B5UMX6 (B5UMX6_BACCE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Adenine phosphoribosyltransferase HAMAP MF_00004
Short name=APRT HAMAP MF_00004
EC=2.4.2.7 HAMAP MF_00004

Gene names

Name:	apt HAMAP MF_00004 EMBL EDZ52366.1
ORF Names:	BCAH1134_4510 EMBL EDZ52366.1

Organism

Bacillus cereus AH1134 EMBL EDZ52366.1

Taxonomic identifier

405533 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	170 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis By similarity. HAMAP MF_00004
Catalytic activity	AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate. HAMAP MF_00004
Pathway	Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenine: step 1/1. HAMAP MF_00004
Subunit structure	Homodimer By similarity. HAMAP MF_00004
Subcellular location	Cytoplasm By similarity HAMAP MF_00004.
Sequence similarities	Belongs to the purine/pyrimidine phosphoribosyltransferase family. HAMAP MF_00004

Ontologies

Keywords
Biological process	Purine salvage HAMAP MF_00004
Cellular component	Cytoplasm HAMAP MF_00004
Molecular function	Glycosyltransferase HAMAP MF_00004 EMBL EDZ52366.1 Transferase
Gene Ontology (GO)
Biological process	adenine salvage Inferred from electronic annotation. Source: HAMAP purine ribonucleoside salvage Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	adenine phosphoribosyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B5UMX6 [UniParc]. Last modified November 25, 2008. Version 1. Checksum: A491A98F47D58FF7	FASTA	170	18,630
	10 20 30 40 50 60 MDFKQHIAIV PDYPKEGIVF KDITPLMNDG KAYKAATDAI VEYAKERDID VVVGPEARGF 70 80 90 100 110 120 IIGCPVSYAL EVGFAPVRKL GKLPREVITV DYGKEYGKDV LTIHKDAIKP GQRVLITDDL 130 140 150 160 170 LATGGTIEAT IKLVEELGGV VAGIAFLVEL TYLDGRKMLD GYDVLVLEKY

References

[1]	"Genome sequence of Bacillus cereus AH1134." Dodson R.J., Durkin A.S., Rosovitz M.J., Rasko D.A., Callegan M.C., Kolsto A.B., Okstad O.A., Ravel J., Sutton G. Submitted (SEP-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: AH1134 EMBL EDZ52366.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	ABDA02000003 Genomic DNA. Translation: EDZ52366.1.
3D structure databases
ProteinModelPortal	B5UMX6.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
PATRIC	24776911. VBIBacCer51833_2052.
Family and domain databases
HAMAP	MF_00004. Aden_phosphoribosyltr. [Tree]
InterPro	IPR005764. Ade_phspho_trans. IPR000836. PRibTrfase. [Graphical view]
Pfam	PF00156. Pribosyltran. 1 hit. [Graphical view]
TIGRFAMs	TIGR01090. Apt. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B5UMX6_BACCE

Accession

Primary (citable) accession number: B5UMX6

Entry history

Integrated into UniProtKB/TrEMBL:	November 25, 2008
Last sequence update:	November 25, 2008
Last modified:	December 14, 2011
This is version 14 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)