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Protein
Submitted name:

Sucrase-isomaltase

Gene

Sis

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidaseImported, Hydrolase

Protein family/group databases

CAZyiGH31 Glycoside Hydrolase Family 31

Names & Taxonomyi

Protein namesi
Submitted name:
Sucrase-isomaltaseImported (EC:3.2.1.10Imported)
Gene namesi
Name:SisImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1917233 Sis

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 32HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Chemistry databases

ChEMBLiCHEMBL1667666

PTM / Processingi

Proteomic databases

PeptideAtlasiB5THE3
PRIDEiB5THE3

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini51 – 100P-typeInterPro annotationAdd BLAST50
Domaini922 – 969P-typeInterPro annotationAdd BLAST48

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1065 Eukaryota
COG1501 LUCA
HOGENOMiHOG000067936
HOVERGENiHBG080721

Family and domain databases

CDDicd00111 Trefoil, 2 hits
Gene3Di2.60.40.1180, 4 hits
InterProiView protein in InterPro
IPR031727 Gal_mutarotase_N
IPR011013 Gal_mutarotase_sf_dom
IPR000322 Glyco_hydro_31
IPR030458 Glyco_hydro_31_AS
IPR030459 Glyco_hydro_31_CS
IPR025887 Glyco_hydro_31_N_dom
IPR013780 Glyco_hydro_b
IPR017853 Glycoside_hydrolase_SF
IPR017957 P_trefoil_CS
IPR000519 P_trefoil_dom
PfamiView protein in Pfam
PF13802 Gal_mutarotas_2, 1 hit
PF01055 Glyco_hydro_31, 2 hits
PF16863 NtCtMGAM_N, 2 hits
PF00088 Trefoil, 2 hits
SMARTiView protein in SMART
SM00018 PD, 2 hits
SUPFAMiSSF51445 SSF51445, 4 hits
SSF74650 SSF74650, 2 hits
PROSITEiView protein in PROSITE
PS00129 GLYCOSYL_HYDROL_F31_1, 2 hits
PS00707 GLYCOSYL_HYDROL_F31_2, 2 hits
PS00025 P_TREFOIL_1, 1 hit
PS51448 P_TREFOIL_2, 2 hits

Sequencei

Sequence statusi: Complete.

