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B5THE2

- B5THE2_MOUSE

UniProt

B5THE2 - B5THE2_MOUSE

Protein
Submitted name:

Maltase-glucoamylase

Gene

Mgam

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 35 (01 Oct 2014)
      Sequence version 1 (04 Nov 2008)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. alpha-1,4-glucosidase activity Source: MGI
    2. amylase activity Source: MGI
    3. carbohydrate binding Source: InterPro
    4. maltose alpha-glucosidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. carbohydrate metabolic process Source: InterPro

    Keywords - Molecular functioni

    GlycosidaseUniRule annotationImported, Hydrolase

    Enzyme and pathway databases

    ReactomeiREACT_217960. Digestion of dietary carbohydrate.

    Protein family/group databases

    CAZyiGH31. Glycoside Hydrolase Family 31.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Maltase-glucoamylaseImported (EC:3.2.1.20Imported)
    Submitted name:
    Protein MgamImported
    Gene namesi
    Name:MgamImported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 6

    Organism-specific databases

    MGIiMGI:1203495. Mgam.

    Expressioni

    Gene expression databases

    GenevestigatoriB5THE2.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyl hydrolase 31 family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1501.
    GeneTreeiENSGT00740000115152.
    HOVERGENiHBG080721.
    KOiK12047.
    OMAiYQTANRF.
    OrthoDBiEOG7FJGZS.
    TreeFamiTF314577.

    Family and domain databases

    Gene3Di4.10.110.10. 2 hits.
    InterProiIPR011013. Gal_mutarotase_SF_dom.
    IPR000322. Glyco_hydro_31.
    IPR017853. Glycoside_hydrolase_SF.
    IPR000519. P_trefoil.
    [Graphical view]
    PfamiPF01055. Glyco_hydro_31. 2 hits.
    PF00088. Trefoil. 2 hits.
    [Graphical view]
    SMARTiSM00018. PD. 2 hits.
    [Graphical view]
    SUPFAMiSSF51445. SSF51445. 4 hits.
    SSF57492. SSF57492. 1 hit.
    SSF74650. SSF74650. 2 hits.
    PROSITEiPS00129. GLYCOSYL_HYDROL_F31_1. 2 hits.
    PS00707. GLYCOSYL_HYDROL_F31_2. 1 hit.
    PS51448. P_TREFOIL_2. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B5THE2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAGRRFKKFS KLELVLIVLL LVLFIIAVVL IVLLANSTPE NAIGAETTGT     50
    PDTTVTRTTL NSPNCPVLSE LERINCIPDQ SSNKGTCDER GCCWDPQGSI 100
    SVPCYYSRNH GYKMESDVVN TNAGFTATLK NLPSAPVFGN SIENILLTAE 150
    YQTSNRFHFK LTDQTKKRYE VPHEHVQPFS GNAPSSLNYK VEVSKEPFSI 200
    KVTRKSNNRV LFDSSIGPLL FSDQFLQFST HLPSANVYGL GEHVHQQYRH 250
    NMNWKTWPMF SRDTTPNEDG TNLYGVQTFF LCLEDNSGLS FGVFLMNSNA 300
    MEVTLQPTPA ITYRTTGGIL DFYVFLGNTP EQVVQEYLEL IGRPALPSYW 350
    TLGFQLSRYD YKSLDNMKAV VERNRAAQLP YDVQHADIDY MDQKKDFTYD 400
    PVNFKGFPEF VKELHNNGQK LVIILDPAIS NNSFSSNPYG PYDRGSAMKI 450
    WVNSSDGISP VIGKVWPGTT VFPDYTSPNC AVWWTKEFEL FHKEVEFDGI 500
    WIDMNEVSNF IDGSFSGCSQ NNLNYPPFTP KVLDGYLFSK TLCMDAVQHW 550
    GKQYDVHNLY GYSMAIATAK AVKDVFPDKR SFIITRSTFA GSGKFAAHWL 600
    GDNTATWKDL QWSIPGMLEF NLFGIPMVGA DICGFAQDTY EELCRRWMQL 650
    GAFYPFSRNH NGQGYKDQDP ASFGNNSLLL NSSRHYLNIR YTLLPYLYTL 700
    FYRAHSRGDT VARPLLHEFY DDNNTWGIDR QFLWGPGLLI TPVLDQGAEK 750
    VKAYVPNATW YDYETGEELG WRKQSIEMQL PGDKIGLHLR GGYIFPTQQP 800
    ATTTEASRKN PLGLIVALDE NKEARGELFW DDGESKDTVA QNIYLFSEFS 850
    VTQNHLDVTI SSPNYKDPNN LEFQEIKIFG TREFRNVRVK QNGNLLQMSP 900
    QVTYNPNLKV ATITNIHLRL GEAYTVEWDF FTREEERIDC YPDEHGASEA 950
    NCSARGCIWE ASNTTRGPPC YFAHELYSVS NVQYDSHGAT ADISLKASTY 1000
    SNAFPSTPVN KLKLQVTYHK NEMLQFKIYD PNHSRYEVPV PLNIPSAPLS 1050
    TPEGRLYDVL IKENPFGIQI RRKTTGTVIW DSQLLGFTFN DMFIRISTRL 1100
    PSTYIYGFGE TEHTTFKIDM NWHTWGMFSR DEPPGYKKNS YGVHPYYMGL 1150
    EEDGNAHGVL LMNSNAMDVT FQPMPALTYR TIGGILDFYV FLGPTPEIVT 1200
    QQYTELIGRP VMVPYWSLGF QLCRYGYEND TEIANLYDEM VAKQIPYDVQ 1250
    YSDIDYMERQ LDFKLSPKFS GFPALINRMK ANGMRVILIL DPAISGNETE 1300
    PYPAFTRGVE NDVFIRYPNN GSIVWGKVWP DYPNITVDPS LGWDHQVEQY 1350
    RAYVAFPDFF RNSTATWWKK EIKELHSNTQ DPAKSLKFDG LWIDMNEPSS 1400
    FVNGAVPSGC SDATLNHPPY MPYLEARDRG LSSKTLCMES EQILPDGSRV 1450
    RHYDVHNLYG WSQTRPTYEA VQEVTGERGI VITRSTFPSS GRWGGHWLGD 1500
    NTAAWDQLGK SIIGMMDFSL FGISYTGSDI CGFFQDAEYE MCVRWMQLGA 1550
    FYPFSRNHNT IGTRRQDPVS WNKTFEDISR SVLETRYTLL PYLYTLMYKA 1600
    HTEGSTVVRP LLHEFVSDRE TWNIDKQFLL GPAFLVSPVL EPNARKVEAY 1650
    FPRARWYDYY KGVDINATGE WKTLEAPLEY INLHIRGGYI LPWQEPAMNT 1700
    HLSRQKFMGL RAALNAEGRA EGWLFWDDGK RINTDQYYLA RFSVNQTTLL 1750
    THEKFNNYLT GTAPLYLGYI DIWGLSSSSI TNVSISWNTN NEEVFANYNS 1800
    TTKILSVNMT DKKISLHTFN SLTWSSS 1827
    Length:1,827
    Mass (Da):208,549
    Last modified:November 4, 2008 - v1
    Checksum:i00FD29494C846ACE
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC153378 Genomic DNA. No translation available.
    AC158685 Genomic DNA. No translation available.
    EU937529 mRNA. Translation: ACH86011.1.
    RefSeqiNP_001164474.1. NM_001171003.1.
    UniGeneiMm.33401.

