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B5RPW7 (ACKA_BORRA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetate kinase
EC=2.7.2.1
Alternative name(s):
Acetokinase
Gene names
Name:ackA
Ordered Locus Names:BRE_629
OrganismBorrelia recurrentis (strain A1) [Complete proteome] [HAMAP]
Taxonomic identifier412418 [NCBI]
Taxonomic lineageBacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Borrelia

Protein attributes

Sequence length408 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020

ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020

Subcellular location

Cytoplasm By similarity HAMAP MF_00020.

Sequence similarities

Belongs to the acetokinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processorganic acid metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

acetate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 408408Acetate kinase HAMAP MF_00020
PRO_1000089962

Sequences

Sequence LengthMass (Da)Tools
B5RPW7 [UniParc].

Last modified November 4, 2008. Version 1.
Checksum: C7ABF008FA4E5A4E

FASTA40846,394
        10         20         30         40         50         60 
MKNIIILIIN TGSSSLKFTL YEYQYQSEQI LASGIIEKIK TTQAIIKIKF KNKLLELTNL 

        70         80         90        100        110        120 
NIKSHKKALK HLIKTLTNKK TKIINYLDQI QGIGHRIVHG GAQFKNSVII NQNVLNELKK 

       130        140        150        160        170        180 
ISHLAPLHNP IAIKVIEQMF ILFPNAKQVA CFDTSWHQTM NQKAFLYATP YSWYKDYHIR 

       190        200        210        220        230        240 
KYGFHGLSYA YITKRTAIIL NKNIEDLNLI ILHLGNGASI NAVQKGRSYD TSMGLTPLEG 

       250        260        270        280        290        300 
LVMGTRSGDI DPTIIPLMSK ILKKTTKQIE NILNKESGML GISCKSNDLR DIWIESNNNE 

       310        320        330        340        350        360 
YNSKLAVEIM TYRIKKYIGS YLAALDFNID AIIFTAGIGT SDYEIRKLSL QGFEKIGIKI 

       370        380        390        400 
DFQKNNLAID KNTEYDISSN QSNIKILVIP TNEELTILED TYDLIKNN

« Hide

References

[1]"The genome of Borrelia recurrentis, the agent of deadly louse-borne relapsing fever, is a degraded subset of tick-borne Borrelia duttonii."
Lescot M., Audic S., Robert C., Nguyen T.T., Blanc G., Cutler S.J., Wincker P., Couloux A., Claverie J.-M., Raoult D., Drancourt M.
PLoS Genet. 4:E1000185-E1000185(2008) [PubMed: 18787695] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: A1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000993 Genomic DNA. Translation: ACH94851.1.
RefSeqYP_002223072.1. NC_011244.1.

3D structure databases

ProteinModelPortalB5RPW7.
ModBaseSearch...

Protein-protein interaction databases

STRINGB5RPW7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBORT00000005570; EBBORP00000005145; EBBORG00000005570.
GeneID6919171.
GenomeReviewsGene locus BRE_629 in contig CP000993_GR.
KEGGbre:BRE_629.
PATRIC20570421. VBIBorRec40566_0638.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000007562.
HOGENOMHBG285863.
OMADEGHEGA.
ProtClustDBPRK00180.

Family and domain databases

HAMAPMF_00020. Acetate_kinase.
[Tree]
InterProIPR004372. Ac/Proprionate_kinase.
IPR000890. Aliphatic_acid_kin_short-chain.
IPR023865. Aliphatic_acid_kinase_CS.
[Graphical view]
KOK00925.
PANTHERPTHR21060. Acetate_kin. 1 hit.
PfamPF00871. Acetate_kinase. 1 hit.
[Graphical view]
PIRSFPIRSF000722. Acetate_prop_kin. 1 hit.
PRINTSPR00471. ACETATEKNASE.
TIGRFAMsTIGR00016. AckA. 1 hit.
PROSITEPS01075. ACETATE_KINASE_1. 1 hit.
PS01076. ACETATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameACKA_BORRA
AccessionPrimary (citable) accession number: B5RPW7
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: November 4, 2008
Last modified: January 25, 2012
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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