B5THE3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKKKFSGLE ISLIVLFIIV TIIAIALVVV LATKVPAVEE VKSPTSTPSP
60 70 80 90 100
GRCPPEQGEP LNERINCIPE QHPTKAKCEE RGCCWRPWNN TIIPWCFFAD
110 120 130 140 150
NHGYTAASVT NDNSGLKATL SRIPSPTLFG EDIKSVLLTT QSQTRNRFRF
160 170 180 190 200
KLTDPNNKRY EVPHQFVKDG NGIPAADTLY DVKVSENPFS IKVIRKSNNK
210 220 230 240 250
VLFDTSIGPL VYSNQYLQIS TRLPSEYIYG FGEHIHKRFR HDLYWKTWPI
260 270 280 290 300
FTRDEIPGDN NHNLYGHQTF FMGIEDNSGK SYGVFLMNSN AMEVFIQPTP
310 320 330 340 350
IITYRVTGGV LDFYIFLGDT PEQVVQQYQE LIGRPAMPAY WNLGFQLSRW
360 370 380 390 400
NYVSLDKVKE VVRRNREAGI PYDAQVTDID YMEDKKDFTY DEVAFKGLPE
410 420 430 440 450
FAQDLHNHGQ KYIIILDPAI SINKRANGAE YQTYVRGNEQ NVWVKESDGT
460 470 480 490 500
TSLIGEVWPG LTVYPDFTNP RTWEWWANEC NLFHQQVEYD GLWIDMNEVS
510 520 530 540 550
SFIHGSQKGC APNLLNYPPF TPGILDKIMY SKTLCMDAVQ HWGNQYDVHS
560 570 580 590 600
LYGYSMAIAT EKAVEKVFPN KRSFILTRST FAGSGHHAAH WLGDNTASWE
610 620 630 640 650
QMEWSITGML EFGMFGMPLV GADICGFLAN TTEELCRRWM QLGAFYPFSR
660 670 680 690 700
NHNAEGYAEQ DPAFWGADSL LVNTSRHYLT IRYTLLPFLY TLFYRAHAFG
710 720 730 740 750
ETVARPFLHE FYEDPNSWIE DTQFLWGPAL LITPVLRPET KYVSAYIPDA
760 770 780 790 800
TWYDYETGEK RPWRKQRVDM YLPEDKIGLH LRGGYIIPTQ QPDVTTTASR
810 820 830 840 850
KNPLGLIVAL DENQAAKGEL FWDDGESKDT IEKKIYILYE FSVSNNNLIV
860 870 880 890 900
NCTHSSYPEG NTLVFKTIKV LGLSATVTAV TVGENDQQMN PHLAFTFDAF
910 920 930 940 950
NKILSITDLT FNLGKTFIVR WTTQSFSDNE KFTCYPDVGT ATEKTCVERG
960 970 980 990 1000
CIWEPVSGLA NVPPCYFPSN HNPYLLTSTQ KLATGITAEL QLNPASARIK
1010 1020 1030 1040 1050
LPSNPISTLR VEVKYHKNDM LQFKIYDAHH KRYEVPVPLN IPDTPTSSEE
1060 1070 1080 1090 1100
NRLYDVEIKE NPFGIQVRRR STGKLIWDSC LPGFAFNDQF IQISTRLPSQ
1110 1120 1130 1140 1150
YLYGFGEAEH TAFKRNLNWH TWGMFTRDQP PGYKLNSYGF HPYYMALEDE
1160 1170 1180 1190 1200
GNAHGVLLQN SNGMDVTFQP TPALTYRTIG GILDFYMFLG PTPEGATKQY
1210 1220 1230 1240 1250
HEVIGFPVMP PYWALGFQLC RYGYRNTSEI EQLYNDMKAA QIPYDVQYTD
1260 1270 1280 1290 1300
INYMERQLDF TIGERFKTLP QFVEKIRKEG MKYIVILDPA ISGNETQPYP
1310 1320 1330 1340 1350
AFERGIQKDV FVKWPNTNDI CWAKVWPDLP NITIDETITE DEAVNASRAH
1360 1370 1380 1390 1400
VAFPDFFRNS TSEWWTREIY DFYNEKMKFD GLWIDMNEPS SFVNGTVTNK
1410 1420 1430 1440 1450
CRNDTLNYPP YFPELTKRNE GLHFRTMCME TEHILSDGSS VLHYDVHNLY
1460 1470 1480 1490 1500
GWSQVKPTLD ALRNTTGLRG IVISRSTYPT AGRWGGHWLG DNYANWENLE
1510 1520 1530 1540 1550
KSLIGMLEFN LFGIPYVGAD ICGFFNDSEY HLCARWMQVG AFYPYSRNHN
1560 1570 1580 1590 1600
IQFTRRQDPV SWNETFAQMS KKVLEIRYTL LPYFYTQMHE AHIHGGTVIR
1610 1620 1630 1640 1650
PLMHEFFDDK ETWEIYKQFL WGPAFMVTPV IGPFQTAVNG YVPKARWFDY
1660 1670 1680 1690 1700
HTGEDIKVRG KLQTFSAPFD TINLHVRGGY ILPCQEPAQN TYYSRQNYMK
1710 1720 1730 1740 1750
LIVAADDNQT AKGSLFWDDG ESIDTYEKNQ YTLIEFNLNQ KTLTSTVLKN
1760 1770 1780 1790 1800
GYRNKSEMKL GNIYVWGKGT THINQVNLTY GGNEQQLLFT QDEAKEILTI
1810
ELKNVNVTLD EPIQISWS
Length:1,818
Mass (Da):209,100
Last modified:November 4, 2008 - v1
Checksum:i4ADC2AB3DBE4A2B9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EU937530 mRNA Translation: ACH86012.1
UniGeneiMm.261054

Similar proteinsi

Entry informationi

Entry nameiB5THE3_MOUSE
AccessioniPrimary (citable) accession number: B5THE3
Entry historyiIntegrated into UniProtKB/TrEMBL: November 4, 2008
Last sequence update: November 4, 2008
Last modified: May 23, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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