Reviewed, UniProtKB/Swiss-Prot B5RMH1 (ACKA_BORDL)

Names and origin

Protein names

Recommended name:
    Acetate kinase
    EC=2.7.2.1
Alternative name(s):
    Acetokinase

Gene names

Name:	ackA
Ordered Locus Names:	BDU_626

Organism

Borrelia duttonii (strain Ly) [Complete proteome] [HAMAP]

Taxonomic identifier

412419 [NCBI]

Taxonomic lineage

Bacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Borrelia

Protein attributes

Sequence length	408 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the acetokinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro phosphorylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 408	408	Acetate kinase HAMAP MF_00020		PRO_1000089960

Sequences

	Sequence		Length	Mass (Da)
	B5RMH1-1 [UniParc]. Last modified November 4, 2008. Version 1. Checksum: 1FFF1A22C95C99E8	FASTA	408	46,430
	10 20 30 40 50 60 MKNIIILIIN TGSSSLKFTL YEYQYQSEQI LASGIIEKIK TTQAIIKIKF KNKFLELTNL 70 80 90 100 110 120 NIKSHKKALK HLIKTLTNKK TKIINYLDQI QGIGHRIVHG GAKFKNSVII NQNVLNELKK 130 140 150 160 170 180 ISHLAPLHNP IAIKVIEEMF ILFPNAKQVA CFDTSWHQTM NQKAFLYATP YSWYKDYHIR 190 200 210 220 230 240 KYGFHGLSYA YITKRTAIIL NKNIEDLNLI ILHLGNGASI NAVQKGRSYD TSMGLTPLEG 250 260 270 280 290 300 LVMGTRSGDI DPTIIPLMSK ILKKTTKQIE NILNKESGML GISCKSNDLR DIWIESNNNE 310 320 330 340 350 360 YNSKLAVEIM TYRIKKYIGS YLAALDFNID AIIFTAGIGT SDYEIRKLSL QGFEKIGIKI 370 380 390 400 DFQKNNLAID KNTEYDISSN QSNIKILVIP TNEELTILED TYDLIKDN

References

[1]

"The genome of Borrelia recurrentis, the agent of deadly louse-borne relapsing fever, is a degraded subset of tick-borne Borrelia duttonii." Lescot M., Audic S., Robert C., Nguyen T.T., Blanc G., Cutler S.J., Wincker P., Couloux A., Claverie J.-M., Raoult D., Drancourt M. PLoS Genet. 4:E1000185-E1000185(2008) [PubMed: 18787695] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000976 Genomic DNA. Translation: ACH93557.1.
RefSeq	YP_002222263.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6917852.
GenomeReviews	Gene locus BDU_626 in contig CP000976_GR.
KEGG	bdu:BDU_626.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	CFDTSWH.
Family and domain databases
HAMAP	MF_00020. [Tree]
InterPro	IPR000890. Acetate/butyrate_kinase. IPR004372. AckA. [Graphical view]
PANTHER	PTHR21060. Acetate_kin. 1 hit. PTHR21060:SF11. AckA. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. ackA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACKA_BORDL

Accession

Primary (citable) accession number: B5RMH1

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	November 4, 2008
Last modified:	November 3, 2009
This is version 11 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)