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B5WWZ9 (FAO2_LOTJA) Reviewed, UniProtKB/Swiss-Prot

Last modified September 5, 2012. Version 13. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Long-chain-alcohol oxidase FAO2
EC=1.1.3.20
Alternative name(s):
Long-chain fatty alcohol oxidase 2
Gene names
Name:FAO2
OrganismLotus japonicus (Lotus corniculatus var. japonicus)
Taxonomic identifier34305 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › fabids › Fabales › Fabaceae › Papilionoideae › Loteae › Lotus

Protein attributes

Sequence length750 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Long-chain fatty alcohol oxidase involved in the omega-oxidation pathway of lipid degradation By similarity.

Catalytic activity

A long-chain alcohol + O2 = a long-chain aldehyde + H2O2.

Subcellular location

Membrane; Multi-pass membrane protein Potential.

Sequence similarities

Belongs to the GMC oxidoreductase family.

Ontologies

Keywords
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix
   LigandFAD
Flavoprotein
   Molecular functionOxidoreductase
Gene Ontology (GO)
   Cellular_componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionflavin adenine dinucleotide binding

Inferred from electronic annotation. Source: InterPro

long-chain-alcohol oxidase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 750750Long-chain-alcohol oxidase FAO2
PRO_0000395508

Regions

Transmembrane92 – 11221Helical; Potential
Transmembrane148 – 16821Helical; Potential
Nucleotide binding239 – 25416FAD Potential

Sites

Active site6831 By similarity

Sequences

Sequence LengthMass (Da)Tools
B5WWZ9 [UniParc].

Last modified November 25, 2008. Version 1.
Checksum: F36C985DADD053A0

FASTA75082,355
        10         20         30         40         50         60 
MEREESCETH PLLKGGRRKE KGYSHGLSSS QMHVIAAICE ALFPSQPLDS QNNQSSVDKA 

        70         80         90        100        110        120 
LSAFYTASGS QAPLPDEAAE LLFKFNRSFP EALSLVSWVL LILSFRLGTL LLCGTLCLDW 

       130        140        150        160        170        180 
RWPFIHKFSE IPLEKREEIL KRWSREKCWI PLRLVFVLTK LVCFYNLFSR ADVNGHNPIW 

       190        200        210        220        230        240 
KAIGYQVDTR EKLTQKKRPL QEGLIETMYE TDSTLIQSLT EKGLEVTEDL EQNMYKIKCD 

       250        260        270        280        290        300 
AVIVGSGCGG GVAAAVLANS GHKVIILEKG EYFVSHDYSS LEGPSMNELY ESGGILPSLD 

       310        320        330        340        350        360 
GKMMILAGST LGGXSAINWS ACIRTPDSVL REWSEKHKIP LFASPDYQSA MDTVCRRIGV 

       370        380        390        400        410        420 
TENCNKESFQ NQILRQGCAK IGFKVEPVAI NSSADHYCGS CCYGCRTGDK KGTESTWLVD 

       430        440        450        460        470        480 
AVGNGAVILT GCKAEKLNFT LKDGDNGTKR KTCSGVIASA TWRSKVTKKL QIESKVTISA 

       490        500        510        520        530        540 
CGSLSTPPLM ISSGLKNPNI GKNLHLHPCQ FAWGYFPEDM TNFSGNNYEG GIITSIHKVF 

       550        560        570        580        590        600 
EEDSTSTPRI IIEAPALGPG SFSALVPWVS GLDVKERMVK YARTANLFAL VRDHGSGEVK 

       610        620        630        640        650        660 
AEGRISYKLD KIDRESLQTG LRKALRILVA AGAVEVGTYR SDGQRIKCRG IKESDLEEFL 

       670        680        690        700        710        720 
DSVRVVGGPS SRNEVWTVFT SAHQMTSCRM SATEEEGAVD ENGESWEAKG LYVCDGSVLP 

       730        740        750 
SAVGVNPMIT IQSTAYCIAS NIAESLKKQN

« Hide

References

[1]"Cloning and characterization of long chain fatty alcohol oxidase LjFAO2 in Lotus japonicus."
Zhao S., Lin Z., Luo D., Ma W., Cheng Q.
Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM900800 mRNA. Translation: CAP15763.1.
UniGeneLja.3526.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR012400. ADH_lc_FA.
IPR000172. GMC_OxRdtase_N.
IPR007867. GMC_OxRtase_C.
[Graphical view]
PfamPF05199. GMC_oxred_C. 1 hit.
PF00732. GMC_oxred_N. 1 hit.
[Graphical view]
PIRSFPIRSF028937. Lg_Ch_AO. 1 hit.
PROSITEPS00623. GMC_OXRED_1. False negative.
PS00624. GMC_OXRED_2. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameFAO2_LOTJA
AccessionPrimary (citable) accession number: B5WWZ9
Entry history
Integrated into UniProtKB/Swiss-Prot: July 13, 2010
Last sequence update: November 25, 2008
Last modified: September 5, 2012
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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