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Protein

Methionyl-tRNA formyltransferase

Gene

fmt

Organism
Borrelia recurrentis (strain A1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.UniRule annotation

Catalytic activityi

10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = tetrahydrofolate + N-formylmethionyl-tRNA(fMet).UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionTransferase
Biological processProtein biosynthesis

Enzyme and pathway databases

BioCyciBREC412418:G1GBI-77-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Methionyl-tRNA formyltransferaseUniRule annotation (EC:2.1.2.9UniRule annotation)
Gene namesi
Name:fmtUniRule annotation
Ordered Locus Names:BRE_67
OrganismiBorrelia recurrentis (strain A1)
Taxonomic identifieri412418 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesBorreliaceaeBorrelia
Proteomesi
  • UP000000612 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000983811 – 309Methionyl-tRNA formyltransferaseAdd BLAST309

Structurei

3D structure databases

ProteinModelPortaliB5RQP3
SMRiB5RQP3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni107 – 110Tetrahydrofolate (THF) bindingUniRule annotation4

Sequence similaritiesi

Belongs to the Fmt family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000261177
KOiK00604
OMAiLRIVFMG
OrthoDBiPOG091H01YM

Family and domain databases

Gene3Di3.10.25.10, 1 hit
HAMAPiMF_00182 Formyl_trans, 1 hit
InterProiView protein in InterPro
IPR005794 Fmt
IPR005793 Formyl_trans_C
IPR037022 Formyl_trans_C_sf
IPR002376 Formyl_transf_N
IPR036477 Formyl_transf_N_sf
IPR011034 Formyl_transferase-like_C_sf
PfamiView protein in Pfam
PF02911 Formyl_trans_C, 1 hit
PF00551 Formyl_trans_N, 1 hit
SUPFAMiSSF50486 SSF50486, 1 hit
SSF53328 SSF53328, 1 hit
TIGRFAMsiTIGR00460 fmt, 1 hit

Sequencei

Sequence statusi: Complete.

B5RQP3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRIFFASSDG IALEVLKKIS DQYDVVGVLT APDKPSGRGL SLKVNDIKRE
60 70 80 90 100
ALSRKITVLQ PVVLDADVIN LVKSLEPELM LVFSYGKIFK QEFLDIFPVG
110 120 130 140 150
CINIHPSLLP KYRGPSPIQT VILNGDSVSG ITVQKMTLEM DSGNILAQSQ
160 170 180 190 200
FEIKSFNTSV DIFEYVSLNS FDLVIEALNK LLKGDIGIVQ DKNNATYCSF
210 220 230 240 250
LGKEHRTIDF KLSAFDIKNK INAYNPWPLA RARLDNNEII FYRADFISTN
260 270 280 290 300
DYDDQVIGKI IAFDPSKGLL VKTGDGILVV LELQRIGKKV LDCVSFYHGN

RDLIGKVFS
Length:309
Mass (Da):34,473
Last modified:November 4, 2008 - v1
Checksum:iC513BA8427FC43AF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000993 Genomic DNA Translation: ACH94327.1
RefSeqiWP_012538632.1, NC_011244.1

Genome annotation databases

EnsemblBacteriaiACH94327; ACH94327; BRE_67
KEGGibre:BRE_67

Similar proteinsi

Entry informationi

Entry nameiFMT_BORRA
AccessioniPrimary (citable) accession number: B5RQP3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: November 4, 2008
Last modified: March 28, 2018
This is version 65 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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