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B5RMX9 (PTH_BORDL) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Peptidyl-tRNA hydrolase

Short name=PTH
EC=3.1.1.29
Gene names
Name:pth
Ordered Locus Names:BDU_793
OrganismBorrelia duttonii (strain Ly) [Complete proteome] [HAMAP]
Taxonomic identifier412419 [NCBI]
Taxonomic lineageBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeBorrelia

Protein attributes

Sequence length188 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis By similarity. HAMAP-Rule MF_00083

Catalytic activity

N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA. HAMAP-Rule MF_00083

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00083

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00083.

Sequence similarities

Belongs to the PTH family.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionaminoacyl-tRNA hydrolase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 188188Peptidyl-tRNA hydrolase HAMAP-Rule MF_00083
PRO_1000092911

Sequences

Sequence LengthMass (Da)Tools
B5RMX9 [UniParc].

Last modified November 4, 2008. Version 1.
Checksum: AE79B567EEC62D5A

FASTA18821,062
        10         20         30         40         50         60 
MNLLIVGLGN PGSNFLHTRH NVGFGLIDKL VMKNALSLRK AKNYEYADFN IDSRRIVLIK 

        70         80         90        100        110        120 
PLTYMNLSGN IFPFVFSKFY MKINNLLVVV DNVDLPLGKC RLRKVGGAST HNGLRSISES 

       130        140        150        160        170        180 
LGSTKYGRLY IGVGNNSAFA LKDFVLSKFN DSELVRVKNV FNFLSEEILG IDEFSFEHKI 


ATINSSSF 

« Hide

References

[1]"The genome of Borrelia recurrentis, the agent of deadly louse-borne relapsing fever, is a degraded subset of tick-borne Borrelia duttonii."
Lescot M., Audic S., Robert C., Nguyen T.T., Blanc G., Cutler S.J., Wincker P., Couloux A., Claverie J.-M., Raoult D., Drancourt M.
PLoS Genet. 4:E1000185-E1000185(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Ly.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000976 Genomic DNA. Translation: ACH93715.1.
RefSeqYP_002222421.1. NC_011229.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING412419.BDU_793.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACH93715; ACH93715; BDU_793.
GeneID6918019.
KEGGbdu:BDU_793.
PATRIC20563708. VBIBorDut9941_0798.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0193.
HOGENOMHOG000004797.
KOK01056.
OMAWSKEENE.
OrthoDBEOG6C5RTR.

Enzyme and pathway databases

BioCycBDUT412419:GJ78-793-MONOMER.

Family and domain databases

Gene3D3.40.50.1470. 1 hit.
HAMAPMF_00083. Pept_tRNA_hydro_bact.
InterProIPR001328. Pept_tRNA_hydro.
IPR018171. Pept_tRNA_hydro_CS.
[Graphical view]
PANTHERPTHR17224. PTHR17224. 1 hit.
PfamPF01195. Pept_tRNA_hydro. 1 hit.
[Graphical view]
SUPFAMSSF53178. SSF53178. 1 hit.
TIGRFAMsTIGR00447. pth. 1 hit.
PROSITEPS01195. PEPT_TRNA_HYDROL_1. 1 hit.
PS01196. PEPT_TRNA_HYDROL_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePTH_BORDL
AccessionPrimary (citable) accession number: B5RMX9
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: November 4, 2008
Last modified: May 14, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families