B5RAH6 (B5RAH6_SALG2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative dethiobiotin synthetase EMBL CAR37491.1
EC=6.3.3.3 EMBL CAR37491.1

Gene names

Name:	ynfK EMBL CAR37491.1
Ordered Locus Names:	SG1631

Organism

Salmonella gallinarum (strain 287/91 / NCTC 13346) [Complete proteome] [HAMAP]

Taxonomic identifier

550538 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella › Salmonella gallinarum

Protein attributes

Sequence length	231 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring By similarity. SAAS SAAS004472
Catalytic activity	ATP + 7,8-diaminononanoate + CO2 = ADP + phosphate + dethiobiotin. SAAS SAAS004472
Cofactor	Magnesium By similarity. SAAS SAAS004472
Pathway	Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 1/2. SAAS SAAS004472
Subcellular location	Cytoplasm By similarity SAAS SAAS004472.

Ontologies

Keywords
Biological process	Biotin biosynthesis SAAS SAAS004472
Cellular component	Cytoplasm SAAS SAAS004472
Ligand	ATP-binding SAAS SAAS004472 Magnesium SAAS SAAS004472 Metal-binding SAAS SAAS004472 Nucleotide-binding
Molecular function	Ligase SAAS SAAS004472 EMBL CAR37491.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	biotin biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW dethiobiotin synthase activity Inferred from electronic annotation. Source: EC magnesium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B5RAH6 [UniParc]. Last modified November 4, 2008. Version 1. Checksum: 844476AD7048624E	FASTA	231	24,782
	10 20 30 40 50 60 MLKRFFITGT DTSVGKTVVS RALLQALASS GKSVAGYKPV AKGSKETAEG MRNKDALVLQ 70 80 90 100 110 120 SVSSLELPYE AINPIALSEE ESSVAHSCPI NYTLLSNGLA SLSDKVDHVV VEGTGGWRSL 130 140 150 160 170 180 MNDLRPLSEW VVQEQLPVLM VVGIQEGCIN HALLTAQAVA NDGLPLIGWV ANRINPGLAH 190 200 210 220 230 YAEIIDVLGK KLPAPLIGEL PYLPRAEQRE LGQYIRLSML GSVLAVDRIM A

References

[1]

"Comparative genome analysis of Salmonella enteritidis PT4 and Salmonella gallinarum 287/91 provides insights into evolutionary and host adaptation pathways." Thomson N.R., Clayton D.J., Windhorst D., Vernikos G., Davidson S., Churcher C., Quail M.A., Stevens M., Jones M.A., Watson M., Barron A., Layton A., Pickard D., Kingsley R.A., Bignell A., Clark L., Harris B., Ormond D. , Abdellah Z., Brooks K., Cherevach I., Chillingworth T., Woodward J., Norberczak H., Lord A., Arrowsmith C., Jagels K., Moule S., Mungall K., Saunders M., Whitehead S., Chabalgoity J.A., Maskell D., Humphreys T., Roberts M., Barrow P.A., Dougan G., Parkhill J. Genome Res. 18:1624-1637(2008) [PubMed: 18583645] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM933173 Genomic DNA. Translation: CAR37491.1.
RefSeq	YP_002226606.1. NC_011274.1.
3D structure databases
ProteinModelPortal	B5RAH6.
ModBase	Search...
Protein-protein interaction databases
STRING	B5RAH6.
Proteomic databases
PRIDE	B5RAH6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6922410.
GenomeReviews	Gene locus SG1631 in contig AM933173_GR.
KEGG	seg:SG1631.
PATRIC	18501602. VBISalEnt1629_1733.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG650065.
OMA	INPGLSH.
ProtClustDB	PRK12374.
Family and domain databases
HAMAP	MF_00336. BioD. [Tree]
InterPro	IPR002586. CbiA_P_synth. IPR004472. DTB_synth_BioD. [Graphical view]
KO	K01935.
Pfam	PF01656. CbiA. 1 hit. [Graphical view]
PIRSF	PIRSF006755. DTB_synth. 1 hit.
TIGRFAMs	TIGR00347. BioD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B5RAH6_SALG2

Accession

Primary (citable) accession number: B5RAH6

Entry history

Integrated into UniProtKB/TrEMBL:	November 4, 2008
Last sequence update:	November 4, 2008
Last modified:	December 14, 2011
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)