B5US37 (B5US37_BACCE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aspartate carbamoyltransferase HAMAP MF_00001
EC=2.1.3.2 HAMAP MF_00001

Alternative name(s):
Aspartate transcarbamylase HAMAP MF_00001

Gene names

Name:	pyrB HAMAP MF_00001 EMBL EDZ51145.1
ORF Names:	BCAH1134_3963 EMBL EDZ51145.1

Organism

Bacillus cereus AH1134 EMBL EDZ51145.1

Taxonomic identifier

405533 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	304 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate. HAMAP MF_00001
Pathway	Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3. HAMAP MF_00001
Sequence similarities	Belongs to the ATCase/OTCase family. HAMAP MF_00001 RuleBase RU003634

Ontologies

Keywords
Biological process	Pyrimidine biosynthesis HAMAP MF_00001
Molecular function	Transferase HAMAP MF_00001 RuleBase RU003634 EMBL EDZ51145.1
Gene Ontology (GO)
Biological process	'de novo' pyrimidine base biosynthetic process Inferred from electronic annotation. Source: InterPro cellular amino acid metabolic process Inferred from electronic annotation. Source: InterPro pyrimidine nucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	amino acid binding Inferred from electronic annotation. Source: InterPro aspartate carbamoyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B5US37 [UniParc]. Last modified November 25, 2008. Version 1. Checksum: 7E4FE09447EE773E	FASTA	304	34,722
	10 20 30 40 50 60 MSHLLTMSEL SEVEISEILK DAEDFANGKE SKTTEQTFVA NLFFENSTRT RFSFEVAEKR 70 80 90 100 110 120 LGLDVLNFSA DASSVQKGET LYDTIRTLES IGTKAVVIRH EQDRYFDELK DQVNIPILNA 130 140 150 160 170 180 GDGCGNHPTQ CLLDLLTIKQ EFGRFEGLKI AIVGDVRHSR VARSNAEALT KLGATIYFAS 190 200 210 220 230 240 PEEWKDEDNT FGTYKPLDEL VPEVDVMMLL RVQHERHDHY ETDIMKEYHE KHGLTVEREK 250 260 270 280 290 300 RMKEGSIIMH PAPVNRDVEI ASELVECERS RIFKQMENGV YVRMAVLKRA LPNVLGGMKH ELFV

References

[1]	"Genome sequence of Bacillus cereus AH1134." Dodson R.J., Durkin A.S., Rosovitz M.J., Rasko D.A., Callegan M.C., Kolsto A.B., Okstad O.A., Ravel J., Sutton G. Submitted (SEP-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: AH1134 EMBL EDZ51145.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	ABDA02000006 Genomic DNA. Translation: EDZ51145.1.
3D structure databases
ProteinModelPortal	B5US37.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
PATRIC	24780029. VBIBacCer51833_3576.
Family and domain databases
HAMAP	MF_00001. Asp_carb_tr. [Tree]
InterPro	IPR006132. Asp/Orn_carbamoyltranf_P-bd. IPR006130. Asp/Orn_carbamoylTrfase. IPR006131. Asp_carbamoyltransf_Asp/Orn-bd. IPR002082. Asp_carbamoyltransf_euk. [Graphical view]
Pfam	PF00185. OTCace. 1 hit. PF02729. OTCace_N. 1 hit. [Graphical view]
PRINTS	PR00100. AOTCASE. PR00101. ATCASE.
SUPFAM	SSF53671. Asp/Orn_carbamoyltranf. 1 hit.
TIGRFAMs	TIGR00670. Asp_carb_tr. 1 hit.
PROSITE	PS00097. CARBAMOYLTRANSFERASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B5US37_BACCE

Accession

Primary (citable) accession number: B5US37

Entry history

Integrated into UniProtKB/TrEMBL:	November 25, 2008
Last sequence update:	November 25, 2008
Last modified:	December 14, 2011
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)