    Genome annotation databases

    EnsembliENSMUST00000071535; ENSMUSP00000071466; ENSMUSG00000068587.
    GeneIDi232714.
    KEGGimmu:232714.
    UCSCiuc009bnf.2. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC153378 Genomic DNA. No translation available.
    AC158685 Genomic DNA. No translation available.
    EU937529 mRNA. Translation: ACH86011.1 .
    RefSeqi NP_001164474.1. NM_001171003.1.
    UniGenei Mm.33401.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    CAZyi GH31. Glycoside Hydrolase Family 31.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000071535 ; ENSMUSP00000071466 ; ENSMUSG00000068587 .
    GeneIDi 232714.
    KEGGi mmu:232714.
    UCSCi uc009bnf.2. mouse.

    Organism-specific databases

    CTDi 8972.
    MGIi MGI:1203495. Mgam.

    Phylogenomic databases

    eggNOGi COG1501.
    GeneTreei ENSGT00740000115152.
    HOVERGENi HBG080721.
    KOi K12047.
    OMAi YQTANRF.
    OrthoDBi EOG7FJGZS.
    TreeFami TF314577.

    Enzyme and pathway databases

    Reactomei REACT_217960. Digestion of dietary carbohydrate.

    Miscellaneous databases

    NextBioi 381201.
    PROi B5THE2.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori B5THE2.

    Family and domain databases

    Gene3Di 4.10.110.10. 2 hits.
    InterProi IPR011013. Gal_mutarotase_SF_dom.
    IPR000322. Glyco_hydro_31.
    IPR017853. Glycoside_hydrolase_SF.
    IPR000519. P_trefoil.
    [Graphical view ]
    Pfami PF01055. Glyco_hydro_31. 2 hits.
    PF00088. Trefoil. 2 hits.
    [Graphical view ]
    SMARTi SM00018. PD. 2 hits.
    [Graphical view ]
    SUPFAMi SSF51445. SSF51445. 4 hits.
    SSF57492. SSF57492. 1 hit.
    SSF74650. SSF74650. 2 hits.
    PROSITEi PS00129. GLYCOSYL_HYDROL_F31_1. 2 hits.
    PS00707. GLYCOSYL_HYDROL_F31_2. 1 hit.
    PS51448. P_TREFOIL_2. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Mouse intestinal maltase-glucoamylase."
      Nichols B.L.Jr., Avery S.E., Quezada-Calvillo R., Sen P.
      Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: 129/SvImported.
      Tissue: Small intestineImported.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    3. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiB5THE2_MOUSE
    AccessioniPrimary (citable) accession number: B5THE2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 4, 2008
    Last sequence update: November 4, 2008
    Last modified: October 1, 2014
    This is version 35 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3