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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Borrelia duttonii (strain Ly)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:BDU_595
OrganismiBorrelia duttonii (strain Ly)
Taxonomic identifieri412419 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesBorreliaceaeBorrelia
Proteomesi
  • UP000000611 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000953351 – 585Arginine--tRNA ligaseAdd BLAST585

Proteomic databases

PRIDEiB5RME6

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi412419.BDU_595

Structurei

3D structure databases

ProteinModelPortaliB5RME6
SMRiB5RME6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi127 – 137"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107RUW Bacteria
COG0018 LUCA
HOGENOMiHOG000247211
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

B5RME6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIKTIKADLK NKIQKTIKEL ALSSNIKLDK INIVMQKPPK SEMGDLSILI
60 70 80 90 100
FEFSKILKLS IPVITQEIIK QIGNEYKTKS MGPYLNIKFN RKEYIQNTIK
110 120 130 140 150
KVNKEKENYG ANNSLQNKKT IIEFSSPNTN KPLHVGHLRN DIIGESLSRI
160 170 180 190 200
LKASGSKVTK INLINDRGTH ICKSMLAYKK FGNNITPEIA QKKGDHLIGD
210 220 230 240 250
FYVKYNEYAS QNSEIAENEI QQLLCQWEQG DEKTVQLWTK LNKWAIDGIK
260 270 280 290 300
ETYNTTNITF DKIYLESEIF KIGREVVING LKEGLCYKRE DGAICINIPT
310 320 330 340 350
EKNNIDNQNF KQKVLLRANG TSIYLTQDLG NIVARKNEFD FDEMIYVVGS
360 370 380 390 400
EQIHHFKTLF YVADKLGVTN ENNLIHLSYG MVNLPEGKMK SREGNIIDAD
410 420 430 440 450
NLIHDLSQST MLELKKRYEN EQNLQKLALN ISLGAIHYYL LKTAIHKDIL
460 470 480 490 500
FNKTESLSFT GNSGPYIQYV GARINSILDK YNNLNLANKN TNFDLLVNEN
510 520 530 540 550
EWEIIKIISE FEEYIIKASK DRNPSIIANY SYLLAKNFST YYQDTKIIDK
560 570 580
DNLELTHARI DLAKAVLQTI KNCMHLLNIP YIQKM
Length:585
Mass (Da):67,249
Last modified:November 4, 2008 - v1
Checksum:iCE96893EF201D2AE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000976 Genomic DNA Translation: ACH93532.1
RefSeqiWP_012538341.1, NC_011229.1

Genome annotation databases

EnsemblBacteriaiACH93532; ACH93532; BDU_595
KEGGibdu:BDU_595

Similar proteinsi

Entry informationi

Entry nameiSYR_BORDL
AccessioniPrimary (citable) accession number: B5RME6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: November 4, 2008
Last modified: May 23, 2018
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families
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