B5RQA5 (GCP_BORRA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	BRE_776

Organism

Borrelia recurrentis (strain A1) [Complete proteome] [HAMAP]

Taxonomic identifier

412418 [NCBI]

Taxonomic lineage

Bacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Borrelia

Protein attributes

Sequence length	338 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 338	338	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_1000145952

Sequences

	Sequence		Length	Mass (Da)
	B5RQA5 [UniParc]. Last modified November 4, 2008. Version 1. Checksum: 518F8FF10D97514C	FASTA	338	37,496
	10 20 30 40 50 60 MKVLGIESSC DDCCAAIVEN GNTILSNIKL SQKEHKKYYG IVPEIASRLH TEFIMYVCQQ 70 80 90 100 110 120 AIISAKINIS EIDLIAVTSQ PGLIGSLIVG VNFAKGLSIA LKKPLICIDH ILGHLYAPLL 130 140 150 160 170 180 NHTIEYPFLS LVLSGGHTIL AKQNNFDDIE ILGRTLDDAC GEAFDKIAKH YKMGFPGGPN 190 200 210 220 230 240 IEKLAIDGNQ YAFNFPITIF DKKENRYDFS YSGLKTACIH QLEKFKNNNA QITNNNIAAS 250 260 270 280 290 300 FQRAAFENLI IPIKRAIKDT NIKKLIISGG VASNLYLREK IKNLEIETYY PPIDLCTDNA 310 320 330 AMIAGIGYLM YLKYGASSIE TNANSRIENY KYTKGVKL

References

[1]

"The genome of Borrelia recurrentis, the agent of deadly louse-borne relapsing fever, is a degraded subset of tick-borne Borrelia duttonii." Lescot M., Audic S., Robert C., Nguyen T.T., Blanc G., Cutler S.J., Wincker P., Couloux A., Claverie J.-M., Raoult D., Drancourt M. PLoS Genet. 4:E1000185-E1000185(2008) [PubMed: 18787695] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: A1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000993 Genomic DNA. Translation: ACH94989.1.
RefSeq	YP_002223210.1. NC_011244.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B5RQA5.
Protein family/group databases
MEROPS	M22.001.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBORT00000005771; EBBORP00000005346; EBBORG00000005771.
GeneID	6919318.
GenomeReviews	Gene locus BRE_776 in contig CP000993_GR.
KEGG	bre:BRE_776.
PATRIC	20570723. VBIBorRec40566_0781.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000006822.
HOGENOM	HBG304663.
OMA	PAVGVHH.
ProtClustDB	PRK09604.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017860. Peptidase_M22_CS. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_BORRA

Accession

Primary (citable) accession number: B5RQA5

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	November 4, 2008
Last modified:	January 25, 2012
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program