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B5XII0 (B5XII0_STRPZ) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
6-phospho-beta-galactosidase HAMAP MF_01574 RuleBase RU004469
EC=3.2.1.85 HAMAP MF_01574 RuleBase RU004469
Alternative name(s):
Beta-D-phosphogalactoside galactohydrolase HAMAP MF_01574
P-beta-Gal HAMAP MF_01574
Gene names
Name:lacG HAMAP MF_01574 EMBL ACI61842.1
Ordered Locus Names:Spy49_1584c
OrganismStreptococcus pyogenes serotype M49 (strain NZ131) [Complete proteome] [HAMAP]
Taxonomic identifier471876 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length477 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

A 6-phospho-beta-D-galactoside + H2O = 6-phospho-D-galactose + an alcohol. HAMAP MF_01574 RuleBase RU004469

Pathway

Carbohydrate metabolism; lactose degradation; D-galactose 6-phosphate and beta-D-glucose from lactose 6-phosphate: step 1/1. HAMAP MF_01574 RuleBase RU004469

Sequence similarities

Belongs to the glycosyl hydrolase 1 family. HAMAP MF_01574 RuleBase RU003690

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1691Proton donor By similarity HAMAP MF_01574
Active site3841Nucleophile By similarity HAMAP MF_01574

Sequences

Sequence LengthMass (Da)Tools
B5XII0 [UniParc].

Last modified November 25, 2008. Version 1.
Checksum: A2B08D898E38A27A

FASTA47754,801
        10         20         30         40         50         60 
MKDIQGETEM TKTLPKDFIF GGATAAYQAE GATHTDGKGP VAWDKYLEDN YWYTAEPASD 

        70         80         90        100        110        120 
FYNRYPVDLK LSEEFGVNGI RISIAWSRIF PTGKGEVNPK GVEYYHNLFA ECHKRGVEPF 

       130        140        150        160        170        180 
VTLHHFDTPE ALHSDGDFLN RENIEHFVNY AEFCFKEFSE VNYWTTFNEI GPIGDGQYLV 

       190        200        210        220        230        240 
GKFPPGIQYD LAKVFQSHHN MMVSHARAVK LFKDSGYSGE IGVVHALPTK YPFDANNPDD 

       250        260        270        280        290        300 
VRAAELEDII HNKFILDATY LGKYSDKTME GVNHILEVNG GELDLCEEDF VALDAAKDLN 

       310        320        330        340        350        360 
DFLGINYYMS DWMQAFDGET EIIHNGKGEK GSSKYQIKGV GRRKAPVDVP KTDWDWIIFP 

       370        380        390        400        410        420 
QGLYDQIMRV KADYPNYKKI YITENGLGYK DEFVDNTVYD DGRIDYVKKH LEVISDAISD 

       430        440        450        460        470 
GVNVKGYFMW SLMDVFSWSN GYEKRYGLFY VDFETQERYP KKSAYWYKKV AETQVIE

« Hide

References

[1]"Genome sequence of a nephritogenic and highly transformable M49 strain of Streptococcus pyogenes."
McShan W.M., Ferretti J.J., Karasawa T., Suvorov A.N., Lin S., Qin B., Jia H., Kenton S., Najar F., Wu H., Scott J., Roe B.A., Savic D.J.
J. Bacteriol. 190:7773-7785(2008) [PubMed: 18820018] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000829 Genomic DNA. Translation: ACI61842.1.
RefSeqYP_002286537.1. NC_011375.1.

3D structure databases

ProteinModelPortalB5XII0.
ModBaseSearch...

Protein-protein interaction databases

STRINGB5XII0.

Protein family/group databases

CAZyGH1. Glycoside Hydrolase Family 1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBSTRT00000050109; EBSTRP00000060150; EBSTRG00000050101.
GeneID6985114.
GenomeReviewsGene locus Spy49_1584c in contig CP000829_GR.
KEGGsoz:Spy49_1584c.
PATRIC19758291. VBIStrPyo129711_1634.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000027409.
HOGENOMHBG316462.
OMAFVNYAEF.
ProtClustDBPRK13511.

Family and domain databases

HAMAPMF_01574. LacG.
[Tree]
InterProIPR005928. 6P-beta-galactosidase.
IPR001360. Glyco_hydro_1.
IPR018120. Glyco_hydro_1_AS.
IPR013781. Glyco_hydro_subgr_catalytic.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
Gene3DG3DSA:3.20.20.80. Glyco_hydro_cat. 1 hit.
KOK01220.
PANTHERPTHR10353. Glyco_hydro_1. 1 hit.
PfamPF00232. Glyco_hydro_1. 1 hit.
[Graphical view]
PRINTSPR00131. GLHYDRLASE1.
SUPFAMSSF51445. Glyco_hydro_cat. 1 hit.
TIGRFAMsTIGR01233. LacG. 1 hit.
PROSITEPS00572. GLYCOSYL_HYDROL_F1_1. 1 hit.
PS00653. GLYCOSYL_HYDROL_F1_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB5XII0_STRPZ
AccessionPrimary (citable) accession number: B5XII0
Entry history
Integrated into UniProtKB/TrEMBL: November 25, 2008
Last sequence update: November 25, 2008
Last modified: December 14, 2011
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info