pyogenes."
      McShan W.M., Ferretti J.J., Karasawa T., Suvorov A.N., Lin S., Qin B., Jia H., Kenton S., Najar F., Wu H., Scott J., Roe B.A., Savic D.J.
      J. Bacteriol. 190:7773-7785(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: NZ131Imported.

    Entry informationi

    Entry nameiB5XKH9_STRPZ
    AccessioniPrimary (citable) accession number: B5XKH9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 25, 2008
    Last sequence update: November 25, 2008
    Last modified: October 1, 2014
    This is version 41 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3